Mouse Tumor Biology Database (MTB)
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Last Database Update
2018-06-17
MTB 3.0
 
Help Strain Tumor Overview
Collapsed View
 
Strain
C3H/HeJ
Strain Synonyms C3  •  C3H  •  C3H/He  •  C3H/HeJ, H-2k  •  C3H/HeJ MMTV-  •  C3H/HeJ mtv+  •  C3H/HeJ-MTV+  •  C3H Heston  •  C3H The Jackson Laboratory
Strain Tumor Overview Expanded View
Tumors 171 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records
Frequency Range
Adipose tissue - White lipoma Adipose tissue - White None (spontaneous) 2 0
Adipose tissue lipoma Peritoneal cavity None (spontaneous) 2 0
Adipose tissue lipoma - pedunculated Adipose tissue None (spontaneous) 2 0
Adrenal gland - Cortex adenoma Adrenal gland - Cortex None (spontaneous) 8 0 - high
Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla None (spontaneous) 2 0
Adrenal gland - Subcapsular cell hyperplasia - spindle cell Adrenal gland - Subcapsular cell None (spontaneous) 2 moderate - high
Adrenal gland hyperplasia - nodular Adrenal gland None (spontaneous) 2 0
Adrenal gland hyperplasia - spindle cell Adrenal gland None (spontaneous) 4 observed
Adrenal gland tumor - carcinoid Adrenal gland None (spontaneous) 2 0
Blood vessel hemangioma Lymph node None (spontaneous) 1 observed
Blood vessel hemangioma Blood vessel None (spontaneous) 2 0
Blood vessel hemangioma Uterus None (spontaneous) 1 0
Blood vessel hemangiosarcoma Blood vessel None (spontaneous) 2 0
Blood vessel hemangiosarcoma Liver None (spontaneous) 2 0
Blood vessel hemangiosarcoma Muscle - Striated - Skeletal None (spontaneous) 2 0
Bone hyperplasia Bone None (spontaneous) 2 0
Bone lesion - fibro-osseous Bone None (spontaneous) 11 0 - 7.69
Epididymis cyst Epididymis None (spontaneous) 1 0
Erythrocyte leukemia - erythroleukemia Spleen None (spontaneous) 2 0
Erythrocyte neoplasm Erythrocyte None (spontaneous) 2 0
Esophagus hyperplasia Esophagus None (spontaneous) 2 0
Eye - Harderian gland adenocarcinoma Eye - Harderian gland None (spontaneous) 1 0.3
Eye - Harderian gland adenoma - acinar Eye - Harderian gland None (spontaneous) 1 1.4
Eye - Harderian gland adenoma - cystic Eye - Harderian gland None (spontaneous) 1 0.3
Eye - Harderian gland adenoma - cystic papillary Eye - Harderian gland None (spontaneous) 1 0.3
Eye - Harderian gland adenoma - papillary Eye - Harderian gland None (spontaneous) 1 1.4
Eye - Harderian gland tumor Eye - Harderian gland None (spontaneous) 1 3.8
Forestomach hyperplasia - papillary Forestomach None (spontaneous) 2 0
Forestomach papilloma Forestomach None (spontaneous) 2 0
Gallbladder cyst Gallbladder None (spontaneous) 2 0
Gallbladder hyperplasia Gallbladder None (spontaneous) 2 0
Gallbladder hyperplasia - papillary Gallbladder None (spontaneous) 2 0
Intestine - Large Intestine - Cecum hyperplasia Intestine - Large Intestine - Cecum Chemical/Drug 1 observed
Intestine - Large Intestine - Cecum hyperplasia Intestine - Large Intestine - Cecum None (spontaneous) 2 0
Intestine - Large Intestine - Colon adenocarcinoma Intestine - Large Intestine - Colon Chemical/Drug 1 0
Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon None (spontaneous) 2 0
Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon Chemical/Drug 1 observed
Intestine - Large Intestine - Colon dysplasia - high grade Intestine - Large Intestine - Colon Chemical/Drug 1 0
