Model DetailsSkin - Dorsal region tumor

Model Name

Skin - Dorsal region tumor

Strain

FVB/NTac-Tg(Hba-x-v-Ha-ras)TG.ACLed

Tumor Inducing Agent(s)

Chemical/Drug : 12-O-tetradecanoylphorbol-13-acetate (TPA)

Tumor Synonyms

dermal tumor  •  skin tumor

Strain Synonyms

FVB/N-TgN(TG.AC)#Led  •  FVB/N-Tg(TG.AC)#Led  •  FVB/N-Tg(Hba-x-v-Ha-ras)TG.ACLed  •  v-Ha-ras  •  hemizygous Tg.AC  •  Tg.AC  •  FVB/NfBR-[Tg]v Ha ras  •  Tg.AC hemizygous  •  TG.AC  •  FVB/NTac-Tg(v-Ha-ras)TG.ACLed
Organ Affected Sex Frequency Age Of Detection Additional Information Expand all Collapse all Reference
Skin - Dorsal region Male

100%

(14 of 14 mice)
19-20 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Age of Onset

    ~15-16 weeks

Eastin WC, Toxicol Pathol 2001;29 Suppl():60-80
Skin - Dorsal region Female

100%

(15 of 15 mice)
19-20 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Age of Onset

    ~15-16 weeks

Eastin WC, Toxicol Pathol 2001;29 Suppl():60-80
Skin - Dorsal region Mixed Population

96.7%

(29 of 30 mice)
35-36 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Age of Onset

    ~14-15 weeks

Eastin WC, Toxicol Pathol 2001;29 Suppl():60-80
Skin - Dorsal region Male

33.3%

(5 of 15 mice)
35-36 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Age of Onset

    ~15-17 weeks

Eastin WC, Toxicol Pathol 2001;29 Suppl():60-80
Skin - Dorsal region Female

40%

(6 of 15 mice)
35-36 weeks
  • Treatment Notes
  • Notes

    Reproductive Status: reproductive status not specified

  • Age of Onset

    ~16-17 weeks

Eastin WC, Toxicol Pathol 2001;29 Suppl():60-80