Mouse Tumor Biology Database (MTB)
MTB Home   Help
Search for Help
 
in these sections
Search Forms
Tumor
Strain
Genetics
Pathology Images
Reference
Advanced
Search MTB Using Human Genes
Gene Expression Data Sets

Additional Resources
new PDX Like Me
PDX Finder
PDX Model Search
Faceted Tumor Search
Dynamic Tumor Frequency Grid
Other Cancer Websites
Immunohistochemistry
Lymphoma Pathology

Mouse Genome Informatics
The Jackson Laboratory
Citing These Resources
Warranty Disclaimer
& Copyright Notice

Send Questions and
Comments to User Support.

Last Database Update
2019-08-18
MTB 3.0
 
HelpHelp and Documentation Strain Tumor Overview
Collapsed View
 
Strain
C57BL/6J
Strain Synonyms B6  •  B/6  •  B6J  •  B6 WT  •  Bl/6  •  Black 6  •  C57  •  C57/B16  •  C57/Bl  •  C57BL  •  C57/Bl6  •  C57BL/6  •  C57BL/6 from Jackson Laboratory  •  C57/Bl 6J  •  C57Bl/6J  •  C57BL6/J  •  C57BL/6J (F129+51)  •  C57BL/6J, H-2b  •  C57BL/6J inbred WT  •  C57BL/6J+/+  •  C57BL/6J (UW)  •  C57BL/6J wild-type  •  C57 Black  •  C57 black subline 6  •  control  •  Ctr  •  p53+/+  •  p53 wild-type (+/+)  •  p21+/+p27+/+  •  wild type  •  wild-type  •  wild-type C57BL/6J  •  wild-type (WT)  •  WT  •  WT-Control  •  WT-CR
Strain Tumor Overview Expanded View
Tumors 429 unique tumor types displayed.

A tumor group is a set of tumors that share the same tumor name, organ(s) affected, and treatment type.

Tumor Name Organ(s) Affected Treatment Type Number of
Tumor Group Records
Frequency Range
Adipose tissue - White lipoma Adipose tissue - White None (spontaneous) 2 0
Adipose tissue lipoma Scrotum None (spontaneous) 1 observed
Adipose tissue lipoma Peritoneal cavity None (spontaneous) 2 0
Adipose tissue lipoma - pedunculated Adipose tissue None (spontaneous) 2 0 - very low
Adrenal gland - Cortex adenoma Adrenal gland - Cortex None (spontaneous) 3 0 - observed
Adrenal gland - Cortex normal tissue (control) Adrenal gland - Cortex None (spontaneous) 1 not applicable
Adrenal gland - Medulla normal tissue (control) Adrenal gland - Medulla None (spontaneous) 3 not applicable
Adrenal gland - Medulla pheochromocytoma Adrenal gland - Medulla None (spontaneous) 2 0
Adrenal gland - Medulla pheochromocytoma - malignant Adrenal gland - Medulla None (spontaneous) 1 1
Adrenal gland - Subcapsular cell hyperplasia Adrenal gland - Subcapsular cell None (spontaneous) 3 0 - observed
Adrenal gland - Subcapsular cell hyperplasia Adrenal gland - Subcapsular cell Diet 4 0 - 2.0
Adrenal gland - Subcapsular cell hyperplasia - spindle cell Adrenal gland - Subcapsular cell None (spontaneous) 2 0 - moderate
Adrenal gland hyperplasia - nodular Adrenal gland None (spontaneous) 2 0
Adrenal gland hyperplasia - spindle cell Adrenal gland None (spontaneous) 4 observed
Adrenal gland tumor - carcinoid Adrenal gland None (spontaneous) 2 0
Blood vessel - Aorta metaplasia - cartilaginous Blood vessel - Aorta None (spontaneous) 1 0
Blood vessel hemangioma Liver None (spontaneous) 2 2 - 6
Blood vessel hemangioma Blood vessel None (spontaneous) 2 0
Blood vessel hemangioma Spleen None (spontaneous) 1 1
Blood vessel hemangioma Uterus None (spontaneous) 1 0
