Strain Summary[not specified]-Tg(CAG-Bgeo/GFP)21Lbe Tg(Pdx1-cre)6Tuv Trp53tm2Tyj/+

Strain Name

[not specified]-Tg(CAG-Bgeo/GFP)21Lbe Tg(Pdx1-cre)6Tuv Trp53tm2Tyj/+

Strain Type(s)

targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

[not specified]-Tg(CAG-Bgeo/GFP)21Lbe Tg(Ipf1-cre)1Tuv Trp53tm2Tyj/+  •  [not specified]-Tg(CAG-Bgeo/GFP)21Lbe Tg(Ipf1-cre)6Tuv Trp53tm2Tyj/+  •  [not specified]-Tg(CAG-Bgeo/GFP)21Lbe Tg(Pdx1-cre)6Tuv Trp53tm2Tyj/+  •  PC  •  Pdx1-Cre-GFP, LSL-Trp53R172H/+

Description

The genetic background was not specified but contained contributions from at least FVB/N and 129S4/SvJae. Mice were heterozygous for Trp53tm2Tyj and carried the Tg(Pdx1-cre)6Tuv and Tg(CAG-Bgeo/GFP)21Lbe transgenes.

Strain Genetics

Tg(CAG-Bgeo/GFP)21Lbe
Tg(Pdx1-cre)6Tuv
Trp53tm2Tyj / Trp53+

Models

2 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Pancreas - Duct pancreatic intraepithelial neoplasia (PanIN) Pancreas - Duct

0

References: Morton JP, Proc Natl Acad Sci U S A 2010 Jan 5;107(1):246-51

Pancreas adenocarcinoma - ductal Pancreas

0

References: Morton JP, Proc Natl Acad Sci U S A 2010 Jan 5;107(1):246-51