Strain SummaryC57BL/6J-Krt14tm1.1(cre)Wbm/+ Rad51ctm1Sks/+ Trp53tm1Brn

Strain Name

C57BL/6J-Krt14tm1.1(cre)Wbm/+ Rad51ctm1Sks/+ Trp53tm1Brn

Strain Type(s)

targeted mutation (conditional)  •  targeted mutation (knock-in)

Strain Synonym(s)

p53/K14cre  •  p53/K14cre  •  p53lox/lox; K14cre/+  •  p53lox/lox; Rad51cneo/+; K14cre/+  •  Trp53tm1Brn; Krt14tm1.1(cre)Wbm/+

Description

Compound mutant mice. The genetic background of these mice was stated to be predominantly C57BL/6J but no backcrossing details were given. It also includes some 129P2/OlaHsd, 129S1/Sv, and possibly some NMRI.

Strain Genetics

Krt14tm1.1(cre)Wbm / Krt14+
Trp53tm1Brn / Trp53tm1Brn
Rad51ctm1Sks / Rad51c+

Models

13 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Ear - Zymbal gland carcinoma in situ Ear - Zymbal gland

0

References: Tumiati M, J Pathol 2015 Jan;235(1):136-46

Ear - Zymbal gland squamous cell carcinoma Ear - Zymbal gland

0

References: Tumiati M, J Pathol 2015 Jan;235(1):136-46

Eye - Meibomian gland squamous cell carcinoma Eye - Meibomian gland

0

References: Tumiati M, J Pathol 2015 Jan;235(1):136-46

Mammary gland carcinoma Mammary gland

0

References: Tumiati M, J Pathol 2015 Jan;235(1):136-46

Mammary gland tumor Mammary gland

observed

References: Tumiati M, Oncogene 2016 Jan 25;():

Muzzle carcinoma - sebaceous Muzzle

0

References: Tumiati M, J Pathol 2015 Jan;235(1):136-46

Preputial gland (male) carcinoma in situ Preputial gland (male)

0 - 5.3

References: Tumiati M, J Pathol 2015 Jan;235(1):136-46

Preputial gland (male) hyperplasia Preputial gland (male)

15.8 - 40

References: Tumiati M, J Pathol 2015 Jan;235(1):136-46

Preputial gland (male) squamous cell carcinoma Preputial gland (male)

10.5

References: Tumiati M, J Pathol 2015 Jan;235(1):136-46

Skin lesion - benign Skin

5.3

References: Tumiati M, J Pathol 2015 Jan;235(1):136-46

Skin papilloma Skin

5.3

References: Tumiati M, J Pathol 2015 Jan;235(1):136-46

Skin squamous cell carcinoma Skin

5.3

References: Tumiati M, J Pathol 2015 Jan;235(1):136-46

(Unspecified organ) tumor (Unspecified organ)

15.8 - 29

References: Tumiati M, J Pathol 2015 Jan;235(1):136-46