Strain SummaryC57BL/6-Brca1^tm2Cxd Trp53^tm1Brd/+ Tg(MMTV-cre)4Mam

Strain Name	C57BL/6-Brca1^tm2Cxd Trp53^tm1Brd/+ Tg(MMTV-cre)4Mam
Strain Type(s)	targeted mutation (conditional) • targeted mutation (knockout) • transgenic
Strain Synonym(s)	Brca1tm1Cxd/Brca1tm2Cxd;Trp53tm1Brd/Trp53+;Tg(MMTV-cre)4Mam/0 • C57Bl6_MMTV_Cre_Brca1CoCo_p53het • C57Bl6_MMTV_Cre_BRCA1CoCo_p53het • Brca1^Co/Co;TgMMTV-Cre;p53^+/- • TgMMTV-Cre Brca1^Co/Co, Trp53^+/?
Description	Compound mutant mice. The genetic background of these mice was predominantly C57BL/6. It also contained some 129S6/SvEvTac, some 129S7/SvEvBrd-Hprt⁺, some FVB, and possibly some other strain(s).
Strain Genetics	List all models in MMHCdb carrying the Trp53^tm1Brd allele Trp53^tm1Brd / Trp53⁺
	List all models in MMHCdb carrying the Tg(MMTV-cre)4Mam allele Tg(MMTV-cre)4Mam
	List all models in MMHCdb carrying the Brca1^tm2Cxd allele Brca1^tm2Cxd / Brca1^tm2Cxd

Models
1 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Mammary gland carcinoma	Mammary gland		observed				References: Herschkowitz JI, Genome Biol 2007;8(5):R76

Models