Strain SummaryB6FVBF1-Tg(MMTVneu)202Mul Trp53em1Yoli/+

Strain Name

B6FVBF1-Tg(MMTVneu)202Mul Trp53em1Yoli/+

Strain Type(s)

endonuclease-mediated mutation  •  hybrid  •  transgenic

Strain Synonym(s)

p53+/C;Erbb2  •  p53+/C;Erbb2 (F1)

Description

Heterozygous Trp53 mutant mice also carrying the transgene. The genetic background of these mice was (C57BL/6 x FVB/N)F1.

Strain Genetics

Tg(MMTVneu)202Mul
Trp53em1Yoli / Trp53+

Models

6 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Leukocyte lymphoma Leukocyte

9.5

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

Mammary gland neoplasia Mammary gland lentivirus expressing miR-382

observed

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

Mammary gland tumor Mammary gland

24

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

Sites of Metastasis: Lung

4 pathology image(s)

Mammary gland tumor Mammary gland lentivirus control vector

0

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

Mammary gland tumor Mammary gland lentivirus expressing miR-382

88

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

(Unspecified organ) tumor (Unspecified organ)

33

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061