Strain SummaryB6FVBF1-Tg(MMTVneu)202Mul Trp53tm1Tyj/+
Strain Name |
B6FVBF1-Tg(MMTVneu)202Mul Trp53tm1Tyj/+ |
Strain Type(s) |
endonuclease-mediated mutation • hybrid • transgenic |
Strain Synonym(s) |
p53+/?;Erbb2 |
Description |
Heterozygous Trp53 mutant mice also carrying the transgene. The genetic background of these mice was (C57BL/6 x FVB/N)F1. It also contained a small amount of 129S2/SvPas from the original ES cell line used to generate the mutant Trp53 allele. |
Strain Genetics |
Trp53tm1Tyj / Trp53+ |
Tg(MMTVneu)202Mul |
Frequency | ||||||||
---|---|---|---|---|---|---|---|---|
Model Name | Organ Affected | Tumor Inducing Agent(s) | Female | Male | Mixed Pop. | Unspecified | Additional Information | Model Details |
Leukocyte lymphoma | Leukocyte |
33 |
References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061 |
|||||
Mammary gland tumor | Mammary gland |
40 |
References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061 |
|||||
(Unspecified organ) tumor | (Unspecified organ) |
60 |
References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061 |