Strain SummaryHcB-19/Dem-Txnip^Hyplip1

Strain Name	HcB-19/Dem-Txnip^Hyplip1
Strain Type(s)	recombinant congenic • spontaneous mutation
Strain Synonym(s)	HcB-19/Dem • Txnip-deficient
Description	Recombinant congenic strain with C3H/DiSnA (background strain) and C57BL/10ScSnA (donor strain). Mice were homozygous for the Txnip^Hyplip1 mutation. Background was 87.7% C3H/DiSnA and 12.3% C57BL/10ScSnA.
Strain Genetics	List all models in MMHCdb carrying the Txnip^Hyplip1 allele Txnip^Hyplip1 / Txnip^Hyplip1

Models
3 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Liver hepatocellular carcinoma	Liver					observed	References: Sheth SS, Oncogene 2006 Jun 15;25(25):3528-36
Liver normal tissue (control)	Liver					not applicable	References: Sheth SS, Oncogene 2006 Jun 15;25(25):3528-36
Liver tumor	Liver		25	51.79		observed - 66.09	References: Sheth SS, Oncogene 2006 Jun 15;25(25):3528-36

Models