Strain SummaryB6.129P2-Ercc2tm2(ERCC2)Jhjh
Strain Name |
B6.129P2-Ercc2tm2(ERCC2)Jhjh |
Strain Type(s) |
congenic • targeted mutation (knock-in) |
Strain Synonym(s) |
XpdTTD |
Description |
Homozygous Ercc2 mice on a congenic C57BL/6NHsd. Allele was through 129P2/OlaHsd. |
Strain Genetics |
Ercc2tm2(ERCC2)Jhjh / Ercc2tm2(ERCC2)Jhjh |
| Frequency | ||||||||
|---|---|---|---|---|---|---|---|---|
| Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
| Adrenal gland - Medulla pheochromocytoma | Adrenal gland - Medulla |
8.57 |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
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| Blood vessel hemangioma | Blood vessel |
8.57 |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| Blood vessel hemangiosarcoma | Blood vessel |
2.86 |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| Bone osteosarcoma | Bone |
0 |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| Eye - Harderian gland adenoma | Eye - Harderian gland |
0 |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| Head squamous cell carcinoma | Head |
2.86 |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| Intestine - Small Intestine - Duodenum hyperplasia - atypical | Intestine - Small Intestine - Duodenum |
17.6 |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| Intestine - Small Intestine - Duodenum hyperplasia - atypical - epithelial | Intestine - Small Intestine - Duodenum |
observed |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| Intestine - Small Intestine - Duodenum tumor | Intestine - Small Intestine - Duodenum |
0 |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| Leukocyte - Lymphocyte lymphoma | (Unspecified organ) |
8.57 |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma | (Unspecified organ) |
8.57 |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| Liver hepatocellular carcinoma | Liver |
2.86 |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| Lung carcinoma - bronchioalveolar | Lung |
2.86 |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| Mesodermal cell/mesoblast sarcoma | Liver |
0 |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| Muscle - Smooth - Intestinal leiomyosarcoma | Intestine - Small Intestine |
0 |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| Pituitary gland - Pars distalis adenoma | Pituitary gland - Pars distalis |
8.57 |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| Pituitary gland adenoma | Pituitary gland |
8.6 |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| Skin - Melanocyte melanoma - benign | Skin - Melanocyte |
2.86 |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| Skin hyperplasia - sebaceous | Skin |
observed |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| Skin lesion | Skin |
observed |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| Thyroid gland - Follicular cell adenoma | Thyroid gland - Follicular cell |
5.71 |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| Thyroid gland - Follicular cell hyperplasia | Thyroid gland - Follicular cell |
5.9 |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| (Unspecified organ) lesion | (Unspecified organ) |
observed |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| (Unspecified organ) neoplasm | (Unspecified organ) |
20 |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| (Unspecified organ) tumor | (Unspecified organ) |
54.29 |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| (Unspecified organ) tumor - benign | (Unspecified organ) |
observed |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
|||||
| (Unspecified organ) tumor - malignant | (Unspecified organ) |
observed |
References: Wijnhoven SW, DNA Repair (Amst) 2005 Nov 21;4(11):1314-24 |
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