Strain SummaryC57BL/6J

Strain Name	C57BL/6J
Strain Type(s)	inbred
Strain Synonym(s)	B6 • B/6 • B6J • B6 WT • Bl/6 • Black 6 • C57 • C57/B16 • C57/Bl • C57BL • C57/Bl6 • C57 BL/6 • C57BL/6 • C57BL/6 from Jackson Laboratory • C57/Bl 6J • C57Bl/6J • C57BL6/J • C57BL/6J (F₁₂₉₊₅₁) • C57BL/6J, H-2^b • C57BL/6J inbred WT • C57BL/6J^+/+ • C57BL/6J (UW) • C57BL/6J wild-type • C57 Black • C57 black subline 6 • control • Ctr • p53+/+ • p53 wild-type (+/+) • p21+/+p27+/+ • wild type • wild-type • wild-type C57BL/6J • wild-type (WT) • Wild-type (WT) C57BL/6J • WT • WT-Control • WT-CR
Strain Links	• Mouse Phenome Database (MPD) • Festing's List of Inbred Strains • JAX Mice
Strain Genetics	List all models in MMHCdb carrying the Kras^b allele Kras^b / Kras^b
	List all models in MMHCdb carrying the H2^b allele H2^b / H2^b

Models
580 unique models displayed. *A model is a set of tumors that share the same tumor name, organ(s) affected, and treatment type for a specific strain.*
			Frequency
Model Name	Organ Affected	Tumor Inducing Agent(s)	Female	Male	Mixed Pop.	Unspecified	Additional Information	Model Details
Adipose tissue - White lipoma	Adipose tissue - White		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Adipose tissue lipoma	Scrotum			observed			References: Sundberg J, MGI Direct Data Submission 2007;(): 5 pathology image(s)
Adipose tissue lipoma	Peritoneal cavity		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Adipose tissue lipoma - pedunculated	Adipose tissue		0	very low			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Adrenal gland - Cortex adenoma	Adrenal gland - Cortex		0 - observed	0			References: Sundberg J, MGI Direct Data Submission 2007;(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Adrenal gland - Cortex normal tissue (control)	Adrenal gland - Cortex					not applicable	References: Mikaelian I, Personal Communication 2004;(): 2 pathology image(s)
Adrenal gland - Medulla normal tissue (control)	Adrenal gland - Medulla		not applicable			not applicable	References: Mikaelian I, Personal Communication 2004;(): 6 pathology image(s)
Adrenal gland - Medulla pheochromocytoma	Adrenal gland - Medulla		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Adrenal gland - Medulla pheochromocytoma - malignant	Adrenal gland - Medulla				1		References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():
Adrenal gland - Subcapsular cell hyperplasia	Adrenal gland - Subcapsular cell		0 - observed	0			References: Mikaelian I, Personal Communication 2004;(): ⋅ Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112 1 pathology image(s)
Adrenal gland - Subcapsular cell hyperplasia	Adrenal gland - Subcapsular cell	calorie restricted	0 - 2.0	0			References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Adrenal gland - Subcapsular cell hyperplasia - spindle cell	Adrenal gland - Subcapsular cell		moderate	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Adrenal gland hyperplasia - nodular	Adrenal gland		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Adrenal gland hyperplasia - spindle cell	Adrenal gland		observed	observed			References: Sundberg J, MGI Direct Data Submission 2007;():
Adrenal gland tumor - carcinoid	Adrenal gland		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Blood vessel - Aorta metaplasia - cartilaginous	Blood vessel - Aorta					0	References: Verschoyle RD, Toxicol Pathol 2004 Jan-Feb;32(1):22-5
Blood vessel hemangioma	Liver		2	6			References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10
Blood vessel hemangioma	Blood vessel		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Blood vessel hemangioma	Spleen				1		References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():
Blood vessel hemangioma	Uterus		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Blood vessel hemangioma - capillary	Blood vessel		observed				References: Booth CJ, Lab Anim Sci 1995 Oct;45(5):497-502
Blood vessel hemangioma - capillary	Liver		observed				References: Booth CJ, Lab Anim Sci 1995 Oct;45(5):497-502
Blood vessel hemangioma - cavernous	Ovary		observed				References: Sundberg J, MGI Direct Data Submission 2007;(): 5 pathology image(s)
Blood vessel hemangioma - cavernous	Spleen			observed			References: Sundberg J, MGI Direct Data Submission 2007;(): 5 pathology image(s)
Blood vessel hemangiosarcoma	Spleen		0	4.0	observed		References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8 ⋅ Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112 ⋅ Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():
Blood vessel hemangiosarcoma	Liver		0 - observed	0 - 2	observed		References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10 ⋅ McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8 ⋅ Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112 ⋅ Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1(): ⋅ Sundberg J, MGI Direct Data Submission 2007;(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Blood vessel hemangiosarcoma	Spleen	calorie restricted	0	0			References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8 ⋅ Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Blood vessel hemangiosarcoma	Liver	calorie restricted	0	0			References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8 ⋅ Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Blood vessel hemangiosarcoma	Blood vessel		0	0	4		References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80 ⋅ Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Blood vessel hemangiosarcoma	Blood vessel	cesium-137	0	0			References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80
Blood vessel hemangiosarcoma	Uterus		observed				References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():
Blood vessel hemangiosarcoma	Ovary		observed				References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():
Blood vessel hemangiosarcoma	Skin				observed		References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():
Blood vessel hemangiosarcoma	Muscle - Striated - Skeletal		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Blood vessel neoplasm	Blood vessel		2	4			References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105
Blood vessel normal tissue (control)	Blood vessel					not applicable	References: Mikaelian I, Personal Communication 2004;(): 5 pathology image(s)
Blood vessel tumor	(Unspecified organ)	(see notes regarding diet)			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Bone - Vertebral column - Vertebra osteosarcoma	Bone - Vertebral column - Vertebra				1		References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():
Bone - Vertebral column - Vertebra osteosarcoma - chondroblastic	Bone - Vertebral column - Vertebra		observed				References: Mikaelian I, Personal Communication 2004;(): 7 pathology image(s)
Bone hyperplasia	Bone		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Bone lesion - fibro-osseous	Bone		0 - 13.33	0	0 - 6.9		References: Berndt A, Exp Mol Pathol 2015 Nov 14;(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Bone marrow normal tissue (control)	Bone marrow					not applicable	References: Mikaelian I, Personal Communication 2004;(): 6 pathology image(s)
Bone neoplasm	Bone		2	0			References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105
Bone osteosarcoma	Bone			observed		observed	References: Mikaelian I, Personal Communication 2002;(): ⋅ Mikaelian I, Personal Communication 2003;(): 1 pathology image(s)
CNS - Brain - Choroid plexus normal tissue (control)	CNS - Brain - Choroid plexus					not applicable	References: Mikaelian I, Personal Communication 2003;(): ⋅ Mikaelian I, Personal Communication 2004;(): 4 pathology image(s)
CNS - Brain - Ependyma normal tissue (control)	CNS - Brain - Ependyma					not applicable	References: Mikaelian I, Personal Communication 2004;(): 1 pathology image(s)
CNS - Brain - Glial cell normal tissue (control)	CNS - Brain - Glial cell					not applicable	References: Mikaelian I, Personal Communication 2003;(): 3 pathology image(s)
CNS - Brain - Neuron normal tissue (control)	CNS - Brain - Neuron					not applicable	References: Mikaelian I, Personal Communication 2004;(): 2 pathology image(s)
CNS - Brain glioma	CNS - Brain					0	References: Harris MA, Cancer Res 2008 Dec 15;68(24):10051-9
CNS - Brain normal tissue (control)	CNS - Brain					not applicable	References: Mikaelian I, Personal Communication 2003;(): ⋅ Mikaelian I, Personal Communication 2004;(): 3 pathology image(s)
CNS - Spinal cord normal tissue (control)	CNS - Spinal cord					not applicable	References: Mikaelian I, Personal Communication 2004;(): 1 pathology image(s)
Connective tissue - Cartilage - Articular hyperplasia	Limb - Hindlimb					0	References: Verschoyle RD, Toxicol Pathol 2004 Jan-Feb;32(1):22-5
Connective tissue - Cartilage hyperplasia	Bone - Sternum					0	References: Verschoyle RD, Toxicol Pathol 2004 Jan-Feb;32(1):22-5
Connective tissue - Cartilage hyperplasia	Ear - Outer ear					0	References: Verschoyle RD, Toxicol Pathol 2004 Jan-Feb;32(1):22-5
Connective tissue - Fibroblast fibrosarcoma	Connective tissue - Fibroblast				4		References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():
Connective tissue - Fibroblast fibrosarcoma	Uterus		observed				References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():
Connective tissue - Fibroblast fibrosarcoma	Skin				observed		References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():
Connective tissue - Fibroblast fibrosarcoma	Perirenal tissue				observed		References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():
Connective tissue - Fibroblast fibrosarcoma	Ear				observed		References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():
Dendritic cell normal tissue (control)	Lymph node					not applicable	References: Mikaelian I, Personal Communication 2004;(): 1 pathology image(s)
Epididymis cyst	Epididymis			0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Epididymis normal tissue (control)	Epididymis			not applicable			References: Mikaelian I, Personal Communication 2004;(): 1 pathology image(s)