Intestine - Large Intestine - Colon dysplasia - low grade Intestine - Large Intestine - Colon Chemical/Drug 1 observed
Intestine - Large Intestine - Colon hyperplasia Intestine - Large Intestine - Colon Chemical/Drug 2 observed
Intestine - Large Intestine - Colon lesion Intestine - Large Intestine - Colon Chemical/Drug 1 observed
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Chemical/Drug 2 observed - 100
Intestine - Large Intestine tumor Intestine - Large Intestine Chemical/Drug 1 100
Intestine - Small Intestine - Brunner's gland adenoma Intestine - Small Intestine - Brunner's gland None (spontaneous) 2 0
Intestine - Small Intestine - Brunner's gland hyperplasia Intestine - Small Intestine - Brunner's gland None (spontaneous) 2 0
Intestine - Small Intestine - Duodenum adenoma Intestine - Small Intestine - Duodenum None (spontaneous) 3 0 - observed
Intestine - Small Intestine - Duodenum cyst Intestine - Small Intestine - Duodenum None (spontaneous) 2 0
Intestine - Small Intestine - Duodenum hyperplasia Intestine - Small Intestine - Duodenum None (spontaneous) 3 0 - observed
Intestine - Small Intestine - Duodenum polyp Intestine - Small Intestine - Duodenum None (spontaneous) 2 0
Intestine - Small Intestine - Ileum polyp Intestine - Small Intestine - Ileum None (spontaneous) 2 0
Intestine - Small Intestine - Jejunum hyperplasia Intestine - Small Intestine - Jejunum None (spontaneous) 2 0
Intestine - Small Intestine - Jejunum polyp Intestine - Small Intestine - Jejunum None (spontaneous) 3 0 - low
Kidney adenoma Kidney None (spontaneous) 2 0
Kidney cyst Kidney None (spontaneous) 1 observed
Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell tumor Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell None (spontaneous) 2 0
Leukocyte - Lymphocyte leukemia - lymphocytic Leukocyte - Lymphocyte None (spontaneous) 3 0
Leukocyte - Lymphocyte lymphoma Leukocyte - Lymphocyte Chemical/Drug 1 9.09
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte None (spontaneous) 2 0
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Spleen None (spontaneous) 2 0
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Eye - Eyelid None (spontaneous) 2 0
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Lymph node None (spontaneous) 4 0
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Skin None (spontaneous) 2 0
Leukocyte - Myelocyte (Granulocyte) hyperplasia Bone marrow None (spontaneous) 2 0
Leukocyte - Myelocyte (Granulocyte) tumor - malignant Leukocyte - Myelocyte (Granulocyte) Chemical/Drug 1 0
Leukocyte leukemia Leukocyte Virus 4 40 - 100
Leukocyte lymphoma Leukocyte None (spontaneous) 2 0
Liver - Bile duct adenoma Liver - Bile duct None (spontaneous) 2 0
Liver - Bile duct hyperplasia Liver - Bile duct None (spontaneous) 2 0
Liver adenoma Liver Chemical/Drug 1 observed
Liver foci - acidophilic Liver None (spontaneous) 1 observed
Liver hepatocellular adenoma Liver None (spontaneous) 2 observed
Liver hepatocellular adenoma Liver Chemical/Drug 1 observed
Liver hepatocellular carcinoma Liver None (spontaneous) 1 observed
Liver hepatocellular carcinoma Liver Chemical/Drug 1 observed
Liver hepatocellular tumor Liver Chemical/Drug 1 observed
Liver hepatoma Liver None (spontaneous) 4 0 - 21
Liver preneoplastic lesion Liver Chemical/Drug 1 observed
Liver tumor Liver None (spontaneous) 3 observed - 60
