Strain SummaryC57BL/6J-Krt14^{tm1.1(cre)Wbm}/+ Trp53^tm1Brn

Strain Name	C57BL/6J-Krt14^{tm1.1(cre)Wbm}/+ Trp53^tm1Brn
Strain Type(s)	targeted mutation (conditional) • targeted mutation (knock-in)
Strain Synonym(s)	p53/K14cre
Description	Homozygous Trp53^tm1Brn, heterozygous Krt14^{tm1.1(cre)Wbm} mice stated to be on a predominantly C57BL/6J background, but no backcrossing details were given. It also may include some 129P2/OlaHsd and/or 129S1/Sv.
Strain Genetics	List all models in MMHCdb carrying the Krt14^{tm1.1(cre)Wbm} allele Krt14^{tm1.1(cre)Wbm} / Krt14⁺
	List all models in MMHCdb carrying the Trp53^tm1Brn allele Trp53^tm1Brn / Trp53^tm1Brn

Models
34 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Clitoral gland squamous cell carcinoma	Clitoral gland		7.41				References: Tumiati M, Oncogene 2016 Jan 25;():
Ear - Zymbal gland squamous cell carcinoma	Ear - Zymbal gland		7.41				References: Tumiati M, Oncogene 2016 Jan 25;():
Eye - Meibomian gland squamous cell carcinoma	Eye - Meibomian gland		0				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland adenomyoepithelioma	Mammary gland		0 - observed				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland carcinoma	Mammary gland		70.37				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland carcinoma - acinar	Mammary gland		0				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland carcinoma - adenosquamous	Mammary gland		3.7				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland carcinoma - cribriform	Mammary gland		0				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland carcinoma - glandular	Mammary gland		3.7				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland carcinoma - papillary	Mammary gland		0				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland carcinoma - solid	Mammary gland		observed				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland carcinoma - solid - poorly differentiated	Mammary gland		observed				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland carcinosarcoma	Mammary gland		observed - 3.7				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland cyst - squamous	Mammary gland		0				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland lesion	Mammary gland		observed				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland mammary intraepithelial neoplasia (MIN)	Mammary gland		0 - 29.63				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland mammary intraepithelial neoplasia (MIN) - adenosquamous	Mammary gland		0				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland mammary intraepithelial neoplasia (MIN) - solid	Mammary gland		29.63				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland metaplasia - cartilaginous	Mammary gland		0				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland neoplasia - epithelial	Mammary gland		observed				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland tumor	Mammary gland		observed - 92.59				References: Tumiati M, Oncogene 2016 Jan 25;():
Mammary gland tumor - sarcomatous	Mammary gland		observed				References: Tumiati M, Oncogene 2016 Jan 25;():
Mesodermal cell/mesoblast sarcoma	Muscle		7.41				References: Tumiati M, Oncogene 2016 Jan 25;():
Muscle myosarcoma	Muscle		7.41				References: Tumiati M, Oncogene 2016 Jan 25;():
Muzzle carcinoma	Muzzle		3.7				References: Tumiati M, Oncogene 2016 Jan 25;():
Salivary gland squamous cell carcinoma	Salivary gland		3.7				References: Tumiati M, Oncogene 2016 Jan 25;():
Skin - Epidermis cyst	Skin - Epidermis		observed				References: Tumiati M, Oncogene 2016 Jan 25;():
Skin - Epidermis papilloma	Skin - Epidermis		observed				References: Tumiati M, Oncogene 2016 Jan 25;():
Skin gland - Sebaceous gland squamous cell carcinoma	Skin gland - Sebaceous gland		7.41				References: Tumiati M, Oncogene 2016 Jan 25;():
Skin gland - Sebaceous gland tumor	Skin gland - Sebaceous gland		14.81				References: Tumiati M, Oncogene 2016 Jan 25;():
Skin lesion	Skin		7.41				References: Tumiati M, Oncogene 2016 Jan 25;():
Skin squamous cell carcinoma	Skin		14.81				References: Tumiati M, Oncogene 2016 Jan 25;():
Skin tumor	Skin		18.52				References: Tumiati M, Oncogene 2016 Jan 25;():
(Unspecified organ) tumor	(Unspecified organ)		7.41 - 81.48				References: Tumiati M, Oncogene 2016 Jan 25;():

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Description

Strain Genetics

Models