Erythrocyte leukemia - erythroleukemia	Spleen		0	0			References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8 ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Erythrocyte leukemia - erythroleukemia	Liver		0				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Erythrocyte leukemia - erythroleukemia	Spleen	calorie restricted	3.3				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Erythrocyte leukemia - erythroleukemia	Liver	calorie restricted	3.3				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Erythrocyte neoplasm	Erythrocyte		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Esophagus dysplasia	Esophagus	Propylene glycol ⋅ 4-nitroquinoline-1-oxide (4NQO)	observed				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Esophagus hyperplasia	Esophagus		0	0			References: Fong LY, Cancer Res 2003 Jan 1;63(1):186-95 ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Esophagus hyperplasia	Esophagus	zinc-deficient		observed			References: Fong LY, Cancer Res 2003 Jan 1;63(1):186-95
Esophagus hyperplasia	Esophagus	Propylene glycol	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Esophagus hyperplasia	Esophagus	Propylene glycol ⋅ 4-nitroquinoline-1-oxide (4NQO)	observed - 100				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Esophagus lesion	Esophagus	Propylene glycol	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Esophagus lesion	Esophagus	Propylene glycol ⋅ 4-nitroquinoline-1-oxide (4NQO)	100				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Esophagus normal tissue (control)	Esophagus					not applicable	References: Mikaelian I, Personal Communication 2002;(): ⋅ Mikaelian I, Personal Communication 2004;(): 9 pathology image(s)
Esophagus papilloma	Esophagus	Propylene glycol	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Esophagus papilloma	Esophagus	Propylene glycol ⋅ 4-nitroquinoline-1-oxide (4NQO)	100				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Esophagus squamous cell carcinoma	Esophagus	N-amyl-N-methylnitrosoamine (AMN)				observed	References: Kurooka M, Cancer Lett 1998 May 15;127(1-2):55-61
Esophagus squamous cell carcinoma	Esophagus	Propylene glycol	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Esophagus squamous cell carcinoma	Esophagus	Propylene glycol ⋅ 4-nitroquinoline-1-oxide (4NQO)	observed - 100				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Esophagus tumor	Esophagus					0	References: Kurooka M, Cancer Lett 1998 May 15;127(1-2):55-61
Esophagus tumor	Esophagus	N-amyl-N-methylnitrosoamine (AMN)				100	References: Kurooka M, Cancer Lett 1998 May 15;127(1-2):55-61
Esophagus tumor	Esophagus	N-nitrosomethylbenzylamine (NMBA) ⋅ zinc-deficient		0			References: Fong LY, Cancer Res 2003 Jan 1;63(1):186-95
Esophagus tumor	Esophagus	N-nitrosomethylbenzylamine (NMBA)		0			References: Fong LY, Cancer Res 2003 Jan 1;63(1):186-95
Esophagus tumor	Esophagus	Propylene glycol	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Esophagus tumor	Esophagus	Propylene glycol ⋅ 4-nitroquinoline-1-oxide (4NQO)	100				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Eye - Conjunctiva normal tissue (control)	Eye - Conjunctiva					not applicable	References: Mikaelian I, Personal Communication 2004;(): 1 pathology image(s)
Eye - Cornea normal tissue (control)	Eye - Cornea					not applicable	References: Mikaelian I, Personal Communication 2003;(): ⋅ Mikaelian I, Personal Communication 2004;(): 7 pathology image(s)
Eye - Eyelid normal tissue (control)	Eye - Eyelid					not applicable	References: Mikaelian I, Personal Communication 2003;(): 1 pathology image(s)
Eye - Harderian gland adenoma	Eye - Harderian gland			observed			References: Sundberg J, MGI Direct Data Submission 2007;(): 3 pathology image(s)
Eye - Harderian gland neoplasm	Eye - Harderian gland		0	0			References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105
Eye - Retina normal tissue (control)	Eye - Retina					not applicable	References: Mikaelian I, Personal Communication 2004;(): 3 pathology image(s)
Eye normal tissue (control)	Eye					not applicable	References: Mikaelian I, Personal Communication 2002;(): 2 pathology image(s)
Forestomach - Squamocolumnar junction with the glandular stomach tumor	Forestomach - Squamocolumnar junction with the glandular stomach	N-nitrosomethylbenzylamine (NMBA) ⋅ zinc-deficient		13			References: Fong LY, Cancer Res 2003 Jan 1;63(1):186-95
Forestomach - Squamocolumnar junction with the glandular stomach tumor	Forestomach - Squamocolumnar junction with the glandular stomach	N-nitrosomethylbenzylamine (NMBA)		0			References: Fong LY, Cancer Res 2003 Jan 1;63(1):186-95
Forestomach hyperplasia	Forestomach	zinc-deficient		observed			References: Fong LY, Cancer Res 2003 Jan 1;63(1):186-95
Forestomach hyperplasia	Forestomach			0			References: Fong LY, Cancer Res 2003 Jan 1;63(1):186-95
Forestomach hyperplasia - papillary	Forestomach		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Forestomach lesion	Forestomach	Propylene glycol ⋅ 4-nitroquinoline-1-oxide (4NQO)	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Forestomach lesion	Forestomach	Propylene glycol	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Forestomach normal tissue (control)	Forestomach					not applicable	References: Mikaelian I, Personal Communication 2004;(): 1 pathology image(s)
Forestomach papilloma	Forestomach		very low	very low			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Forestomach tumor	Forestomach	N-nitrosomethylbenzylamine (NMBA) ⋅ zinc-deficient		13			References: Fong LY, Cancer Res 2003 Jan 1;63(1):186-95
Forestomach tumor	Forestomach	N-nitrosomethylbenzylamine (NMBA)		0			References: Fong LY, Cancer Res 2003 Jan 1;63(1):186-95
Forestomach tumor	Forestomach	Propylene glycol ⋅ 4-nitroquinoline-1-oxide (4NQO)	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Forestomach tumor	Forestomach	Propylene glycol	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Gallbladder cyst	Gallbladder		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Gallbladder hyperplasia	Gallbladder		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Gallbladder hyperplasia - papillary	Gallbladder		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Gastrointestinal tract tumor	Gastrointestinal tract					0	References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54
Gingiva squamous cell carcinoma - well differentiated	Gingiva		observed				References: Sundberg J, MGI Direct Data Submission 2007;(): 6 pathology image(s)
Heart normal tissue (control)	Heart					not applicable	References: Mikaelian I, Personal Communication 2002;(): ⋅ Mikaelian I, Personal Communication 2004;(): 4 pathology image(s)
Intestine - Large Intestine - Cecum adenoma - flat	Intestine - Large Intestine - Cecum	(see notes regarding diet)			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine - Large Intestine - Cecum hyperplasia	Intestine - Large Intestine - Cecum	dextran sulfate sodium (DSS)			observed		References: Mahler M, Am J Physiol 1998 Mar;274(3 Pt 1):G544-51
Intestine - Large Intestine - Cecum hyperplasia	Intestine - Large Intestine - Cecum		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Intestine - Large Intestine - Colon - Distal adenocarcinoma	Intestine - Large Intestine - Colon - Distal					0	References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54
Intestine - Large Intestine - Colon - Distal adenoma	Intestine - Large Intestine - Colon - Distal					0	References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54
Intestine - Large Intestine - Colon - Distal foci - aberrant crypt (ACF)	Intestine - Large Intestine - Colon - Distal	azoxymethane (AOM)		observed			References: Nambiar PR, Int J Oncol 2003 Jan;22(1):145-50
Intestine - Large Intestine - Colon - Distal tumor	Intestine - Large Intestine - Colon - Distal	azoxymethane (AOM)		0			References: Nambiar PR, Int J Oncol 2003 Jan;22(1):145-50
Intestine - Large Intestine - Colon - Medial adenocarcinoma	Intestine - Large Intestine - Colon - Medial					0	References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54
Intestine - Large Intestine - Colon - Medial adenoma	Intestine - Large Intestine - Colon - Medial					0	References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54
Intestine - Large Intestine - Colon - Proximal adenocarcinoma	Intestine - Large Intestine - Colon - Proximal					0	References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54
Intestine - Large Intestine - Colon - Proximal adenoma	Intestine - Large Intestine - Colon - Proximal					0	References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54
Intestine - Large Intestine - Colon - Proximal tumor	Intestine - Large Intestine - Colon - Proximal	azoxymethane (AOM)		0			References: Nambiar PR, Int J Oncol 2003 Jan;22(1):145-50
Intestine - Large Intestine - Colon adenocarcinoma	Intestine - Large Intestine - Colon	(see notes regarding diet)			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine - Large Intestine - Colon adenoma	Intestine - Large Intestine - Colon		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Intestine - Large Intestine - Colon hyperplasia	Intestine - Large Intestine - Colon	dextran sulfate sodium (DSS)	observed	observed			References: Mahler M, Am J Physiol 1998 Mar;274(3 Pt 1):G544-51
Intestine - Large Intestine - Colon lesion	Intestine - Large Intestine - Colon	Propylene glycol ⋅ 4-nitroquinoline-1-oxide (4NQO)	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Intestine - Large Intestine - Colon lesion	Intestine - Large Intestine - Colon	Propylene glycol	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Intestine - Large Intestine - Colon normal tissue (control)	Intestine - Large Intestine - Colon					not applicable	References: Mikaelian I, Personal Communication 2002;(): ⋅ Mikaelian I, Personal Communication 2004;(): 37 pathology image(s)
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	1,2-dimethylhydrazine (DMH)				observed	References: Rosenberg DW, Cancer Lett 1995 Jun 8;92(2):209-14
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	azoxymethane (AOM)				observed	References: Shattuck-Brandt RL, Gastroenterology 2000 Feb;118(2):337-45 ⋅ Shattuck-Brandt RL, Mol Carcinog 1999 Mar;24(3):177-87
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	troglitazone			0		References: Saez E, Nat Med 1998 Sep;4(9):1058-61