Liver tumor Liver Chemical/Drug 3 observed
Lung adenoma Lung Chemical/Drug 5 0 - 10
Lung adenoma Lung None (spontaneous) 6 0
Lung carcinoma Lung Chemical/Drug 2 0
Lung carcinoma Lung None (spontaneous) 1 0
Lung hyperplasia Lung None (spontaneous) 3 0 - observed
Lung hyperplasia Lung Chemical/Drug 1 observed
Lung papilloma Lung None (spontaneous) 1 0
Lung papilloma Lung Chemical/Drug 1 0
Lung tumor Lung None (spontaneous) 8 0 - 25
Lung tumor Lung Chemical/Drug 6 0 - 97
Lymph node cyst Lymph node None (spontaneous) 3 0 - observed
Lymph node hyperplasia Reticulocyte None (spontaneous) 2 0
Mammary gland adenocarcinoma Mammary gland None (spontaneous) 20 observed - 95
Mammary gland adenocarcinoma - acinar Mammary gland None (spontaneous) 11 observed
Mammary gland adenocarcinoma - microacinar Mammary gland Virus 1 observed
Mammary gland adenocarcinoma - mixed Mammary gland None (spontaneous) 7 observed
Mammary gland adenocarcinoma - papillary Mammary gland None (spontaneous) 2 observed
Mammary gland adenocarcinoma - papillary Mammary gland Virus 1 observed
Mammary gland adenocarcinoma - tubular Mammary gland None (spontaneous) 3 observed
Mammary gland adenocarcinoma - tubulostromal Mammary gland None (spontaneous) 1 observed
Mammary gland adenocarcinoma - type B Mammary gland Virus 1 observed
Mammary gland adenocarcinoma - type P Mammary gland Virus 1 observed
Mammary gland carcinoma - mixed Mammary gland None (spontaneous) 1 observed
Mammary gland hyperplasia - alveolar Mammary gland Virus 1 observed
Mammary gland tumor Mammary gland Virus 4 observed - 100
Mammary gland tumor Mammary gland None (spontaneous) 4 observed - 100.0
Mesodermal cell/mesoblast myxosarcoma Muscle - Striated - Skeletal None (spontaneous) 2 0
Mesodermal cell/mesoblast sarcoma Peritoneal cavity None (spontaneous) 2 0
Mesodermal cell/mesoblast sarcoma Seminal vesicle None (spontaneous) 1 0
Mesodermal cell/mesoblast sarcoma Stomach - Glandular None (spontaneous) 2 0
Mesodermal cell/mesoblast sarcoma Urinary bladder None (spontaneous) 2 0
Mesodermal cell/mesoblast sarcoma - stromal Uterus - Endometrium - Stroma None (spontaneous) 1 0
Mouth - Oral mucosa cyst Mouth - Oral mucosa None (spontaneous) 2 0
Muscle - Smooth leiomyoma Vagina None (spontaneous) 1 0
Muscle - Smooth leiomyosarcoma Intestine - Large Intestine - Cecum None (spontaneous) 2 0
Muscle - Smooth leiomyosarcoma Muscle - Smooth None (spontaneous) 2 0
Muscle - Striated - Skeletal rhabdomyosarcoma Muscle - Striated - Skeletal None (spontaneous) 2 0
Muscle - Striated - Skeletal rhabdomyosarcoma - pleomorphic Muscle - Striated - Skeletal None (spontaneous) 1 0
Myoepithelial cell myoepithelioma Myoepithelial cell None (spontaneous) 1 observed
Myoepithelial cell myoepithelioma Lung None (spontaneous) 2 0
Myoepithelial cell myoepithelioma Mammary gland None (spontaneous) 2 0
Nail squamous cell carcinoma Nail None (spontaneous) 2 0
Ovary - Follicle cyst - follicular Ovary - Follicle None (spontaneous) 1 very high
Ovary - Granulosa cell tumor - granulosa cell Ovary - Granulosa cell None (spontaneous) 1 0
Ovary - Luteal cell tumor Ovary - Luteal cell None (spontaneous) 1 low
Ovary - Theca cell thecoma Ovary - Theca cell None (spontaneous) 1 observed
Ovary adenoma Ovary None (spontaneous) 2 0 - observed
Ovary cyst Ovary None (spontaneous) 2 observed