Blood vessel hemangioma - capillary Blood vessel None (spontaneous) 1 observed
Blood vessel hemangioma - capillary Liver None (spontaneous) 1 observed
Blood vessel hemangioma - cavernous Ovary None (spontaneous) 1 observed
Blood vessel hemangioma - cavernous Spleen None (spontaneous) 1 observed
Blood vessel hemangiosarcoma Spleen None (spontaneous) 4 0 - 4.0
Blood vessel hemangiosarcoma Liver None (spontaneous) 9 0 - 2
Blood vessel hemangiosarcoma Spleen Diet 5 0
Blood vessel hemangiosarcoma Liver Diet 5 0
Blood vessel hemangiosarcoma Blood vessel None (spontaneous) 5 0 - 4
Blood vessel hemangiosarcoma Blood vessel Radiation 2 0
Blood vessel hemangiosarcoma Uterus None (spontaneous) 1 observed
Blood vessel hemangiosarcoma Ovary None (spontaneous) 1 observed
Blood vessel hemangiosarcoma Skin None (spontaneous) 1 observed
Blood vessel hemangiosarcoma Muscle - Striated - Skeletal None (spontaneous) 2 0
Blood vessel neoplasm Blood vessel None (spontaneous) 4 2 - 4
Blood vessel normal tissue (control) Blood vessel None (spontaneous) 2 not applicable
Bone - Vertebral column - Vertebra osteosarcoma Bone - Vertebral column - Vertebra None (spontaneous) 1 1
Bone - Vertebral column - Vertebra osteosarcoma - chondroblastic Bone - Vertebral column - Vertebra None (spontaneous) 1 observed
Bone hyperplasia Bone None (spontaneous) 2 0
Bone lesion - fibro-osseous Bone None (spontaneous) 11 0 - 13.33
Bone marrow normal tissue (control) Bone marrow None (spontaneous) 1 not applicable
Bone neoplasm Bone None (spontaneous) 2 0 - 2
Bone osteosarcoma Bone None (spontaneous) 2 observed
CNS - Brain - Choroid plexus normal tissue (control) CNS - Brain - Choroid plexus None (spontaneous) 2 not applicable
CNS - Brain - Ependyma normal tissue (control) CNS - Brain - Ependyma None (spontaneous) 1 not applicable
CNS - Brain - Glial cell normal tissue (control) CNS - Brain - Glial cell None (spontaneous) 1 not applicable
CNS - Brain - Neuron normal tissue (control) CNS - Brain - Neuron None (spontaneous) 1 not applicable
CNS - Brain glioma CNS - Brain None (spontaneous) 1 0
CNS - Brain normal tissue (control) CNS - Brain None (spontaneous) 2 not applicable
CNS - Spinal cord normal tissue (control) CNS - Spinal cord None (spontaneous) 1 not applicable
Connective tissue - Cartilage - Articular hyperplasia Limb - Hindlimb None (spontaneous) 1 0
Connective tissue - Cartilage hyperplasia Bone - Sternum None (spontaneous) 1 0
Connective tissue - Cartilage hyperplasia Ear - Outer ear None (spontaneous) 1 0
Connective tissue - Fibroblast fibrosarcoma Connective tissue - Fibroblast None (spontaneous) 1 4
Connective tissue - Fibroblast fibrosarcoma Uterus None (spontaneous) 1 observed
Connective tissue - Fibroblast fibrosarcoma Skin None (spontaneous) 1 observed
Connective tissue - Fibroblast fibrosarcoma Perirenal tissue None (spontaneous) 1 observed
Connective tissue - Fibroblast fibrosarcoma Ear None (spontaneous) 1 observed
Dendritic cell normal tissue (control) Lymph node None (spontaneous) 1 not applicable
Epididymis cyst Epididymis None (spontaneous) 1 0
Epididymis normal tissue (control) Epididymis None (spontaneous) 1 not applicable
Erythrocyte leukemia - erythroleukemia Spleen None (spontaneous) 3 0
