Pathology Image Detail

Caption

Colon - Normal tissue. There is intense cytoplasmic labelling for alpha smooth muscle actin of smooth muscle fibers of the muscularis mucosae and of the wall of the colon (antibody diluted at 1:6,000, tissue fixed in Bouin's solution).

Description

Intestine - Smooth muscle - normal tissue.

Age at Necropsy

unknown

Contributor

Mikaelian I (J:94310)

Pathologist

Mikaelian I (J:94310)

Method

IHC for alpha smooth muscle actin
Image Probes

Type: antibody

Name
anti-alpha smooth muscle actin (A2547)
Target
alpha-smooth muscle actin, N-terminus
Supplier
Sigma-Aldrich
Notes
Monoclonal anti-Alpha Smooth Muscle Actin antibody produced in mouse (raised against N-terminal synthetic decapeptide of alpha-smooth muscle actin). The antibody (also known as anti-a-Sm-1) is specific for the single isoform of alpha-smooth muscle actin.

Model

MMHC ID
MTB:27648
Tumor Name
Intestine • normal tissue (control)
Treatment Type
None (spontaneous)
Tumor Synonyms
intestine, normal tissue
Organ Affected
Intestine
Frequency
not applicable
Reference
J:94310

Strain

Strain
C57BL/6J
Strain Types
inbred
Strain Synonyms
wild-type C57BL/6J
C57Bl/6J
p53+/+
C57BL/6 from Jackson Laboratory
C57BL/6
B6
C57/Bl6
C57
C57BL/6J (F129+51)
C57 black subline 6
B/6
Bl/6
C57BL/6J wild-type
WT
Black 6
C57 Black
wild type
C57BL/6J+/+
p53 wild-type (+/+)
C57BL6/J
C57BL/6J, H-2b
C57/B16
wild-type
C57BL
B6 WT
wild-type (WT)
WT-Control
WT-CR
C57/Bl 6J
C57/Bl
p21+/+p27+/+
control
Ctr
C57BL/6J (UW)
B6J
C57BL/6J inbred WT
C57 BL/6
Wild-type (WT) C57BL/6J
Strain Sex
Unspecified
Reproductive Status
reproductive status not specified
Age of Detection
unknown