Ovary cyst - bursal Ovary None (spontaneous) 1 0
Ovary hyperplasia - epithelial Ovary None (spontaneous) 1 0
Ovary tumor - tubulostromal Ovary None (spontaneous) 1 0
PNS - Nerve sheath tumor Ear None (spontaneous) 2 0
PNS - Nerve sheath tumor Skin None (spontaneous) 2 0
Pancreas - Duct adenoma Pancreas - Duct None (spontaneous) 2 0
Pancreas - Islet of Langerhans hyperplasia Pancreas - Islet of Langerhans None (spontaneous) 4 observed
Pituitary gland adenoma Pituitary gland None (spontaneous) 1 observed
Prostate gland - Anterior lobe adenocarcinoma Prostate gland - Anterior lobe None (spontaneous) 1 0
Skin - Ear melanoma Skin - Ear Other 1 observed
Skin - Epidermis - Basal cell carcinoma Skin - Epidermis - Basal cell None (spontaneous) 2 0
Skin - Epidermis cyst - inclusion Skin - Epidermis None (spontaneous) 2 0
Skin - Vibrissa squamous cell carcinoma in situ Skin - Vibrissa None (spontaneous) 2 0
Skin choristoma Skin None (spontaneous) 1 observed
Skin gland - Sweat gland hyperplasia Ear - Outer ear - Ear canal None (spontaneous) 2 0
Skin hyperplasia - epithelial Ear None (spontaneous) 2 0
Skin hyperplasia - epithelial Eye - Eyelid None (spontaneous) 2 0
Skin tumor Skin Chemical/Drug 1 67
Spleen hyperplasia Spleen None (spontaneous) 1 observed
Stomach - Glandular adenoma Stomach - Glandular None (spontaneous) 2 0
Stomach - Glandular cyst Stomach - Glandular None (spontaneous) 2 0
Stomach - Glandular cyst - glandular Stomach - Glandular None (spontaneous) 2 0
Stomach - Glandular hyperplasia Stomach - Glandular None (spontaneous) 2 0
Stomach - Glandular hyperplasia - adenomatous Stomach - Glandular None (spontaneous) 2 0
Stomach - Glandular polyp Stomach - Glandular None (spontaneous) 2 0
Stomach papilloma Stomach None (spontaneous) 1 observed
Testis - Leydig cell (Interstitial cell) cyst Testis - Leydig cell (Interstitial cell) None (spontaneous) 1 0
Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell) None (spontaneous) 1 0
Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell) None (spontaneous) 1 0
Thyroid gland - Follicular cell cyst Thyroid gland - Follicular cell None (spontaneous) 2 observed
Thyroid gland adenoma Thyroid gland None (spontaneous) 1 observed
Thyroid gland hyperplasia - cystic Thyroid gland None (spontaneous) 2 low - moderate
Ureter - Transitional cell hyperplasia Ureter - Transitional cell None (spontaneous) 2 0
Ureter hyperplasia Muscle - Smooth None (spontaneous) 2 0
Ureter polyp Ureter None (spontaneous) 2 0
Urinary bladder - Transitional cell atypia Urinary bladder - Transitional cell None (spontaneous) 2 0
Urinary bladder papilloma Urinary bladder None (spontaneous) 2 0
Uterus - Endometrium hyperplasia - cystic Uterus - Endometrium None (spontaneous) 2 0 - observed
Uterus adenoma Uterus None (spontaneous) 1 0
Uterus fibropapilloma Uterus None (spontaneous) 1 0
Uterus hyperplasia - glandular Uterus Virus 1 observed
Vagina papilloma Vagina None (spontaneous) 1 0
Vagina polyp Vagina None (spontaneous) 1 observed
Vulva squamous cell carcinoma Vulva None (spontaneous) 1 0
Other Database Links
Additional information about these mice:
Mouse Phenome Database (MPD) http://phenome.jax.org/db/q?rtn=strains/details&strainid=6
Festing's List of Inbred Strains http://www.informatics.jax.org/external/festing/mouse/docs/C3H.shtml
JAX Mice http://jaxmice.jax.org/strain/000659.html