Erythrocyte leukemia - erythroleukemia Liver None (spontaneous) 1 0
Erythrocyte leukemia - erythroleukemia Spleen Diet 1 3.3
Erythrocyte leukemia - erythroleukemia Liver Diet 1 3.3
Erythrocyte neoplasm Erythrocyte None (spontaneous) 2 0
Esophagus hyperplasia Esophagus None (spontaneous) 3 0
Esophagus hyperplasia Esophagus Diet 1 observed
Esophagus normal tissue (control) Esophagus None (spontaneous) 3 not applicable
Esophagus squamous cell carcinoma Esophagus Chemical/Drug 1 observed
Esophagus tumor Esophagus None (spontaneous) 1 0
Esophagus tumor Esophagus Chemical/Drug 2 0 - 100
Esophagus tumor Esophagus Diet 1 0
Eye - Conjunctiva normal tissue (control) Eye - Conjunctiva None (spontaneous) 1 not applicable
Eye - Cornea normal tissue (control) Eye - Cornea None (spontaneous) 3 not applicable
Eye - Eyelid normal tissue (control) Eye - Eyelid None (spontaneous) 1 not applicable
Eye - Harderian gland adenoma Eye - Harderian gland None (spontaneous) 1 observed
Eye - Harderian gland neoplasm Eye - Harderian gland None (spontaneous) 4 0
Eye - Retina normal tissue (control) Eye - Retina None (spontaneous) 1 not applicable
Eye normal tissue (control) Eye None (spontaneous) 1 not applicable
Forestomach - Squamocolumnar junction with the glandular stomach tumor Forestomach - Squamocolumnar junction with the glandular stomach Diet 1 13
Forestomach - Squamocolumnar junction with the glandular stomach tumor Forestomach - Squamocolumnar junction with the glandular stomach Chemical/Drug 1 0
Forestomach hyperplasia Forestomach Diet 1 observed
Forestomach hyperplasia Forestomach None (spontaneous) 1 0
Forestomach hyperplasia - papillary Forestomach None (spontaneous) 2 0
Forestomach normal tissue (control) Forestomach None (spontaneous) 1 not applicable
Forestomach papilloma Forestomach None (spontaneous) 2 very low
Forestomach tumor Forestomach Chemical/Drug 2 0 - 13
Gallbladder cyst Gallbladder None (spontaneous) 2 0
Gallbladder hyperplasia Gallbladder None (spontaneous) 2 0
Gallbladder hyperplasia - papillary Gallbladder None (spontaneous) 2 0
Gastrointestinal tract tumor Gastrointestinal tract None (spontaneous) 1 0
Gingiva squamous cell carcinoma - well differentiated Gingiva None (spontaneous) 1 observed
Heart normal tissue (control) Heart None (spontaneous) 2 not applicable
Intestine - Large Intestine - Cecum hyperplasia Intestine - Large Intestine - Cecum Chemical/Drug 1 observed
Intestine - Large Intestine - Cecum hyperplasia Intestine - Large Intestine - Cecum None (spontaneous) 2 0
Intestine - Large Intestine - Colon - Distal adenocarcinoma Intestine - Large Intestine - Colon - Distal None (spontaneous) 1 0
Intestine - Large Intestine - Colon - Distal adenoma Intestine - Large Intestine - Colon - Distal None (spontaneous) 1 0
Intestine - Large Intestine - Colon - Distal foci - aberrant crypt (ACF) Intestine - Large Intestine - Colon - Distal Chemical/Drug 1 observed
Intestine - Large Intestine - Colon - Distal tumor Intestine - Large Intestine - Colon - Distal Chemical/Drug 1 0
Intestine - Large Intestine - Colon - Medial adenocarcinoma Intestine - Large Intestine - Colon - Medial None (spontaneous) 1 0
