Strain SummaryBALB/cJ-Trp53tm1Tyj/+
Strain Name |
BALB/cJ-Trp53tm1Tyj/+ |
Strain Type(s) |
targeted mutation (knockout) |
Strain Synonym(s) |
Balbc_p53het • BALB_p53het • p53+/- • Trp53+/? • p53+/- • p53+/- • Trp53tm1Tyj |
Description |
Heterozygous mice. The genetic background of these mice was predominantly BALB/cJ. It also contained some 129S2/SvPas and possibly some other strain(s). |
Strain Genetics |
Trp53tm1Tyj / Trp53+ |
Frequency | ||||||||
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Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Mammary gland carcinoma | Mammary gland | gamma-radiation |
observed |
observed |
References: Herschkowitz JI, Genome Biol 2007;8(5):R76 ⋅ Pfefferle AD, Genome Biol 2013;14(11):R125 |
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Mammary gland tumor | Mammary gland | ionizing radiation |
observed |
References: Herschkowitz JI, Proc Natl Acad Sci U S A 2012 Feb 21;109(8):2778-83 |