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	dextran sulfate sodium (DSS) ⋅ azoxymethane (AOM)			100		References: Van Der Kraak L, Mamm Genome 2016 Jun;27(5-6):213-24
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	AIN-76A			0 - 6.67		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	New western diet (NWD) TD.96096			0 - 26.67		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	New western diet (NWD) TD.96096 ⋅ vitamin D₃ (1alpha,25-(OH)₂-D₃) (VD₃) ⋅ Calcium-enriched			0 - 4.55		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	New western diet (NWD) TD.96096 ⋅ Folic acid-enriched			0 - 27.78		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	choline-enriched ⋅ New western diet (NWD) TD.96096			5.56 - 10		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	methionine-enriched ⋅ New western diet (NWD) TD.96096			11.11 - 18.75		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	New western diet (NWD) TD.96096 ⋅ high fiber			0 - 29.41		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	Propylene glycol ⋅ 4-nitroquinoline-1-oxide (4NQO)	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	Propylene glycol	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Intestine - Large Intestine - Colon tumor	Intestine - Large Intestine - Colon	Bacteroides fragilis			0		References: DeStefano Shields CE, Cancer Discov 2021 Feb 25;():
Intestine - Large Intestine adenocarcinoma	Intestine - Large Intestine					0	References: Berg DJ, J Clin Invest 1996 Aug 15;98(4):1010-20
Intestine - Large Intestine tumor	Intestine - Large Intestine	dextran sulfate sodium (DSS) ⋅ azoxymethane (AOM)			100		References: Van Der Kraak L, Mamm Genome 2016 Jun;27(5-6):213-24
Intestine - Small Intestine - Brunner's gland adenoma	Intestine - Small Intestine - Brunner's gland		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Intestine - Small Intestine - Brunner's gland hyperplasia	Intestine - Small Intestine - Brunner's gland		0	0 - observed			References: Sundberg J, MGI Direct Data Submission 2007;(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1(): 5 pathology image(s)
Intestine - Small Intestine - Duodenum adenocarcinoma	Intestine - Small Intestine - Duodenum					0	References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54
Intestine - Small Intestine - Duodenum adenoma	Intestine - Small Intestine - Duodenum		0	0		0	References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1(): ⋅ Yang K, J Exp Zool 1997 Feb 15;277(3):245-54
Intestine - Small Intestine - Duodenum cyst	Intestine - Small Intestine - Duodenum		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Intestine - Small Intestine - Duodenum hyperplasia	Intestine - Small Intestine - Duodenum		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Intestine - Small Intestine - Duodenum lesion	Intestine - Small Intestine - Duodenum	N-[4-(3-chloro-4-fluoro-phenylamino)-quinazolin-6-yl]acrylamide (CFPQA)			observed		References: Ritland SR, Cancer Res 2000 Sep 1;60(17):4678-81
Intestine - Small Intestine - Duodenum normal tissue (control)	Intestine - Small Intestine - Duodenum		not applicable			not applicable	References: Mikaelian I, Personal Communication 2004;(): 14 pathology image(s)
Intestine - Small Intestine - Duodenum polyp	Intestine - Small Intestine - Duodenum		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Intestine - Small Intestine - Ileum adenocarcinoma	Intestine - Small Intestine - Ileum					0	References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54
Intestine - Small Intestine - Ileum adenoma	Intestine - Small Intestine - Ileum					0	References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54
Intestine - Small Intestine - Ileum normal tissue (control)	Intestine - Small Intestine - Ileum			not applicable			References: Paoni NF, Physiol Genomics 2003 Nov 11;15(3):228-35
Intestine - Small Intestine - Ileum polyp	Intestine - Small Intestine - Ileum		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Intestine - Small Intestine - Jejunum adenocarcinoma	Intestine - Small Intestine - Jejunum					0	References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54
Intestine - Small Intestine - Jejunum adenoma	Intestine - Small Intestine - Jejunum					0	References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54
Intestine - Small Intestine - Jejunum hyperplasia	Intestine - Small Intestine - Jejunum		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Intestine - Small Intestine - Jejunum polyp	Intestine - Small Intestine - Jejunum		0	0 - observed			References: Sundberg J, Personal Communication 1997;(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Intestine - Small Intestine adenocarcinoma	Intestine - Small Intestine	(see notes regarding diet)			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine - Small Intestine adenoma - tubular	Intestine - Small Intestine	(see notes regarding diet)			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine - Small Intestine normal tissue (control)	Intestine - Small Intestine					not applicable	References: Mikaelian I, Personal Communication 2002;(): ⋅ Mikaelian I, Personal Communication 2003;(): ⋅ Mikaelian I, Personal Communication 2004;(): 40 pathology image(s)
Intestine - Small Intestine tumor	Intestine - Small Intestine		0				References: Williams JL, Biochem Biophys Res Commun 2004 Jan 16;313(3):784-8
Intestine - Small Intestine tumor	Intestine - Small Intestine	2-(acetyloxy)benzoic acid 4-(nitrooxy methyl)phenyl ester) (NO-ASA)	0				References: Williams JL, Biochem Biophys Res Commun 2004 Jan 16;313(3):784-8
Intestine - Small Intestine tumor	Intestine - Small Intestine	(see notes regarding diet)			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine - Small Intestine tumor	Intestine - Small Intestine	AIN-76A			0 - 26.67		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine - Small Intestine tumor	Intestine - Small Intestine	New western diet (NWD) TD.96096			0 - 26.67		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine - Small Intestine tumor	Intestine - Small Intestine	New western diet (NWD) TD.96096 ⋅ vitamin D₃ (1alpha,25-(OH)₂-D₃) (VD₃) ⋅ Calcium-enriched			5.56 - 15.38		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine - Small Intestine tumor	Intestine - Small Intestine	New western diet (NWD) TD.96096 ⋅ Folic acid-enriched			7.14 - 26.09		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine - Small Intestine tumor	Intestine - Small Intestine	choline-enriched ⋅ New western diet (NWD) TD.96096			10 - 33.33		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine - Small Intestine tumor	Intestine - Small Intestine	methionine-enriched ⋅ New western diet (NWD) TD.96096			11.11 - 25		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine - Small Intestine tumor	Intestine - Small Intestine	New western diet (NWD) TD.96096 ⋅ high fiber			0 - 11.76		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine adenocarcinoma	Intestine	(see notes regarding diet)			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine adenoma	Intestine	(see notes regarding diet)			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine adenoma	Intestine	AIN-76A			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine adenoma	Intestine	New western diet (NWD) TD.96096			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine adenoma	Intestine	New western diet (NWD) TD.96096 ⋅ vitamin D₃ (1alpha,25-(OH)₂-D₃) (VD₃) ⋅ Calcium-enriched			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine adenoma	Intestine	New western diet (NWD) TD.96096 ⋅ Folic acid-enriched			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine adenoma	Intestine	choline-enriched ⋅ New western diet (NWD) TD.96096			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine adenoma	Intestine	methionine-enriched ⋅ New western diet (NWD) TD.96096			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine adenoma	Intestine	New western diet (NWD) TD.96096 ⋅ high fiber			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine adenoma - tubular	Intestine	(see notes regarding diet)			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine carcinoma	Intestine	AIN-76A			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine carcinoma	Intestine	New western diet (NWD) TD.96096			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine carcinoma	Intestine	New western diet (NWD) TD.96096 ⋅ vitamin D₃ (1alpha,25-(OH)₂-D₃) (VD₃) ⋅ Calcium-enriched			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine carcinoma	Intestine	New western diet (NWD) TD.96096 ⋅ Folic acid-enriched			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine carcinoma	Intestine	choline-enriched ⋅ New western diet (NWD) TD.96096			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine carcinoma	Intestine	methionine-enriched ⋅ New western diet (NWD) TD.96096			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine carcinoma	Intestine	New western diet (NWD) TD.96096 ⋅ high fiber			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine carcinoma - invasive	Intestine	(see notes regarding diet)			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine carcinoma - invasive	Intestine	AIN-76A			0		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine carcinoma - invasive	Intestine	methionine-enriched ⋅ New western diet (NWD) TD.96096			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine carcinoma - invasive	Intestine	New western diet (NWD) TD.96096 ⋅ high fiber			2		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine carcinoma - invasive	Intestine	New western diet (NWD) TD.96096 ⋅ vitamin D₃ (1alpha,25-(OH)₂-D₃) (VD₃) ⋅ Calcium-enriched			0		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine carcinoma - invasive	Intestine	New western diet (NWD) TD.96096 ⋅ Folic acid-enriched			0		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine carcinoma - invasive	Intestine	New western diet (NWD) TD.96096			0		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine carcinoma - invasive	Intestine	choline-enriched ⋅ New western diet (NWD) TD.96096			0		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine lesion	Intestine	AIN-76A			0		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine lesion	Intestine	New western diet (NWD) TD.96096			0		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine lesion	Intestine	New western diet (NWD) TD.96096 ⋅ vitamin D₃ (1alpha,25-(OH)₂-D₃) (VD₃) ⋅ Calcium-enriched			0		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine lesion	Intestine	New western diet (NWD) TD.96096 ⋅ Folic acid-enriched			0		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine lesion	Intestine	choline-enriched ⋅ New western diet (NWD) TD.96096			0		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine lesion	Intestine	methionine-enriched ⋅ New western diet (NWD) TD.96096			0		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine lesion	Intestine	New western diet (NWD) TD.96096 ⋅ high fiber			0		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine neoplasm	Intestine		0	4			References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105