Intestine - Large Intestine - Colon - Medial adenoma Intestine - Large Intestine - Colon - Medial None (spontaneous) 1 0
Intestine - Large Intestine - Colon - Proximal adenocarcinoma Intestine - Large Intestine - Colon - Proximal None (spontaneous) 1 0
Intestine - Large Intestine - Colon - Proximal adenoma Intestine - Large Intestine - Colon - Proximal None (spontaneous) 1 0
Intestine - Large Intestine - Colon - Proximal tumor Intestine - Large Intestine - Colon - Proximal Chemical/Drug 1 0
Intestine - Large Intestine - Colon adenoma Intestine - Large Intestine - Colon None (spontaneous) 2 0
Intestine - Large Intestine - Colon hyperplasia Intestine - Large Intestine - Colon Chemical/Drug 2 observed
Intestine - Large Intestine - Colon normal tissue (control) Intestine - Large Intestine - Colon None (spontaneous) 3 not applicable
Intestine - Large Intestine - Colon tumor Intestine - Large Intestine - Colon Chemical/Drug 5 0 - 100
Intestine - Large Intestine adenocarcinoma Intestine - Large Intestine None (spontaneous) 1 0
Intestine - Large Intestine tumor Intestine - Large Intestine Chemical/Drug 1 100
Intestine - Small Intestine - Brunner's gland adenoma Intestine - Small Intestine - Brunner's gland None (spontaneous) 2 0
Intestine - Small Intestine - Brunner's gland hyperplasia Intestine - Small Intestine - Brunner's gland None (spontaneous) 3 0 - observed
Intestine - Small Intestine - Duodenum adenocarcinoma Intestine - Small Intestine - Duodenum None (spontaneous) 1 0
Intestine - Small Intestine - Duodenum adenoma Intestine - Small Intestine - Duodenum None (spontaneous) 3 0
Intestine - Small Intestine - Duodenum cyst Intestine - Small Intestine - Duodenum None (spontaneous) 2 0
Intestine - Small Intestine - Duodenum hyperplasia Intestine - Small Intestine - Duodenum None (spontaneous) 2 0
Intestine - Small Intestine - Duodenum lesion Intestine - Small Intestine - Duodenum Chemical/Drug 2 observed
Intestine - Small Intestine - Duodenum normal tissue (control) Intestine - Small Intestine - Duodenum None (spontaneous) 3 not applicable
Intestine - Small Intestine - Duodenum polyp Intestine - Small Intestine - Duodenum None (spontaneous) 2 0
Intestine - Small Intestine - Ileum adenocarcinoma Intestine - Small Intestine - Ileum None (spontaneous) 1 0
Intestine - Small Intestine - Ileum adenoma Intestine - Small Intestine - Ileum None (spontaneous) 1 0
Intestine - Small Intestine - Ileum normal tissue (control) Intestine - Small Intestine - Ileum None (spontaneous) 1 not applicable
Intestine - Small Intestine - Ileum polyp Intestine - Small Intestine - Ileum None (spontaneous) 2 0
Intestine - Small Intestine - Jejunum adenocarcinoma Intestine - Small Intestine - Jejunum None (spontaneous) 1 0
Intestine - Small Intestine - Jejunum adenoma Intestine - Small Intestine - Jejunum None (spontaneous) 1 0
Intestine - Small Intestine - Jejunum hyperplasia Intestine - Small Intestine - Jejunum None (spontaneous) 2 0
Intestine - Small Intestine - Jejunum polyp Intestine - Small Intestine - Jejunum None (spontaneous) 3 0 - observed
Intestine - Small Intestine normal tissue (control) Intestine - Small Intestine None (spontaneous) 4 not applicable
