Strain SummaryC57BL/6-ApcMin/+ Il33tm1.1(KOMP)Vlcg
Strain Name |
C57BL/6-ApcMin/+ Il33tm1.1(KOMP)Vlcg |
Strain Type(s) |
chemically induced mutation • targeted mutation (knockout) |
Strain Synonym(s) |
ApcMin/+,Il33-/- |
Description |
Compound mutant mice on a C57BL/6 background at least 75% C57BL/6J the rest being C57BL/6NCrl with possible contribution from BALB/cJ and/or C57BL/6NTac. Mice may also carry the Tg(CMV-cre)1Cgn transgene. |
Strain Genetics |
ApcMin / Apc+ |
Il33tm1.1(KOMP)Vlcg / Il33tm1.1(KOMP)Vlcg |
Frequency | ||||||||
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Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Intestine polyp | Intestine |
observed |
References: Maywald RL, Proc Natl Acad Sci U S A 2015 May 12;112(19):E2487-96 |
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Intestine tumor | Intestine |
observed |
References: Maywald RL, Proc Natl Acad Sci U S A 2015 May 12;112(19):E2487-96 |