Strain SummarySTOCK Cdkn2atm1Rdp/+ Krastm4Tyj/+ Tg(CAG-Bgeo/GFP)21Lbe Tg(Pdx1-cre)6Tuv
Strain Name |
STOCK Cdkn2atm1Rdp/+ Krastm4Tyj/+ Tg(CAG-Bgeo/GFP)21Lbe Tg(Pdx1-cre)6Tuv |
Strain Type(s) |
targeted mutation (conditional) • transgenic |
Strain Synonym(s) |
KIC • STOCK Cdkn2atm1Rdp/+ Krastm4Tyj/+ Tg(CAG-Bgeo/GFP)21Lbe Tg(Ipf1-cre)1Tuv • STOCK Cdkn2atm1Rdp/+ Krastm4Tyj/+ Tg(CAG-Bgeo/GFP)21Lbe Tg(Ipf1-cre)6Tuv • STOCK Cdkn2atm1Rdp/+ Krastm4Tyj/+ Tg(CAG-Bgeo/GFP)21Lbe Tg(Pdx1-cre)6Tuv |
Description |
Background had contributions from FVB/N, C57BL/6J, SJL, and multiple 129 substrains. Mice were heterozygous Krastm4Tyj and Cdkn2atm1Rdp and carried the Tg(Pdx1-cre)6Tuv and Tg(CAG-Bgeo/GFP)21Lbe transgenes. |
Strain Genetics |
Cdkn2atm1Rdp / Cdkn2a+ |
Tg(CAG-Bgeo/GFP)21Lbe | |
Tg(Pdx1-cre)6Tuv | |
Krastm4Tyj / Kras+ |
Frequency | ||||||||
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Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Pancreas - Duct pancreatic intraepithelial neoplasia (PanIN) | Pancreas - Duct |
observed |
References: Morton JP, Proc Natl Acad Sci U S A 2010 Jan 5;107(1):246-51 2 pathology image(s) |
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Pancreas adenocarcinoma - ductal | Pancreas |
observed |
References: Morton JP, Proc Natl Acad Sci U S A 2010 Jan 5;107(1):246-51 3 pathology image(s) |