Intestine - Small Intestine tumor Intestine - Small Intestine None (spontaneous) 1 0
Intestine - Small Intestine tumor Intestine - Small Intestine Chemical/Drug 1 0
Intestine neoplasm Intestine None (spontaneous) 2 0 - 4
Intestine normal tissue (control) Intestine None (spontaneous) 1 not applicable
Intestine polyp Intestine None (spontaneous) 2 0 - observed
Intestine tumor Intestine None (spontaneous) 2 0 - observed
Intestine tumor Intestine Chemical/Drug 1 0
Kidney - Cortex cyst Kidney - Cortex None (spontaneous) 1 7.7
Kidney - Cortex cyst Kidney - Cortex Diet 1 0
Kidney - Renal tubule cyst Kidney - Renal tubule None (spontaneous) 1 observed
Kidney adenoma Kidney None (spontaneous) 2 0
Kidney cyst Kidney None (spontaneous) 2 observed
Kidney cyst - macrocyst Kidney None (spontaneous) 2 2 - 4
Kidney cyst - microcyst Kidney None (spontaneous) 2 4
Kidney lesion Kidney None (spontaneous) 2 2.0 - 10
Kidney lesion Kidney Diet 4 0 - 4.0
Kidney metaplasia - osseous Kidney None (spontaneous) 2 0 - 2
Kidney normal tissue (control) Kidney None (spontaneous) 3 not applicable
Kidney transitional cell hyperplasia Kidney None (spontaneous) 2 0 - 2
Kidney tumor - round cell Kidney None (spontaneous) 1 0
Kidney tumor - round cell Kidney Diet 1 0
Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell tumor Leukocyte - Lymphocyte - B-lymphocyte - Plasma cell None (spontaneous) 2 0
Leukocyte - Lymphocyte - B-lymphocyte tumor Leukocyte - Lymphocyte - B-lymphocyte Other 1 observed
Leukocyte - Lymphocyte - T-lymphocyte lymphoma Thymus Radiation 2 observed - 100
Leukocyte - Lymphocyte - T-lymphocyte normal tissue (control) Thymus Radiation 1 not applicable
Leukocyte - Lymphocyte leukemia - lymphocytic Leukocyte - Lymphocyte None (spontaneous) 4 0 - 6
Leukocyte - Lymphocyte leukemia - lymphocytic Lung None (spontaneous) 1 7.7
Leukocyte - Lymphocyte leukemia - lymphocytic Spleen None (spontaneous) 1 0
Leukocyte - Lymphocyte leukemia - lymphocytic Liver None (spontaneous) 1 7.7
Leukocyte - Lymphocyte leukemia - lymphocytic Lung Diet 1 0
Leukocyte - Lymphocyte leukemia - lymphocytic Spleen Diet 1 6.7
Leukocyte - Lymphocyte leukemia - lymphocytic Liver Diet 1 0
Leukocyte - Lymphocyte lymphoma Leukocyte - Lymphocyte Chemical/Drug 1 50
Leukocyte - Lymphocyte normal tissue (control) Lymph node None (spontaneous) 2 not applicable
Leukocyte - Lymphocyte normal tissue (control) Spleen - White pulp None (spontaneous) 1 not applicable
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Leukocyte - Monocyte - Macrophage - Histiocyte None (spontaneous) 7 0 - 51
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Lung None (spontaneous) 1 0
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Abdominal cavity None (spontaneous) 1 7.7
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Spleen None (spontaneous) 3 0 - 15
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Liver None (spontaneous) 3 0 - 12
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Lymph node None (spontaneous) 1 0
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Lung Diet 1 0
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Abdominal cavity Diet 1 0
