Strain SummaryB6FVBF1-Tg(MMTVneu)202Mul Trp53tm1Tyj/+

Strain Name

B6FVBF1-Tg(MMTVneu)202Mul Trp53tm1Tyj/+

Strain Type(s)

endonuclease-mediated mutation  •  hybrid  •  transgenic

Strain Synonym(s)

p53+/?;Erbb2

Description

Heterozygous Trp53 mutant mice also carrying the transgene. The genetic background of these mice was (C57BL/6 x FVB/N)F1. It also contained a small amount of 129S2/SvPas from the original ES cell line used to generate the mutant Trp53 allele.

Strain Genetics

Trp53tm1Tyj / Trp53+
Tg(MMTVneu)202Mul

Models

3 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Leukocyte lymphoma Leukocyte

33

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

Mammary gland tumor Mammary gland

40

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061

(Unspecified organ) tumor (Unspecified organ)

60

References: Deng Q, Nat Commun 2019 Nov 7;10(1):5061