Strain SummaryB6FVBF1-Tg(MMTVneu)202Mul Trp53em1Yoli/+
Strain Name |
B6FVBF1-Tg(MMTVneu)202Mul Trp53em1Yoli/+ |
Strain Type(s) |
endonuclease-mediated mutation • hybrid • transgenic |
Strain Synonym(s) |
p53+/C;Erbb2 • p53+/C;Erbb2 (F1) |
Description |
Heterozygous Trp53 mutant mice also carrying the transgene. The genetic background of these mice was (C57BL/6 x FVB/N)F1. |
Strain Genetics |
Tg(MMTVneu)202Mul |
Trp53em1Yoli / Trp53+ |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Leukocyte lymphoma | Leukocyte |
9.5 |
References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061 |
|||||
Mammary gland neoplasia | Mammary gland | lentivirus expressing miR-382 |
observed |
References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061 |
||||
Mammary gland tumor | Mammary gland |
24 |
References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061 Sites of Metastasis: Lung 4 pathology image(s) |
|||||
Mammary gland tumor | Mammary gland | lentivirus control vector |
0 |
References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061 |
||||
Mammary gland tumor | Mammary gland | lentivirus expressing miR-382 |
88 |
References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061 |
||||
(Unspecified organ) tumor | (Unspecified organ) |
33 |
References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061 |