Strain SummaryB6.Cg-Ptentm1Hwu Tg(Osr1-cre)4Mrt

Strain Name

 B6.Cg-Ptentm1Hwu Tg(Osr1-cre)4Mrt

Strain Type(s)

 targeted mutation (conditional)  •  transgenic

Strain Synonym(s)

 ptenloxP/loxPOsr-1Cre  •  PtenloxP/loxP;Osr-1Cre  •  PtenloxP/loxP:Osr1-Cre  •  PtenloxP/loxPOsr-1Cre+

Description

 Compound mutant mice. These mice had been backcrossed more than 5 times to C57BL/6J and then intercrossed. The genetic background also may include some 129S4/SvJae, FVB/N, and BALB/c.

Strain Genetics

 Ptentm1Hwu / Ptentm1Hwu
Tg(Osr1-cre)4Mrt

Models

16 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Lung carcinoma Lung

3.7

References: Kwak MK, PLoS One 2013;8(1):e53476

Mammary gland adenocarcinoma Mammary gland

9.4

References: Kwak MK, PLoS One 2013;8(1):e53476

Mesodermal cell/mesoblast sarcoma Gastrointestinal tract

6.25

References: Kwak MK, PLoS One 2013;8(1):e53476

PNS - Nerve sheath tumor - malignant PNS - Nerve sheath

3.7

References: Kwak MK, PLoS One 2013;8(1):e53476

Prostate gland - Anterior lobe prostatic intraepithelial neoplasia - high grade (HGPIN) Prostate gland - Anterior lobe

100

References: Kwak MK, PLoS One 2013;8(1):e53476

9 pathology image(s)
Prostate gland - Dorsolateral lobe prostatic intraepithelial neoplasia - high grade (HGPIN) Prostate gland - Dorsolateral lobe

100

References: Kwak MK, PLoS One 2013;8(1):e53476

9 pathology image(s)
Prostate gland - Ventral lobe prostatic intraepithelial neoplasia - high grade (HGPIN) Prostate gland - Ventral lobe

100

References: Kwak MK, PLoS One 2013;8(1):e53476

9 pathology image(s)
Prostate gland adenocarcinoma - well-differentiated Prostate gland

12.5

References: Kwak MK, PLoS One 2013;8(1):e53476

3 pathology image(s)
Prostate gland carcinoma Prostate gland

62.5

References: Kwak MK, PLoS One 2013;8(1):e53476

6 pathology image(s)
Prostate gland carcinoma - solid Prostate gland

50

References: Kwak MK, PLoS One 2013;8(1):e53476

9 pathology image(s)
Prostate gland lesion Prostate gland

0

References: Kwak MK, PLoS One 2013;8(1):e53476

Prostate gland prostatic intraepithelial neoplasia - high grade (HGPIN) Prostate gland

100

References: Kwak MK, PLoS One 2013;8(1):e53476

26 pathology image(s)
Prostate gland prostatic intraepithelial neoplasia - high grade (HGPIN) Prostate gland castration

100

References: Kwak MK, PLoS One 2013;8(1):e53476

Prostate gland tumor Prostate gland

0

References: Kwak MK, PLoS One 2013;8(1):e53476

Prostate gland tumor Prostate gland castration

observed

References: Kwak MK, PLoS One 2013;8(1):e53476

6 pathology image(s)
(Unspecified organ) cystadenoma - papillary (Unspecified organ)

3.7

References: Kwak MK, PLoS One 2013;8(1):e53476