Model DetailsLeukocyte - Myelocyte (Granulocyte) hyperplasia(Spleen)
Model Name |
Leukocyte - Myelocyte (Granulocyte) hyperplasia (Spleen) | Strain |
(C57BL/6JfC3Hf/Nctr x BALB/cStCrlfC3Hf/Nctr)F2 |
Tumor Inducing Agent(s) |
None (spontaneous) |
Tumor Synonyms |
granulopoiesis • granulopoiesis of spleen • granulocytic hyperplastic lesion • "increase in the granulopoietic activity" |
Strain Synonyms |
F2 hybrid stock • momohybrid cross • [(C57BL/6JfC3Hf/Nctr x BALB/cStCrlfC3Hf/Nctr)F1] x [(C57BL/6JfC3Hf/Nctr x BALB/cStCrlfC3Hf/Nctr)F1] • F1 females x F1 males • F2 Cross • F-1 females x F-1 males |
| Organ Affected | Sex | Frequency | Age Of Detection | Additional Information Expand all Collapse all | Reference |
|---|---|---|---|---|---|
| Spleen | Male |
0% (0 of 7 mice) |
<6 months |
|
Frith CH, J Gerontol 1981 Sep;36(5):534-45 |
| Spleen | Female |
0% (0 of 8 mice) |
<6 months |
|
Frith CH, J Gerontol 1981 Sep;36(5):534-45 |
| Spleen | Male |
6.3% (4 of 63 mice) |
6-12 months |
|
Frith CH, J Gerontol 1981 Sep;36(5):534-45 |
| Spleen | Female |
0% (0 of 57 mice) |
6-12 months |
|
Frith CH, J Gerontol 1981 Sep;36(5):534-45 |
| Spleen | Male |
1.4% (1 of 69 mice) |
12-18 months |
|
Frith CH, J Gerontol 1981 Sep;36(5):534-45 |
| Spleen | Female |
0% (0 of 58 mice) |
12-18 months |
|
Frith CH, J Gerontol 1981 Sep;36(5):534-45 |
| Spleen | Male |
1.8% (3 of 169 mice) |
>18 months |
|
Frith CH, J Gerontol 1981 Sep;36(5):534-45 |
| Spleen | Female |
8.3% (16 of 193 mice) |
>18 months |
|
Frith CH, J Gerontol 1981 Sep;36(5):534-45 |