Strain SummaryC57BL/6J-Krt14^{tm1.1(cre)Wbm}/+ Rad51c^tm1Sks Trp53^tm1Brn

Strain Name	C57BL/6J-Krt14^{tm1.1(cre)Wbm}/+ Rad51c^tm1Sks Trp53^tm1Brn
Strain Type(s)	targeted mutation (conditional) • targeted mutation (knock-in)
Strain Synonym(s)	Rad51c/p53/K14cre • Rad51c/p53/K14cre • Rad51c^neo/neo; p53^lox/lox; K14^cre/+ • Rad51c^n/n; p53 lox/lox; K14^cre/+ • Rad51c^tm1Sks; Trp53^tm1Brn; Krt14^{tm1.1(cre)Wbm/+}
Description	Compound mutant mice. The genetic background of these mice was stated to be predominantly C57BL/6J but no backcrossing details were given. It also includes some 129P2/OlaHsd, 129S1/Sv, and possibly some NMRI.
Strain Genetics	List all models in MMHCdb carrying the Krt14^{tm1.1(cre)Wbm} allele Krt14^{tm1.1(cre)Wbm} / Krt14⁺
	List all models in MMHCdb carrying the Rad51c^tm1Sks allele Rad51c^tm1Sks / Rad51c^tm1Sks
	List all models in MMHCdb carrying the Trp53^tm1Brn allele Trp53^tm1Brn / Trp53^tm1Brn

Models
24 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Ear - Zymbal gland carcinoma in situ	Ear - Zymbal gland			2.9			References: Tumiati M, J Pathol 2015 Jan;235(1):136-46
Ear - Zymbal gland squamous cell carcinoma	Ear - Zymbal gland			20.6			References: Tumiati M, J Pathol 2015 Jan;235(1):136-46
Eye - Meibomian gland carcinoma in situ	Eye - Meibomian gland			observed			References: Tumiati M, J Pathol 2015 Jan;235(1):136-46
Eye - Meibomian gland squamous cell carcinoma	Eye - Meibomian gland			14.7			References: Tumiati M, J Pathol 2015 Jan;235(1):136-46
Mammary gland adenomyoepithelioma	Mammary gland		observed				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland carcinoma	Mammary gland			2.9			References: Tumiati M, J Pathol 2015 Jan;235(1):136-46
Mammary gland carcinoma - adenosquamous	Mammary gland		observed				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland carcinoma - solid	Mammary gland		observed				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland carcinosarcoma	Mammary gland		observed				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland neoplasia - epithelial	Mammary gland		observed				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland tumor	Mammary gland		100				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland tumor - sarcomatous	Mammary gland		observed				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland tumor - squamous	Mammary gland		observed				References: Tumiati M, Oncogene 2016 Jan 25;():
Muzzle carcinoma - sebaceous	Muzzle			8.8			References: Tumiati M, J Pathol 2015 Jan;235(1):136-46
Oral cavity squamous cell carcinoma	Oral cavity			observed			References: Tumiati M, J Pathol 2015 Jan;235(1):136-46
Preputial gland (male) carcinoma in situ	Preputial gland (male)			0 - 76.5			References: Tumiati M, J Pathol 2015 Jan;235(1):136-46
Preputial gland (male) dysplasia	Preputial gland (male)			observed			References: Tumiati M, J Pathol 2015 Jan;235(1):136-46
Preputial gland (male) hyperplasia	Preputial gland (male)			0 - 100			References: Tumiati M, J Pathol 2015 Jan;235(1):136-46
Preputial gland (male) metaplasia	Preputial gland (male)			observed			References: Tumiati M, J Pathol 2015 Jan;235(1):136-46
Preputial gland (male) squamous cell carcinoma	Preputial gland (male)			17.6			References: Tumiati M, J Pathol 2015 Jan;235(1):136-46
Skin lesion - benign	Skin			29.4			References: Tumiati M, J Pathol 2015 Jan;235(1):136-46
Skin papilloma	Skin			8.8			References: Tumiati M, J Pathol 2015 Jan;235(1):136-46
Skin squamous cell carcinoma	Skin			70.6			References: Tumiati M, J Pathol 2015 Jan;235(1):136-46
(Unspecified organ) tumor	(Unspecified organ)			100			References: Tumiati M, J Pathol 2015 Jan;235(1):136-46

Strain Name

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Description

Strain Genetics

Models