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Spleen Diet 1 10
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Liver Diet 1 23
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Lymph node Diet 1 0
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Lymph node - Mesenteric None (spontaneous) 1 observed
Leukocyte - Monocyte - Macrophage - Histiocyte histiocytic sarcoma Uterus None (spontaneous) 1 observed
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Liver None (spontaneous) 2 0 - 2
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Eye - Eyelid None (spontaneous) 2 0
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Lymph node None (spontaneous) 4 0
Leukocyte - Myelocyte (Granulocyte) - Basophil - Mast cell tumor Skin None (spontaneous) 2 0
Leukocyte - Myelocyte (Granulocyte) hyperplasia Bone marrow None (spontaneous) 2 0
Leukocyte - Myelocyte (Granulocyte) normal tissue (control) Spleen None (spontaneous) 1 not applicable
Leukocyte - Myelocyte (Granulocyte) tumor - malignant Leukocyte - Myelocyte (Granulocyte) Chemical/Drug 1 0
Leukocyte leukemia Leukocyte None (spontaneous) 6 0 - 16
Leukocyte leukemia Leukocyte Virus 2 0
Leukocyte leukemia Leukocyte Chemical/Drug 1 20
Leukocyte leukemia Leukocyte Radiation 2 0
Leukocyte lymphoma Leukocyte None (spontaneous) 10 0 - 57
Leukocyte lymphoma Leukocyte Diet 1 0
Leukocyte lymphoma Kidney None (spontaneous) 3 0 - 14
Leukocyte lymphoma Lung None (spontaneous) 3 0 - 20
Leukocyte lymphoma Thymus None (spontaneous) 1 0
Leukocyte lymphoma Spleen None (spontaneous) 3 0 - 12
Leukocyte lymphoma Liver None (spontaneous) 5 6.0 - 8
Leukocyte lymphoma Pancreas None (spontaneous) 1 0
Leukocyte lymphoma Lymph node None (spontaneous) 1 15
Leukocyte lymphoma Kidney Diet 5 0 - 6.7
Leukocyte lymphoma Lung Diet 5 0 - 2.0
Leukocyte lymphoma Thymus Diet 1 3.3
Leukocyte lymphoma Spleen Diet 5 0 - 6.7
Leukocyte lymphoma Liver Diet 5 0 - 10
Leukocyte lymphoma Pancreas Diet 1 0
Leukocyte lymphoma Lymph node Diet 1 10
Leukocyte lymphoma Leukocyte Radiation 2 5.3 - 21
Leukocyte lymphoma Heart None (spontaneous) 2 0
Leukocyte lymphoma Heart Diet 4 0
Leukocyte lymphoma - lymphosarcoma Leukocyte None (spontaneous) 2 0
Leukocyte lymphoma - lymphosarcoma Leukocyte Radiation 2 0 - 5.3
Leukocyte neoplasia Leukocyte None (spontaneous) 1 67
Liver - Bile duct adenoma Liver - Bile duct None (spontaneous) 2 0
Liver - Bile duct cyst - macrocyst Liver - Bile duct None (spontaneous) 2 0
Liver - Bile duct hyperplasia Liver - Bile duct None (spontaneous) 2 0
Liver - Hepatocyte foci - basophilic Liver - Hepatocyte Chemical/Drug 2 observed
Liver - Hepatocyte foci - eosinophilic Liver - Hepatocyte Chemical/Drug 1 observed
Liver adenoma Liver None (spontaneous) 1 1
Liver carcinoma Liver None (spontaneous) 2 0 - 2.0
Liver carcinoma Liver Diet 4 0
Liver cyst Liver None (spontaneous) 3 0 - 3
Liver cyst Liver Diet 4 0
Liver cyst - macrocyst Liver None (spontaneous) 2 0 - 2
Liver cystadenoma Liver None (spontaneous) 2 0
Liver cystadenoma Liver Radiation 2 0 - 14
Liver foci - clear cell Liver None (spontaneous) 2 0 - 2
Liver foci - eosinophilic Liver None (spontaneous) 2 0 - 2
