Strain SummaryB6.B6129S4F1-Palb2^tm1.1Bix

Strain Name	B6.B6129S4F1-Palb2^tm1.1Bix
Strain Type(s)	congenic • targeted mutation (knock-in)
Strain Synonym(s)	Palb2^CC6 (LKK-AAA)
Description	Homozygous mice. The genetic background of these mice was congenic for C57BL/6. The mutation was originally generated in (C57BL/6 x 129S4/SvJae)F1 ES cells.
Strain Genetics	List all models in MMHCdb carrying the Palb2^tm1.1Bix allele Palb2^tm1.1Bix / Palb2^tm1.1Bix

Models
7 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Leukocyte lymphoma	Thymus	cesium-137	75	83		100	References: Mahdi AH, Cancer Res 2018 Jul 15;78(14):3969-3981
Leukocyte lymphoma	Thymus	cesium-137 ⋅ 2-[(aminocarbonyl)amino]-5-(4-fluorophenyl)-3-thiophenecarboxamide (TPCA-1)				90	References: Mahdi AH, Cancer Res 2018 Jul 15;78(14):3969-3981
Liver tumor	Liver	cesium-137	8.3				References: Mahdi AH, Cancer Res 2018 Jul 15;78(14):3969-3981
Mammary gland tumor	Mammary gland	cesium-137	0				References: Mahdi AH, Cancer Res 2018 Jul 15;78(14):3969-3981
Mesodermal cell/mesoblast sarcoma	Mesodermal cell/mesoblast	cesium-137		8.3			References: Mahdi AH, Cancer Res 2018 Jul 15;78(14):3969-3981
Ovary tumor - malignant	Ovary	cesium-137	8.3				References: Mahdi AH, Cancer Res 2018 Jul 15;78(14):3969-3981
(Unspecified organ) tumor	(Unspecified organ)	cesium-137			92		References: Mahdi AH, Cancer Res 2018 Jul 15;78(14):3969-3981

Models