Strain SummarySTOCK Brca1tm2Cxd Tg(MMTV-cre)4Mam Trp53tm1Brd

Strain Name

STOCK Brca1tm2Cxd Tg(MMTV-cre)4Mam Trp53tm1Brd

Strain Type(s)

targeted mutation (conditional)  •  targeted mutation (knockout)  •  transgenic

Strain Synonym(s)

Brca1 Co/Co;MMTV-cre;p53  •  loss of BRCA1 and p53

Description

Compound mutant mice. The genetic background of these mice was a mixture of at least C57BL/6, FVB, 129S6/SvEvTac, and 129S7/SvEvBrd-Hprt+.

Strain Genetics

Tg(MMTV-cre)4Mam
Brca1tm2Cxd / Brca1tm2Cxd
Trp53tm1Brd / Trp53tm1Brd

Models

1 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Mammary gland tumor Mammary gland

observed

References: Deeb KK, Cancer Res 2007 Sep 1;67(17):8065-8080