Strain Summary[not specified]-Krastm4.1Bbd
Strain Name |
[not specified]-Krastm4.1Bbd |
Strain Type(s) |
targeted mutation (knock-in) |
Strain Synonym(s) |
K-RasV14I • K-RasV14I • V14I |
Description |
Homozygous mice. The genetic background of these mice was not specified but included at least 129 (129X1/SvJ and/or 129S1/Sv) and possibly some other strain(s). |
Strain Genetics |
Krastm4.1Bbd / Krastm4.1Bbd |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Pancreas adenocarcinoma - ductal | Pancreas | caerulein |
0 |
References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17 |
||||
Pancreas pancreatic intraepithelial neoplasia (PanIN) - high grade | Pancreas | caerulein |
60 - 87.5 |
References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17 |
||||
Pancreas pancreatic intraepithelial neoplasia (PanIN) - low grade | Pancreas | caerulein |
60 - 87.5 |
References: Hernandez-Porras I, J Pathol 2016 Jun;239(2):206-17 |