Intestine normal tissue (control)	Intestine					not applicable	References: Mikaelian I, Personal Communication 2002;(): 6 pathology image(s)
Intestine polyp	Intestine			0		observed	References: Maywald RL, Proc Natl Acad Sci U S A 2015 May 12;112(19):E2487-96 ⋅ Podsypanina K, Proc Natl Acad Sci U S A 1999 Feb 16;96(4):1563-8
Intestine tumor	Intestine					0 - observed	References: Kucherlapati MH, PLoS One 2013;8(7):e68817 ⋅ Maywald RL, Proc Natl Acad Sci U S A 2015 May 12;112(19):E2487-96
Intestine tumor	Intestine	BEZ235 (NVP-BEZ235-AN)				0	References: Kucherlapati MH, PLoS One 2013;8(7):e68817
Intestine tumor	Intestine	(see notes regarding diet)			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine tumor	Intestine	AIN-76A			0 - 26.67		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine tumor	Intestine	New western diet (NWD) TD.96096			0 - 53.33		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine tumor	Intestine	New western diet (NWD) TD.96096 ⋅ vitamin D₃ (1alpha,25-(OH)₂-D₃) (VD₃) ⋅ Calcium-enriched			5.56 - 15.38		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine tumor	Intestine	New western diet (NWD) TD.96096 ⋅ Folic acid-enriched			7.14 - 44.44		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine tumor	Intestine	choline-enriched ⋅ New western diet (NWD) TD.96096			13.04 - 33.33		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine tumor	Intestine	methionine-enriched ⋅ New western diet (NWD) TD.96096			22.22 - 37.5		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Intestine tumor	Intestine	New western diet (NWD) TD.96096 ⋅ high fiber			5.88 - 35.29		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Kidney - Cortex cyst	Kidney - Cortex		7.7				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Kidney - Cortex cyst	Kidney - Cortex	calorie restricted	0				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Kidney - Renal tubule cyst	Kidney - Renal tubule			observed			References: Sundberg J, MGI Direct Data Submission 2007;():
Kidney adenoma	Kidney		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Kidney cyst	Kidney		observed	observed			References: Sundberg J, MGI Direct Data Submission 2007;():
Kidney cyst - macrocyst	Kidney		2	4			References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10
Kidney cyst - microcyst	Kidney		4	4			References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10
Kidney lesion	Kidney		10	2.0			References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Kidney lesion	Kidney	calorie restricted	0 - 2.0	2.0 - 4.0			References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Kidney metaplasia - osseous	Kidney		0	2			References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10
Kidney normal tissue (control)	Kidney					not applicable	References: Mikaelian I, Personal Communication 2002;(): ⋅ Mikaelian I, Personal Communication 2004;(): 7 pathology image(s)
Kidney transitional cell hyperplasia	Kidney		2	0			References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10
Kidney tumor - round cell	Kidney		0				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Kidney tumor - round cell	Kidney	calorie restricted	0				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell tumor	Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Leukocyte - Lymphocyte - B-lymphocyte tumor	Leukocyte - Lymphocyte - B-lymphocyte	jet-lag light cycle				observed	References: Kettner NM, Cancer Cell 2016 Dec 12;30(6):909-924
Leukocyte - Lymphocyte - T-lymphocyte lymphoma	Thymus	gamma-radiation			observed	100	References: Bueno MJ, Cancer Cell 2008 Jun;13(6):496-506 ⋅ Garcia-Fernandez RA, Lab Invest 2011 Nov;91(11):1634-42
Leukocyte - Lymphocyte - T-lymphocyte normal tissue (control)	Thymus	gamma-radiation			not applicable		References: Bueno MJ, Cancer Cell 2008 Jun;13(6):496-506
Leukocyte - Lymphocyte leukemia - lymphocytic	Leukocyte - Lymphocyte		0 - 2	1		6	References: Hoag WG, Ann N Y Acad Sci 1963 Nov 4;108():805-831 ⋅ Staats J, Companion to Mouse News Lett No. 21 1959;():
Leukocyte - Lymphocyte leukemia - lymphocytic	Lung		7.7				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Leukocyte - Lymphocyte leukemia - lymphocytic	Spleen		0				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Leukocyte - Lymphocyte leukemia - lymphocytic	Liver		7.7				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Leukocyte - Lymphocyte leukemia - lymphocytic	Lung	calorie restricted	0				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Leukocyte - Lymphocyte leukemia - lymphocytic	Spleen	calorie restricted	6.7				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Leukocyte - Lymphocyte leukemia - lymphocytic	Liver	calorie restricted	0				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Leukocyte - Lymphocyte lymphoma	Leukocyte - Lymphocyte	N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)			50		References: Fenske TS, Cancer Res 2006 May 15;66(10):5029-38
Leukocyte - Lymphocyte normal tissue (control)	Lymph node					not applicable	References: Mikaelian I, Personal Communication 2004;(): 7 pathology image(s)
Leukocyte - Lymphocyte normal tissue (control)	Spleen - White pulp					not applicable	References: Mikaelian I, Personal Communication 2004;(): 1 pathology image(s)
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Leukocyte - Monocyte - Macrophage - Histiocyte		0 - 9	0 - 51	observed	observed	References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 ⋅ Nakamura K, Jikken Dobutsu 1992 Jul;41(3):279-85 ⋅ Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Lung		0				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Abdominal cavity		7.7				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Spleen		0 - 15	0			References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8 ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Liver		0 - 6	12			References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10 ⋅ McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Lymph node		0				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Lung	calorie restricted	0				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Abdominal cavity	calorie restricted	0				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Spleen	calorie restricted	10				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Liver	calorie restricted	23				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Lymph node	calorie restricted	0				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Lymph node - Mesenteric		observed				References: Sundberg J, MGI Direct Data Submission 2007;():
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma	Uterus		observed				References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1(): 2 pathology image(s)
Leukocyte - Monocyte - Macrophage - Kupffer cell sarcoma	Liver	(see notes regarding diet)			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor	Liver		2	0			References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor	Eye - Eyelid		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor	Lymph node		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor	Skin		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Leukocyte - Myelocyte (Granulocyte) hyperplasia	Bone marrow		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Leukocyte - Myelocyte (Granulocyte) normal tissue (control)	Spleen					not applicable	References: Mikaelian I, Personal Communication 2004;(): 3 pathology image(s)
Leukocyte - Myelocyte (Granulocyte) tumor - malignant	Leukocyte - Myelocyte (Granulocyte)	N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)			0		References: Fenske TS, Cancer Res 2006 May 15;66(10):5029-38
Leukocyte leukemia	Leukocyte		0 - 16	0		2.7	References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80 ⋅ Diwan BA, J Natl Cancer Inst 1973 Dec;51(6):1965-70 ⋅ Myers DD, Life Sci 1970;9(Pt II):1071-80
Leukocyte leukemia	Leukocyte	Friend leukemia virus - "regressing" (RFV)		0			References: Dietz M, Int J Cancer 1972 Jul 15;10(1):99-104
Leukocyte leukemia	Leukocyte	Friend leukemia virus - "conventional" (CFV)		0			References: Dietz M, Int J Cancer 1972 Jul 15;10(1):99-104
Leukocyte leukemia	Leukocyte	1-ethyl-1-nitrosourea (ENU)				20	References: Diwan BA, J Natl Cancer Inst 1973 Dec;51(6):1965-70
Leukocyte leukemia	Leukocyte	cesium-137	0	0			References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80
Leukocyte lymphoma	Leukocyte		0 - 57	0 - 50	observed	observed	References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80 ⋅ Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 ⋅ Fong LY, Cancer Res 2003 Jan 1;63(1):186-95 ⋅ Nakamura K, Jikken Dobutsu 1992 Jul;41(3):279-85 ⋅ Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Leukocyte lymphoma	Leukocyte	zinc-deficient		0			References: Fong LY, Cancer Res 2003 Jan 1;63(1):186-95
