Strain Summary129S-Atmtm1Awb Rag2?/Rag2+
Strain Name |
129S-Atmtm1Awb Rag2?/Rag2+ |
Strain Type(s) |
not specified • targeted mutation (knockout) |
Strain Synonym(s) |
Rag2+ Atm-/- |
Description |
Mice that were either homozygous wild-type or heterozygous for the Rag2tm1Fwa mutation and were homozygous for Atmtm1Awb. Background included contributions from at least 129S6/SvEvTac and 129S/SvEv-Gpi1c. |
Strain Genetics |
Atmtm1Awb / Atmtm1Awb |
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Frequency | ||||||||
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Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Leukocyte lymphoma | Thymus |
58.33 |
References: Petiniot LK, Proc Natl Acad Sci U S A 2000 Jun 6;97(12):6664-9 |
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Mesodermal cell/mesoblast sarcoma | Mesodermal cell/mesoblast |
observed |
References: Petiniot LK, Proc Natl Acad Sci U S A 2000 Jun 6;97(12):6664-9 |
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Ovary - Granulosa cell tumor | Ovary - Granulosa cell |
observed |
References: Petiniot LK, Proc Natl Acad Sci U S A 2000 Jun 6;97(12):6664-9 |
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(Unspecified organ) tumor | (Unspecified organ) |
16.67 |
References: Petiniot LK, Proc Natl Acad Sci U S A 2000 Jun 6;97(12):6664-9 |