Strain SummaryC57BL/6-Braftm1Mmcm/+Lgr5tm1(cre/ERT2)Cle/+

Strain Name

C57BL/6-Braftm1Mmcm/+Lgr5tm1(cre/ERT2)Cle/+

Strain Type(s)

targeted mutation (conditional)  •  targeted mutation (knock-in)

Strain Synonym(s)

BL  •  BRAFF-V600ELgr5tm1(Cre/ERT2)Cle

Description

Heterozygous Braf, Lgr mice on a C57BL/6 background with contribution from 129P2/OlaHsd.

Strain Genetics

Lgr5tm1(cre/ERT2)Cle / Lgr5+
Braftm1Mmcm / Braf+

Models

1 unique models displayed. A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.
Frequency
Model Name Organ Affected Tumor Inducing Agent(s) Female Male Mixed Pop. Unspecified Additional Information Model Details
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Bacteroides fragilis

0

References: DeStefano Shields CE, Cancer Discov 2021 Feb 25;():