Leukocyte lymphoma	Kidney		0 - 14	6.0			References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8 ⋅ Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Leukocyte lymphoma	Lung		0 - 20	8.0			References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8 ⋅ Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Leukocyte lymphoma	Thymus		0				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Leukocyte lymphoma	Spleen		0 - 12	2.0			References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8 ⋅ Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Leukocyte lymphoma	Liver		6 - 8.0	6.0 - 8			References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10 ⋅ McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8 ⋅ Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Leukocyte lymphoma	Pancreas		0				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Leukocyte lymphoma	Lymph node		15				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Leukocyte lymphoma	Kidney	calorie restricted	0 - 6.7	0 - 2.0			References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8 ⋅ Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Leukocyte lymphoma	Lung	calorie restricted	0	2.0			References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8 ⋅ Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Leukocyte lymphoma	Thymus	calorie restricted	3.3				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Leukocyte lymphoma	Spleen	calorie restricted	0 - 6.7	0			References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8 ⋅ Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Leukocyte lymphoma	Liver	calorie restricted	0 - 10	2.0 - 8.0			References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8 ⋅ Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Leukocyte lymphoma	Pancreas	calorie restricted	0				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Leukocyte lymphoma	Lymph node	calorie restricted	10				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Leukocyte lymphoma	Leukocyte	cesium-137	5.3	21			References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80
Leukocyte lymphoma	Heart		0	0			References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Leukocyte lymphoma	Heart	calorie restricted	0	0			References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Leukocyte lymphoma - lymphosarcoma	Leukocyte		0	0			References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80
Leukocyte lymphoma - lymphosarcoma	Leukocyte	cesium-137	5.3	0			References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80
Leukocyte lymphoma - non-Hodgkin	Leukocyte	(see notes regarding diet)			observed - 3.93		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Leukocyte lymphoma - non-Hodgkin	Leukocyte	AIN-76A			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Leukocyte neoplasia	Leukocyte				67		References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():
Liver - Bile duct adenoma	Liver - Bile duct		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Liver - Bile duct cyst - macrocyst	Liver - Bile duct		0	0			References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10
Liver - Bile duct hyperplasia	Liver - Bile duct		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Liver - Hepatocyte foci - basophilic	Liver - Hepatocyte	N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)		observed			References: Wastl UM, Mol Carcinog 1998 Aug;22(4):229-34
Liver - Hepatocyte foci - basophilic	Liver - Hepatocyte	phenobarbital (PB) ⋅ N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)		observed			References: Wastl UM, Mol Carcinog 1998 Aug;22(4):229-34
Liver - Hepatocyte foci - eosinophilic	Liver - Hepatocyte	phenobarbital (PB) ⋅ N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)		observed			References: Wastl UM, Mol Carcinog 1998 Aug;22(4):229-34
Liver adenoma	Liver				1		References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():
Liver adenoma	Liver	tricaprylin (trioctanoin)		0			References: Drinkwater NR, Carcinogenesis 1986 Oct;7(10):1701-7
Liver adenoma	Liver	tricaprylin (trioctanoin) ⋅ diethylnitrosamine (DEN)		observed			References: Drinkwater NR, Carcinogenesis 1986 Oct;7(10):1701-7
Liver carcinoma	Liver		0	2.0			References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Liver carcinoma	Liver	calorie restricted	0	0			References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Liver cyst	Liver		0	0	3		References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112 ⋅ Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():
Liver cyst	Liver	calorie restricted	0	0			References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Liver cyst - macrocyst	Liver		2	0			References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10
Liver cystadenoma	Liver		0	0			References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80
Liver cystadenoma	Liver	cesium-137	0	14			References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80
Liver foci - clear cell	Liver		2	0			References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10
Liver foci - eosinophilic	Liver		2	0			References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10
Liver foci - vacuolated cell	Liver		0	0			References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10
Liver hepatoblastoma	Liver			observed			References: Sundberg J, MGI Direct Data Submission 2007;(): 5 pathology image(s)
Liver hepatoblastoma	Liver	(see notes regarding diet)			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Liver hepatocellular adenoma	Liver	phenobarbital (PB) ⋅ N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)		observed			References: Wastl UM, Mol Carcinog 1998 Aug;22(4):229-34
Liver hepatocellular adenoma	Liver		2	0			References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10
Liver hepatocellular carcinoma	Liver		0	0 - 8.8		0	References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10 ⋅ Kettner NM, Cancer Cell 2016 Dec 12;30(6):909-924 ⋅ Nakamura K, Jikken Dobutsu 1992 Jul;41(3):279-85 ⋅ Sundberg J, MGI Direct Data Submission 2007;():
Liver hepatocellular carcinoma	Liver	N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)		observed			References: Wastl UM, Mol Carcinog 1998 Aug;22(4):229-34
Liver hepatocellular carcinoma	Liver	phenobarbital (PB) ⋅ N-diethylnitrosamine (N,N-diethylnitrosamine) (N-nitrosodiethylamine) (NDEA) (diethylnitrosamine) (DEN)		observed			References: Wastl UM, Mol Carcinog 1998 Aug;22(4):229-34
Liver hepatocellular carcinoma	Liver	aflatoxin B1 (AFB₁) (AFB1)		26.67			References: McGlynn KA, Cancer Res 2003 Aug 1;63(15):4594-601
Liver hepatocellular carcinoma	Liver	tricaprylin (trioctanoin)		0			References: Drinkwater NR, Carcinogenesis 1986 Oct;7(10):1701-7 ⋅ McGlynn KA, Cancer Res 2003 Aug 1;63(15):4594-601
Liver hepatocellular carcinoma	Liver	jet-lag light cycle	observed	observed		8.75	References: Kettner NM, Cancer Cell 2016 Dec 12;30(6):909-924
Liver hepatocellular carcinoma	Liver	high saturated fat, high sucrose		observed			References: Tschida BR, Cancer Res 2017 Dec 1;77(23):6576-6588
Liver hepatocellular carcinoma	Liver	tricaprylin (trioctanoin) ⋅ diethylnitrosamine (DEN)		observed			References: Drinkwater NR, Carcinogenesis 1986 Oct;7(10):1701-7
Liver hepatoma	Liver		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Liver hyperplasia	Liver				3	15.45	References: Kettner NM, Cancer Cell 2016 Dec 12;30(6):909-924 ⋅ Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():
Liver hyperplasia	Liver	jet-lag light cycle				75	References: Kettner NM, Cancer Cell 2016 Dec 12;30(6):909-924
Liver lesion	Liver		0	12			References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Liver lesion	Liver	calorie restricted	0 - 8.0	4.0 - 26			References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Liver lesion	Liver	Propylene glycol ⋅ 4-nitroquinoline-1-oxide (4NQO)	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Liver lesion	Liver	Propylene glycol	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Liver neoplasm	Liver		0	0 - 4			References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105
Liver normal tissue (control)	Liver					not applicable	References: Mikaelian I, Personal Communication 2002;(): ⋅ Mikaelian I, Personal Communication 2004;(): 12 pathology image(s)
Liver preneoplastic lesion	Liver	tricaprylin (trioctanoin)		0			References: Drinkwater NR, Carcinogenesis 1986 Oct;7(10):1701-7
Liver preneoplastic lesion	Liver	tricaprylin (trioctanoin) ⋅ diethylnitrosamine (DEN)		observed			References: Drinkwater NR, Carcinogenesis 1986 Oct;7(10):1701-7
Liver tumor	Liver	7,12-dimethylbenz[a]anthracene (DMBA)		observed			References: Kalkuhl A, Hepatology 1998 Apr;27(4):1081-8
Liver tumor	Liver					0 - low	References: Davis LM, Carcinogenesis 1994 Aug;15(8):1637-45 ⋅ Schneider JL, Aging Cell 2015 Apr;14(2):249-64 ⋅ Takagi H, Cancer Res 1992 Oct 1;52(19):5171-7
Liver tumor	Liver	(see notes regarding diet)			observed - 2.81		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Liver tumor	Liver	AIN-76A			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Liver tumor	Liver	methionine-enriched ⋅ New western diet (NWD) TD.96096			0		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Liver tumor	Liver	Propylene glycol ⋅ 4-nitroquinoline-1-oxide (4NQO)	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Liver tumor	Liver	Propylene glycol	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Liver tumor	Liver	tricaprylin (trioctanoin)		0			References: Drinkwater NR, Carcinogenesis 1986 Oct;7(10):1701-7
Liver tumor	Liver	tricaprylin (trioctanoin) ⋅ diethylnitrosamine (DEN)		29.73 - 76.19			References: Drinkwater NR, Carcinogenesis 1986 Oct;7(10):1701-7
Liver tumor	Liver	tricaprylin (trioctanoin) ⋅ 1-ethyl-1-nitrosourea (ENU)		26.92			References: Drinkwater NR, Carcinogenesis 1986 Oct;7(10):1701-7
Liver tumor	Liver	1-ethyl-1-nitrosourea (ENU)	observed	observed	0		References: Kemp CJ, Cancer Res 1989 Sep 15;49(18):5044-7
Liver tumor	Lung	1-ethyl-1-nitrosourea (ENU)	observed				References: Kemp CJ, Cancer Res 1989 Sep 15;49(18):5044-7
Lung - Alveolus adenoma	Lung - Alveolus	(see notes regarding diet)			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Lung - Alveolus carcinoma	Lung - Alveolus	(see notes regarding diet)			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Lung - Bronchiole adenoma	Lung - Bronchiole	(see notes regarding diet)			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Lung - Bronchiole carcinoma	Lung - Bronchiole	(see notes regarding diet)			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Lung adenocarcinoma	Lung				3		References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():
