Strain SummarySTOCK Atmtm1Awb Rag2tm1Fwa Tg(TcraH-Y,TcrbH-Y)71Vbo
Strain Name |
STOCK Atmtm1Awb Rag2tm1Fwa Tg(TcraH-Y,TcrbH-Y)71Vbo |
Strain Type(s) |
targeted mutation (knockout) • transgenic |
Strain Synonym(s) |
HyTcrTg+Rag-/- Atm-/- |
Description |
Homozygous mutants for Atmtm1Awb and Rag2tm1Fwa also carrying the Tg(TcraH-Y,TcrbH-Y)71Vbo transgene. Bachground included contributions from at least 129S6/SvEvTac, 129S/SvEv-Gpi1c, C57BL/6, and DBA/2J. |
Strain Genetics |
Rag2tm1Fwa / Rag2tm1Fwa |
Atmtm1Awb / Atmtm1Awb | |
Tg(TcraH-Y,TcrbH-Y)71Vbo |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Leukocyte lymphoma | Thymus |
observed |
References: Petiniot LK, Proc Natl Acad Sci U S A 2000 Jun 6;97(12):6664-9 1 cytogenetic image(s) |