Strain SummarySTOCK Tg(SFTPC-rtTA)5Jaw Tg(tetO/CMV-KRAS*G12C)9.1Msmi
Strain Name |
STOCK Tg(SFTPC-rtTA)5Jaw Tg(tetO/CMV-KRAS*G12C)9.1Msmi |
Strain Type(s) |
transgenic |
Strain Synonym(s) |
SP-C/Ki-ras |
Description |
Transgenic mice on a mixed background of mainly FVB/N with contributions from unspecified 129 substrain and C57BL/6. Mice contained the Tg(SFTPC-rtTA)5Jaw and Tg(tetO/CMV-KRAS*G12C)9.1Msmi transgenes. |
Strain Genetics |
Tg(tetO/CMV-KRAS*G12C)9.1Msmi |
Tg(SFTPC-rtTA)5Jaw |
Frequency | ||||||||
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Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Lung - Alveolus hyperplasia | Lung - Alveolus | doxycycline |
observed |
References: Floyd HS, Carcinogenesis 2005 Dec;26(12):2196-206 |
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Lung hyperplasia - focal | Lung | doxycycline |
observed |
References: Floyd HS, Carcinogenesis 2005 Dec;26(12):2196-206 |
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Lung tumor | Lung | doxycycline |
0 - 100 |
References: Floyd HS, Carcinogenesis 2005 Dec;26(12):2196-206 |