Pathology Image Detail

Caption

This higher magnification allows to better visualize the glandular features of this neoplasm. The glandular structures are lined by a one cell-thick cuboidal to low columnar epithelium. Neoplastic cells are cuboidal to low columnar, with indistinct cell borders, and a moderate amount of amphophilic cytoplasm which often contains numerous coalescing and optically empty vacuoles (lipids), and occasionally a few acidophilic droplets. The nucleus is basal, oval to round, small to medium-sized, and hyperchromatic. Anisokaryosis and anisocytosis are mild. Proteinaceous secretions occasionally moderately expand the lumen of some glands.

Description

Mammary gland, adenocarcinoma, glandular, acinar, papillary, secretory

Age at Necropsy

162 days

Contributor

Mikaelian I (J:94320)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:25481
Tumor Name
Mammary gland • adenocarcinoma - mixed
Treatment Type
None (spontaneous)
Tumor Synonyms
mammary gland, adenocarcinoma, glandular, acinar, papillary, secretory
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94320

Strain

Strain
C3H/HeJ
Strain Types
inbred
Strain Synonyms
C3H/HeJ-MTV+
C3H The Jackson Laboratory
C3H/HeJ, H-2k
C3H
C3H/He
C3H/HeJ MMTV-
C3H Heston
C3
C3H/HeJ mtv+
MTV+
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
162 days