Lung adenoma	Lung	urethane (ethyl carbamate)			57 - 100	observed - 48	References: Malkinson AM, J Natl Cancer Inst 1983 May;70(5):931-6 ⋅ Malkinson AM, J Natl Cancer Inst 1985 Nov;75(5):971-4 ⋅ Thaete LG, Cancer Lett 1991 Dec 9;61(1):15-20
Lung adenoma	Lung	1-ethyl-1-nitrosourea (ENU)				7.1	References: Diwan BA, J Natl Cancer Inst 1973 Dec;51(6):1965-70
Lung adenoma	Lung		0	observed - very low	1	0	References: Berndt A, Cancer Res 2011 Sep 1;71(17):5779-91 ⋅ Diwan BA, J Natl Cancer Inst 1973 Dec;51(6):1965-70 ⋅ Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112 ⋅ Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1(): ⋅ Sundberg J, MGI Direct Data Submission 2007;(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1(): 9 pathology image(s)
Lung adenoma	Lung	urethane (ethyl carbamate) ⋅ butylated hydroxytoluene (BHT)			54		References: Malkinson AM, J Natl Cancer Inst 1983 May;70(5):931-6
Lung adenoma	Lung	calorie restricted	0	0			References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Lung adenoma	Lung	tricaprylin (trioctanoin) ⋅ 1-ethyl-1-nitrosourea (ENU)		observed			References: Drinkwater NR, Carcinogenesis 1986 Oct;7(10):1701-7
Lung carcinoma	Lung			11			References: Nakamura K, Jikken Dobutsu 1992 Jul;41(3):279-85
Lung carcinoma	Lung	N-ethyl-N-nitrosourea (N-nitrosoethylurea) (ENU)			0		References: Fenske TS, Cancer Res 2006 May 15;66(10):5029-38
Lung hyperplasia	Lung		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Lung lesion	Lung	Propylene glycol ⋅ 4-nitroquinoline-1-oxide (4NQO)	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Lung lesion	Lung	Propylene glycol	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Lung neoplasm	Lung		2	8			References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105
Lung normal tissue (control)	Lung					not applicable	References: Mikaelian I, Personal Communication 2003;(): ⋅ Mikaelian I, Personal Communication 2004;(): 8 pathology image(s)
Lung tumor	Lung		0 - 3	0 - 1		1	References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8 ⋅ Hoag WG, Ann N Y Acad Sci 1963 Nov 4;108():805-831 ⋅ Ryan J, J Natl Cancer Inst 1987 Dec;79(6):1351-7
Lung tumor	Lung	uranium ore dust		0			References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8
Lung tumor	Lung	radon		0			References: Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8
Lung tumor	Lung	urethane (ethyl carbamate)		60 - 100	observed - 100	57	References: Chen B, Proc Natl Acad Sci U S A 1994 Feb 15;91(4):1589-93 ⋅ Dwyer-Nield LD, Int J Cancer 2010 Jan 1;126(1):125-32 ⋅ Groch KM, Int J Radiat Biol 1997 Mar;71(3):301-8
Lung tumor	Lung	urethane (ethyl carbamate) ⋅ butylated hydroxytoluene (BHT)		100			References: Dwyer-Nield LD, Int J Cancer 2010 Jan 1;126(1):125-32
Lung tumor	Lung	(see notes regarding diet)			observed - 4.21		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Lung tumor	Lung	AIN-76A			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Lung tumor	Lung	Propylene glycol ⋅ 4-nitroquinoline-1-oxide (4NQO)	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Lung tumor	Lung	Propylene glycol	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Lung tumor	Lung	1-ethyl-1-nitrosourea (ENU)		observed	observed		References: Kemp CJ, Cancer Res 1989 Sep 15;49(18):5044-7
Lung tumor - malignant	Lung		2.0	4.0			References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Lung tumor - malignant	Lung	calorie restricted	0	2.0			References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Lymph node cyst	Lymph node		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Lymph node hyperplasia	Reticulocyte		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Lymph node normal tissue (control)	Lymph node					not applicable	References: Mikaelian I, Personal Communication 2003;(): 1 pathology image(s)
Mammary gland adenocarcinoma	Mammary gland		0 - 1	0			References: Hoag WG, Ann N Y Acad Sci 1963 Nov 4;108():805-831
Mammary gland adenocarcinoma - intraductal	Mammary gland		observed				References: Mikaelian I, Personal Communication 2004;(): 1 pathology image(s)
Mammary gland neoplasm	Mammary gland		0	0			References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105
Mammary gland normal tissue (control)	Mammary gland		not applicable			not applicable	References: Mikaelian I, Personal Communication 2003;(): ⋅ Mikaelian I, Personal Communication 2004;(): 14 pathology image(s)
Mammary gland tumor	Mammary gland		1			0 - 1	References: Bradlow HL, Proc Natl Acad Sci U S A 1985 Sep;82(18):6295-9 ⋅ Felicio LS, Exp Gerontol 1980;15(2):139-43 ⋅ Staats J, Companion to Mouse News Lett No. 29 1963;():
Mesodermal cell/mesoblast myxosarcoma	Muscle - Striated - Skeletal		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Mesodermal cell/mesoblast sarcoma	Intestine - Small Intestine - Brunner's gland			observed			References: Sundberg J, MGI Direct Data Submission 2007;(): 5 pathology image(s)
Mesodermal cell/mesoblast sarcoma	Liver			observed			References: Sundberg J, MGI Direct Data Submission 2007;():
Mesodermal cell/mesoblast sarcoma	Peritoneal cavity		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Mesodermal cell/mesoblast sarcoma	Seminal vesicle			0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Mesodermal cell/mesoblast sarcoma	Stomach - Glandular		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Mesodermal cell/mesoblast sarcoma	Urinary bladder		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Mesodermal cell/mesoblast sarcoma - round cell	Lung		0				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Mesodermal cell/mesoblast sarcoma - round cell	Liver		7.7				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Mesodermal cell/mesoblast sarcoma - round cell	Lymph node		7.7				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Mesodermal cell/mesoblast sarcoma - round cell	Lung	calorie restricted	3.3				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Mesodermal cell/mesoblast sarcoma - round cell	Liver	calorie restricted	6.7				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Mesodermal cell/mesoblast sarcoma - round cell	Lymph node	calorie restricted	6.7				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Mesodermal cell/mesoblast sarcoma - stromal	Uterus - Endometrium - Stroma		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Mesothelium foci	Mesothelium	crocidolite asbestos				18.18	References: Robinson C, Cancer Res 2006 Nov 15;66(22):10786-94
Mesothelium mesothelioma	Mesothelium	crocidolite asbestos				86.67 - 100	References: Robinson C, Cancer Res 2006 Nov 15;66(22):10786-94
Mesothelium mesothelioma	Mesothelium					0	References: Robinson C, Cancer Res 2006 Nov 15;66(22):10786-94
Mesothelium mesothelioma - malignant - sarcomatoid	Mesothelium	crocidolite asbestos				18.18	References: Robinson C, Cancer Res 2006 Nov 15;66(22):10786-94
Mesothelium tumor - benign	Mesothelium	crocidolite asbestos				45.45	References: Robinson C, Cancer Res 2006 Nov 15;66(22):10786-94
Mouth - Oral mucosa cyst	Mouth - Oral mucosa		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Muscle - Smooth leiomyoma	Vagina		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Muscle - Smooth leiomyosarcoma	Intestine - Large Intestine - Cecum		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Muscle - Smooth leiomyosarcoma	Muscle - Smooth		0	0	3		References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Muscle - Smooth leiomyosarcoma	Seminal vesicle			4			References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():
Muscle - Smooth leiomyosarcoma	Intestine - Large Intestine - Colon				1		References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():
Muscle - Smooth leiomyosarcoma	(Unspecified organ)	(see notes regarding diet)			observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Muscle - Striated - Skeletal normal tissue (control)	Muscle - Striated - Skeletal		not applicable			not applicable	References: Mikaelian I, Personal Communication 2004;(): 3 pathology image(s)
Muscle - Striated - Skeletal rhabdomyosarcoma	Muscle - Striated - Skeletal		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Muscle - Striated - Skeletal rhabdomyosarcoma - pleomorphic	Muscle - Striated - Skeletal				0		References: Sher RB, PLoS One 2011;6(8):e23498
Myoepithelial cell myoepithelioma	Lung		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Myoepithelial cell myoepithelioma	Mammary gland		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Nail dysplasia	Nail			observed			References: Sundberg J, MGI Direct Data Submission 2007;():
Nail squamous cell carcinoma	Nail		0	0 - observed			References: Sundberg J, MGI Direct Data Submission 2007;(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1(): 4 pathology image(s)
Nerve normal tissue (control)	Nerve					not applicable	References: Mikaelian I, Personal Communication 2003;(): ⋅ Mikaelian I, Personal Communication 2004;(): 3 pathology image(s)
Oral cavity normal tissue (control)	Oral cavity					not applicable	References: Mikaelian I, Personal Communication 2002;(): ⋅ Mikaelian I, Personal Communication 2004;(): 12 pathology image(s)
Ovary - Follicle cyst - follicular	Ovary - Follicle		low				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Ovary - Granulosa cell tumor	Ovary - Granulosa cell		0 - 2				References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80 ⋅ Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Ovary - Granulosa cell tumor	Ovary - Granulosa cell	cesium-137	5.3				References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80
Ovary - Luteal cell tumor	Ovary - Luteal cell		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Ovary - Sex cord stromal cell adenoma - tubulostromal	Ovary - Sex cord stromal cell		observed				References: Sundberg J, MGI Direct Data Submission 2007;(): 3 pathology image(s)
Ovary adenoma	Ovary		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Ovary cyst	Ovary		4				References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():
Ovary cyst - bursal	Ovary		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Ovary cystadenoma	Ovary		0				References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80
