Strain SummaryC57BL/6-Trp53em1Yoli

Strain Name

C57BL/6-Trp53em1Yoli

Strain Type(s)

endonuclease-mediated mutation

Strain Synonym(s)

p53C/C  •  Trp531755C/1755C

Description

Homozygous mice. The genetic background of these mice was C57BL/6.

Strain Genetics

Trp53em1Yoli / Trp53em1Yoli

Models

19 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
CNS - Brain glioma CNS - Brain retrovirus expressing human PDGFB

100

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

Intestine - Small Intestine carcinoma Intestine - Small Intestine

observed

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell lymphoma - follicular Leukocyte - Lymphocyte - B-lymphocyte - Follicular center cell

31

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell plasmacytoma Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell

2.8

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell plasmacytoma - malignant Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell

2.8

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

Leukocyte - Lymphocyte - B-lymphocyte lymphoma Leukocyte - Lymphocyte - B-lymphocyte gamma-radiation

observed

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

Leukocyte - Lymphocyte - B-lymphocyte lymphoma - diffuse large cell (DLCL) Leukocyte - Lymphocyte - B-lymphocyte

17

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

Leukocyte - Lymphocyte - B-lymphocyte lymphoma - splenic marginal zone Leukocyte - Lymphocyte - B-lymphocyte

14

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

Leukocyte - Lymphocyte - B-lymphocyte tumor - malignant Leukocyte - Lymphocyte - B-lymphocyte

67

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

Leukocyte - Lymphocyte - T-lymphocyte lymphoma Leukocyte - Lymphocyte - T-lymphocyte gamma-radiation

observed

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

Leukocyte - Lymphocyte - T-lymphocyte lymphoma Thymus

0

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

Leukocyte lymphoma Leukocyte

observed

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

Leukocyte lymphoma Leukocyte gamma-radiation

observed

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

Lung adenocarcinoma Lung

observed

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast

observed

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

Mesodermal cell/mesoblast sarcoma Mesodermal cell/mesoblast gamma-radiation

0

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

Ovary tumor - malignant Ovary gamma-radiation

observed

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

(Unspecified organ) tumor (Unspecified organ)

67

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

(Unspecified organ) tumor (Unspecified organ) gamma-radiation

92

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061