Strain SummaryFVB-Tg(MMTV-Erbb2)NK1Mul
Strain Name |
FVB-Tg(MMTV-Erbb2)NK1Mul |
Strain Type(s) |
transgenic |
Strain Synonym(s) |
FVB_MMTV_Neu • FVB_MMTV-Neu • MMTV-c-neu • MMTV-c-Neu |
Description |
Mice contained the transgene on an FVB background. |
Strain Genetics |
Tg(MMTV-Erbb2)NK1Mul |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Mammary gland carcinoma | Mammary gland |
observed |
References: Strumane K, J Cancer Res Clin Oncol 2009 Jan;135(1):69-80 |
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| Mammary gland tumor | Mammary gland |
observed - 100 |
References: Strumane K, J Cancer Res Clin Oncol 2009 Jan;135(1):69-80 Sites of Metastasis: Heart , Lung |
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| Mammary gland tumor - luminal | Mammary gland |
observed |
References: Roberts PJ, Clin Cancer Res 2012 Oct 1;18(19):5290-303 |
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| Mammary gland tumor - luminal | Mammary gland | carboplatin ⋅ Taxol (paclitaxel) |
observed |
References: Roberts PJ, Clin Cancer Res 2012 Oct 1;18(19):5290-303 |
||||
| Mammary gland tumor - luminal | Mammary gland | lapatinib |
observed |
References: Roberts PJ, Clin Cancer Res 2012 Oct 1;18(19):5290-303 |
||||
| Mammary gland tumor - luminal | Mammary gland | selumetinib (AZD6244) |
observed |
References: Roberts PJ, Clin Cancer Res 2012 Oct 1;18(19):5290-303 |
||||
| Mammary gland tumor - luminal | Mammary gland | BEZ235 (NVP-BEZ235-AN) |
observed |
References: Roberts PJ, Clin Cancer Res 2012 Oct 1;18(19):5290-303 |
||||
| Mammary gland tumor - luminal | Mammary gland | selumetinib (AZD6244) ⋅ BEZ235 (NVP-BEZ235-AN) |
observed |
References: Roberts PJ, Clin Cancer Res 2012 Oct 1;18(19):5290-303 |
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