Ovary cystadenoma	Ovary	cesium-137	42				References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80
Ovary hyperplasia - epithelial	Ovary		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Ovary luteoma	Ovary		observed				References: Sundberg J, MGI Direct Data Submission 2007;():
Ovary neoplasm	Ovary		1				References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105
Ovary tumor	Ovary		0				References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80
Ovary tumor	Ovary	cesium-137	47				References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80
Ovary tumor	Ovary	jet-lag light cycle				observed	References: Kettner NM, Cancer Cell 2016 Dec 12;30(6):909-924
Ovary tumor - tubulostromal	Ovary		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Oviduct hyperplasia	Oviduct		observed				References: Mikaelian I, Personal Communication 2004;(): 3 pathology image(s)
Oviduct normal tissue (control)	Oviduct		not applicable				References: Mikaelian I, Personal Communication 2004;(): 6 pathology image(s)
PNS - Nerve sheath tumor	Ear		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
PNS - Nerve sheath tumor	Skin		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Pancreas - Duct adenoma	Pancreas - Duct		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Pancreas - Islet of Langerhans - Beta cell tumor	Pancreas - Islet of Langerhans - Beta cell					0	References: Christofori G, Nature 1994 Jun 2;369(6479):414-8
Pancreas - Islet of Langerhans hyperplasia	Pancreas - Islet of Langerhans		observed	observed			References: Sundberg J, MGI Direct Data Submission 2007;():
Pancreas neoplasm	Pancreas		0	0			References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105
Pancreas normal tissue (control)	Pancreas					not applicable	References: Mikaelian I, Personal Communication 2002;(): ⋅ Mikaelian I, Personal Communication 2004;(): 5 pathology image(s)
Pancreas tumor	Pancreas	jet-lag light cycle				observed	References: Kettner NM, Cancer Cell 2016 Dec 12;30(6):909-924
Peritoneum - Mesentery hyperplasia	Peritoneum - Mesentery					observed	References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1(): 1 pathology image(s)
Peyer's patch normal tissue (control)	Peyer's patch					not applicable	References: Mikaelian I, Personal Communication 2004;(): 5 pathology image(s)
Pituitary gland - Pars distalis adenocarcinoma	Pituitary gland - Pars distalis				1		References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1(): 2 pathology image(s)
Pituitary gland - Pars distalis adenoma	Pituitary gland - Pars distalis		20 - 31	0			References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10 ⋅ McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Pituitary gland - Pars distalis adenoma	Pituitary gland - Pars distalis	calorie restricted	3.3				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Pituitary gland - Pars distalis cyst - microcyst	Pituitary gland - Pars distalis		2	0			References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10
Pituitary gland - Pars distalis hyperplasia - focal	Pituitary gland - Pars distalis		12	0			References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10
Pituitary gland - Pars distalis tumor	Pituitary gland - Pars distalis		0 - 83				References: Schechter JE, Anat Rec 1981 Mar;199(3):423-32
Pituitary gland - Pars intermedia adenoma	Pituitary gland - Pars intermedia		0 - observed	0			References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10 ⋅ Sundberg J, MGI Direct Data Submission 2007;():
Pituitary gland - Pars intermedia hyperplasia	Pituitary gland - Pars intermedia		4	0			References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10
Pituitary gland adenoma	Pituitary gland			0	6		References: Nakamura K, Jikken Dobutsu 1992 Jul;41(3):279-85 ⋅ Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():
Pituitary gland carcinoma	Pituitary gland		2	0			References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10
Pituitary gland cyst - microcyst	Pituitary gland		2	2			References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10
Pituitary gland hyperplasia	Pituitary gland		observed				References: Felicio LS, Exp Gerontol 1980;15(2):139-43
Pituitary gland hyperplasia - focal	Pituitary gland		0	0			References: Igarashi I, J Vet Med Sci 2013 Feb;75(2):207-10
Pituitary gland neoplasm	Pituitary gland		4 - 7	0			References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105
Pituitary gland tumor	Pituitary gland		0 - 61	sporadic		observed	References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105 ⋅ Felicio LS, Exp Gerontol 1980;15(2):139-43
Pituitary gland tumor	Pituitary gland	ovariectomy	very low				References: Felicio LS, Exp Gerontol 1980;15(2):139-43
Placenta normal tissue (control)	Placenta		not applicable				References: Mikaelian I, Personal Communication 2003;(): ⋅ Mikaelian I, Personal Communication 2004;(): 4 pathology image(s)
Preputial/Clitoral gland (sex not specified) normal tissue (control)	Preputial/Clitoral gland (sex not specified)					not applicable	References: Mikaelian I, Personal Communication 2002;(): ⋅ Mikaelian I, Personal Communication 2003;(): ⋅ Mikaelian I, Personal Communication 2004;(): 5 pathology image(s)
Prostate gland - Anterior lobe adenocarcinoma	Prostate gland - Anterior lobe			0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Prostate gland normal tissue (control)	Prostate gland			not applicable			References: Mikaelian I, Personal Communication 2004;(): 2 pathology image(s)
Prostate gland prostatic intraepithelial neoplasia (PIN)	Prostate gland			observed			References: Pathbase web site, University of Cambridge, MGI Direct Data Submission 2009;(): 8 pathology image(s)
Salivary gland - Parotid hyperplasia	Salivary gland - Parotid			observed			References: Sundberg J, MGI Direct Data Submission 2007;():
Salivary gland normal tissue (control)	Salivary gland		not applicable			not applicable	References: Mikaelian I, Personal Communication 2003;(): ⋅ Mikaelian I, Personal Communication 2004;(): 9 pathology image(s)
Seminal vesicle normal tissue (control)	Seminal vesicle			not applicable			References: Mikaelian I, Personal Communication 2004;(): 3 pathology image(s)
Skin - Dorsal region adenoma - sebaceous	Skin - Dorsal region		observed				References: Sundberg J, Personal Communication 1997;(): 4 pathology image(s)
Skin - Dorsal region papilloma	Skin - Dorsal region		observed				References: Sundberg J, Personal Communication 1997;():
Skin - Dorsal region tumor	Skin - Dorsal region	mouse papillomavirus (MmuPV1)	0				References: Sundberg JP, PLoS One 2014;9(12):e113582
Skin - Epidermis - Basal cell carcinoma	Skin - Epidermis - Basal cell		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Skin - Epidermis cyst - inclusion	Skin - Epidermis		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Skin - Epidermis hamartoma	Skin - Epidermis		observed				References: Mikaelian I, Personal Communication 2002;(): 1 pathology image(s)
Skin - Epidermis hyperplasia	Skin - Epidermis		observed				References: Sundberg J, Personal Communication 1997;():
Skin - Facial region tumor	Skin - Facial region	mouse papillomavirus (MmuPV1)	0				References: Sundberg JP, PLoS One 2014;9(12):e113582
Skin - Hair follicle hyperplasia	Skin - Hair follicle		observed				References: Sundberg J, Personal Communication 1997;():
Skin - Tail tumor	Skin - Tail	mouse papillomavirus (MmuPV1)	0				References: Sundberg JP, PLoS One 2014;9(12):e113582
Skin - Vibrissa squamous cell carcinoma in situ	Skin - Vibrissa		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Skin gland - Sweat gland hyperplasia	Ear - Outer ear - Ear canal		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Skin hyperplasia	Skin		observed				References: Sundberg J, Personal Communication 1997;(): 8 pathology image(s)
Skin hyperplasia - epithelial	Ear		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Skin hyperplasia - epithelial	Eye - Eyelid		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Skin lesion	Skin	12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ 7,12-dimethylbenz[a]anthracene (DMBA)				observed	References: Sotillo R, Proc Natl Acad Sci U S A 2001 Nov 6;98(23):13312-7
Skin lesion	Skin	mouse papillomavirus (MmuPV1)	0				References: Sundberg JP, PLoS One 2014;9(12):e113582 6 pathology image(s)
Skin normal tissue (control)	Skin					not applicable	References: Mikaelian I, Personal Communication 2002;(): ⋅ Mikaelian I, Personal Communication 2003;(): ⋅ Mikaelian I, Personal Communication 2004;(): 64 pathology image(s)
Skin papilloma	Skin	12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ 7,12-dimethylbenz[a]anthracene (DMBA)				very high	References: Sotillo R, Proc Natl Acad Sci U S A 2001 Nov 6;98(23):13312-7
Skin squamous cell carcinoma	Skin			observed	1		References: Pathbase web site, University of Cambridge, MGI Direct Data Submission 2009;(): ⋅ Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1(): 1 pathology image(s)
Skin tumor	Skin	12-O-tetradecanoylphorbol-13-acetate (TPA) ⋅ 7,12-dimethylbenz[a]anthracene (DMBA)				42	References: Sundberg JP, Mol Carcinog 1997 SEP;20(1):19-32
Skin tumor	Skin			0		11	References: Nakamura K, Jikken Dobutsu 1992 Jul;41(3):279-85 ⋅ Staats J, Companion to Mouse News Lett No. 21 1959;():
Spleen normal tissue (control)	Spleen					not applicable	References: Mikaelian I, Personal Communication 2004;(): 21 pathology image(s)
Spleen tumor	Spleen		0	6.0			References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Spleen tumor	Spleen	calorie restricted	0 - 4.0	2.0 - 10			References: Mitchell SJ, Cell Metab 2016 Jun 14;23(6):1093-1112
Spleen tumor - round cell	Spleen		0				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Spleen tumor - round cell	Spleen	calorie restricted	0				References: McDonald RB, Exp Gerontol 2008 Dec;43(12):1061-8
Stomach - Epithelium hyperplasia - squamous	Stomach - Epithelium		observed				References: Sundberg J, MGI Direct Data Submission 2007;():
