Strain Summary(C57BL/6J x PWK/PhJ)F1-Tg(TRAMP)8247Ng

Strain Name

(C57BL/6J x PWK/PhJ)F1-Tg(TRAMP)8247Ng

Strain Type(s)

hybrid  •  transgenic

Strain Synonym(s)

C57BL/6-Tg(TRAMP)8247Ng/J x PWK/PhJ F1  •  PB-TAg  •  TRAMP F1  •  TRAMP-PWK  •  TRAMP x PWK/PhJ F1

Description

These mice were generated by crossing C57BL/6-Tg(TRAMP)8247Ng/J female mice with PWK/PhJ male mice.

Strain Genetics

Tg(TRAMP)8247Ng

Models

8 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Prostate gland - Anterior lobe hyperplasia Prostate gland - Anterior lobe

observed

References: Patel SJ, PLoS One 2013;8(4):e61848

Prostate gland - Dorsolateral lobe hyperplasia Prostate gland - Dorsolateral lobe

observed

References: Patel SJ, PLoS One 2013;8(4):e61848

Prostate gland carcinoma - neuroendocrine Prostate gland

0 - 25

References: Patel SJ, PLoS One 2013;8(4):e61848

Sites of Metastasis: Lung

Prostate gland hyperplasia Prostate gland

67 - 100

References: Patel SJ, PLoS One 2013;8(4):e61848

Prostate gland prostatic intraepithelial neoplasia (PIN) Prostate gland

67 - 100

References: Patel SJ, PLoS One 2013;8(4):e61848

Seminal vesicle hyperplasia Seminal vesicle

0 - 100

References: Patel SJ, PLoS One 2013;8(4):e61848

Seminal vesicle tumor Seminal vesicle

observed

References: Patel SJ, PLoS One 2013;8(4):e61848

Seminal vesicle tumor - phyllodes-like Seminal vesicle

50

References: Patel SJ, PLoS One 2013;8(4):e61848