Stomach - Glandular adenoma	Stomach - Glandular		0	low			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Stomach - Glandular cyst	Stomach - Glandular		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Stomach - Glandular cyst - glandular	Stomach - Glandular		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Stomach - Glandular hyperplasia	Stomach - Glandular		low	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Stomach - Glandular hyperplasia - adenomatous	Stomach - Glandular		low	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Stomach - Glandular normal tissue (control)	Stomach - Glandular					not applicable	References: Mikaelian I, Personal Communication 2004;(): 1 pathology image(s)
Stomach - Glandular polyp	Stomach - Glandular		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Stomach adenocarcinoma	Stomach					0	References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54
Stomach adenoma	Stomach					0	References: Yang K, J Exp Zool 1997 Feb 15;277(3):245-54
Stomach adenoma - microadenoma	Stomach	AIN-76A			0		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Stomach adenoma - microadenoma	Stomach	New western diet (NWD) TD.96096			0 - observed		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Stomach adenoma - microadenoma	Stomach	New western diet (NWD) TD.96096 ⋅ vitamin D₃ (1alpha,25-(OH)₂-D₃) (VD₃) ⋅ Calcium-enriched			0		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Stomach adenoma - microadenoma	Salivary gland	New western diet (NWD) TD.96096 ⋅ Folic acid-enriched			0		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Stomach adenoma - microadenoma	Stomach	choline-enriched ⋅ New western diet (NWD) TD.96096			0		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Stomach adenoma - microadenoma	Stomach	methionine-enriched ⋅ New western diet (NWD) TD.96096			0		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Stomach adenoma - microadenoma	Stomach	New western diet (NWD) TD.96096 ⋅ high fiber			0		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
Stomach normal tissue (control)	Stomach					not applicable	References: Mikaelian I, Personal Communication 2002;(): ⋅ Mikaelian I, Personal Communication 2004;(): 2 pathology image(s)
Stomach squamous cell papilloma	Stomach				3		References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():
Testis - Germ cell normal tissue (control)	Testis - Germ cell			not applicable			References: Mikaelian I, Personal Communication 2004;(): 1 pathology image(s)
Testis - Leydig cell (Interstitial cell) adenoma	Testis - Leydig cell (Interstitial cell)			4			References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1():
Testis - Leydig cell (Interstitial cell) cyst	Testis - Leydig cell (Interstitial cell)			0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Testis - Leydig cell (Interstitial cell) hyperplasia	Testis - Leydig cell (Interstitial cell)			0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Testis - Leydig cell (Interstitial cell) normal tissue (control)	Testis - Leydig cell (Interstitial cell)			not applicable			References: Mikaelian I, Personal Communication 2004;(): 1 pathology image(s)
Testis - Leydig cell (Interstitial cell) tumor	Testis - Leydig cell (Interstitial cell)			0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Testis normal tissue (control)	Testis			not applicable			References: Mikaelian I, Personal Communication 2004;(): 1 pathology image(s)
Thymus normal tissue (control)	Thymus					not applicable	References: Mikaelian I, Personal Communication 2003;(): ⋅ Mikaelian I, Personal Communication 2004;(): 35 pathology image(s)
Thyroid gland - Follicular cell cyst	Thyroid gland - Follicular cell		observed	observed			References: Sundberg J, MGI Direct Data Submission 2007;():
Thyroid gland - Follicular cell hyperplasia	Thyroid gland - Follicular cell		observed				References: Mikaelian I, Personal Communication 2004;(): 1 pathology image(s)
Thyroid gland adenoma	Thyroid gland		observed	observed			References: Sundberg J, MGI Direct Data Submission 2007;(): 3 pathology image(s)
Thyroid gland hyperplasia - cystic	Thyroid gland		low	0 - observed			References: Sundberg J, MGI Direct Data Submission 2007;(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Thyroid gland neoplasm	Thyroid gland		0	0			References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105
Tongue atypia	Tongue	Propylene glycol ⋅ 4-nitroquinoline-1-oxide (4NQO)	observed				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Tongue carcinoma in situ	Tongue	Propylene glycol ⋅ 4-nitroquinoline-1-oxide (4NQO)	observed				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Tongue dysplasia	Tongue	Propylene glycol ⋅ 4-nitroquinoline-1-oxide (4NQO)	observed				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Tongue dysplasia - high grade	Tongue	Propylene glycol ⋅ 4-nitroquinoline-1-oxide (4NQO)	observed				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Tongue hyperplasia	Tongue	Propylene glycol ⋅ 4-nitroquinoline-1-oxide (4NQO)	observed				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Tongue lesion	Tongue	Propylene glycol	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Tongue lesion	Tongue	Propylene glycol ⋅ 4-nitroquinoline-1-oxide (4NQO)	0 - 100				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Tongue normal tissue (control)	Tongue		not applicable			not applicable	References: Mikaelian I, Personal Communication 2002;(): ⋅ Mikaelian I, Personal Communication 2004;(): 15 pathology image(s)
Tongue papilloma	Tongue	Propylene glycol	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Tongue papilloma	Tongue	Propylene glycol ⋅ 4-nitroquinoline-1-oxide (4NQO)	100				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Tongue squamous cell carcinoma	Tongue	Propylene glycol	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Tongue squamous cell carcinoma	Tongue	Propylene glycol ⋅ 4-nitroquinoline-1-oxide (4NQO)	observed - 100				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13 Sites of Metastasis: Muscle - Striated - Skeletal
Tongue tumor	Tongue	Propylene glycol	0				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Tongue tumor	Tongue	Propylene glycol ⋅ 4-nitroquinoline-1-oxide (4NQO)	100				References: Tang XH, Clin Cancer Res 2004 Jan 1;10(1 Pt 1):301-13
Tooth dysplasia	Tooth		observed	observed		observed	References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1(): ⋅ Sundberg J, MGI Direct Data Submission 2007;(): 8 pathology image(s)
Trachea normal tissue (control)	Trachea					not applicable	References: Mikaelian I, Personal Communication 2002;(): ⋅ Mikaelian I, Personal Communication 2004;(): 4 pathology image(s)
Ureter - Transitional cell hyperplasia	Ureter - Transitional cell		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Ureter hyperplasia	Ureter		observed				References: Sundberg J, MGI Direct Data Submission 2007;(): 5 pathology image(s)
Ureter hyperplasia	Muscle - Smooth		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Ureter polyp	Ureter		very low	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Urinary bladder - Transitional cell atypia	Urinary bladder - Transitional cell		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Urinary bladder - Transitional cell normal tissue (control)	Urinary bladder - Transitional cell					not applicable	References: Mikaelian I, Personal Communication 2004;(): 3 pathology image(s)
Urinary bladder normal tissue (control)	Urinary bladder					not applicable	References: Mikaelian I, Personal Communication 2003;(): ⋅ Mikaelian I, Personal Communication 2004;(): 6 pathology image(s)
Urinary bladder papilloma	Urinary bladder		0	0			References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Uterus - Endometrium hyperplasia - cystic	Uterus - Endometrium		observed - moderate				References: Pettan-Brewer C, Pathobiol Aging Age Relat Dis 2011;1(): ⋅ Sundberg J, MGI Direct Data Submission 2007;(): ⋅ Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Uterus - Endometrium normal tissue (control)	Uterus - Endometrium		not applicable				References: Mikaelian I, Personal Communication 2004;(): 3 pathology image(s)
Uterus adenoma	Uterus		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Uterus fibropapilloma	Uterus		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Uterus neoplasm	Uterus		4				References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105
Uterus normal tissue (control)	Uterus		not applicable				References: Mikaelian I, Personal Communication 2002;(): ⋅ Mikaelian I, Personal Communication 2004;(): 4 pathology image(s)
Vagina normal tissue (control)	Vagina		not applicable				References: Mikaelian I, Personal Communication 2004;(): 1 pathology image(s)
Vagina papilloma	Vagina		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
Vulva squamous cell carcinoma	Vulva		0				References: Sundberg JP, Pathobiol Aging Age Relat Dis 2011;1():
(Unspecified organ) neoplasm	(Unspecified organ)		35 - 43	38 - 50			References: Brayton CF, Vet Pathol 2012 Jan;49(1):85-105
(Unspecified organ) reticulum cell sarcoma	(Unspecified organ)					9	References: Staats J, Companion to Mouse News Lett No. 21 1959;():
(Unspecified organ) tumor	(Unspecified organ)		0 - 14	0 - 10		0 - low	References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80 ⋅ Kettner NM, Cancer Cell 2016 Dec 12;30(6):909-924 ⋅ Nakamura K, Jikken Dobutsu 1992 Jul;41(3):279-85 ⋅ Staats J, Companion to Mouse News Lett No. 29 1963;(): ⋅ Storer JB, J Gerontol 1966 Jul;21(3):404-9
(Unspecified organ) tumor	(Unspecified organ)	1-ethyl-1-nitrosourea (ENU)				2.4	References: Diwan BA, J Natl Cancer Inst 1973 Dec;51(6):1965-70
(Unspecified organ) tumor	(Unspecified organ)	cesium-137	58	36			References: Antoch MP, Cell Cycle 2013 Dec 1;12(23):3673-80
(Unspecified organ) tumor	(Unspecified organ)	jet-lag light cycle				observed	References: Kettner NM, Cancer Cell 2016 Dec 12;30(6):909-924
(Unspecified organ) tumor	(Unspecified organ)	(see notes regarding diet)			observed - 14.47		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
(Unspecified organ) tumor	(Unspecified organ)	AIN-76A			observed - 6.67		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92
(Unspecified organ) tumor	(Unspecified organ)	New western diet (NWD) TD.96096 ⋅ high fiber			0		References: Newmark HL, Carcinogenesis 2009 Jan;30(1):88-92

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