Liver foci - vacuolated cell Liver None (spontaneous) 2 0
Liver hepatoblastoma Liver None (spontaneous) 1 observed
Liver hepatocellular adenoma Liver Chemical/Drug 1 observed
Liver hepatocellular adenoma Liver None (spontaneous) 2 0 - 2
Liver hepatocellular carcinoma Liver None (spontaneous) 5 0 - 8.8
Liver hepatocellular carcinoma Liver Chemical/Drug 4 0 - 26.67
Liver hepatocellular carcinoma Liver Other 3 observed - 8.75
Liver hepatocellular carcinoma Liver Diet 1 observed
Liver hepatoma Liver None (spontaneous) 2 0
Liver hyperplasia Liver None (spontaneous) 2 3 - 15.45
Liver hyperplasia Liver Other 1 75
Liver lesion Liver None (spontaneous) 2 0 - 12
Liver lesion Liver Diet 4 0 - 26
Liver neoplasm Liver None (spontaneous) 4 0 - 4
Liver normal tissue (control) Liver None (spontaneous) 3 not applicable
Liver tumor Liver Chemical/Drug 1 observed
Liver tumor Liver None (spontaneous) 6 0 - 30
Lung adenocarcinoma Lung None (spontaneous) 1 3
Lung adenoma Lung Chemical/Drug 8 observed - 100
Lung adenoma Lung None (spontaneous) 12 0 - very low
Lung adenoma Lung Diet 4 0
Lung carcinoma Lung None (spontaneous) 1 11
Lung carcinoma Lung Chemical/Drug 1 0
Lung hyperplasia Lung None (spontaneous) 2 0
Lung neoplasm Lung None (spontaneous) 4 2 - 8
Lung normal tissue (control) Lung None (spontaneous) 3 not applicable
Lung tumor Lung None (spontaneous) 5 0 - 3
Lung tumor Lung Radiation 4 0
Lung tumor Lung Chemical/Drug 8 observed - 100
Lung tumor - malignant Lung None (spontaneous) 2 2.0 - 4.0
Lung tumor - malignant Lung Diet 4 0 - 2.0
Lymph node cyst Lymph node None (spontaneous) 2 0
Lymph node hyperplasia Reticulocyte None (spontaneous) 2 0
Lymph node normal tissue (control) Lymph node None (spontaneous) 1 not applicable
Mammary gland adenocarcinoma Mammary gland None (spontaneous) 3 0 - 1
Mammary gland adenocarcinoma - intraductal Mammary gland None (spontaneous) 1 observed
Mammary gland neoplasm Mammary gland None (spontaneous) 2 0
Mammary gland normal tissue (control) Mammary gland None (spontaneous) 4 not applicable
Mammary gland tumor Mammary gland None (spontaneous) 4 0 - 1
Mesodermal cell/mesoblast myxosarcoma Muscle - Striated - Skeletal None (spontaneous) 2 0
Mesodermal cell/mesoblast sarcoma Intestine - Small Intestine - Brunner's gland None (spontaneous) 1 observed
Mesodermal cell/mesoblast sarcoma Liver None (spontaneous) 1 observed
Mesodermal cell/mesoblast sarcoma Peritoneal cavity None (spontaneous) 2 0
Mesodermal cell/mesoblast sarcoma Seminal vesicle None (spontaneous) 1 0
Mesodermal cell/mesoblast sarcoma Stomach - Glandular None (spontaneous) 2 0
Mesodermal cell/mesoblast sarcoma Urinary bladder None (spontaneous) 2 0
Mesodermal cell/mesoblast sarcoma - round cell Lung None (spontaneous) 1 0
Mesodermal cell/mesoblast sarcoma - round cell Liver None (spontaneous) 1 7.7
Mesodermal cell/mesoblast sarcoma - round cell Lymph node None (spontaneous) 1 7.7
Mesodermal cell/mesoblast sarcoma - round cell Lung Diet 1 3.3
Mesodermal cell/mesoblast sarcoma - round cell Liver Diet 1 6.7
Mesodermal cell/mesoblast sarcoma - round cell Lymph node Diet 1 6.7
Mesodermal cell/mesoblast sarcoma - stromal Uterus - Endometrium - Stroma None (spontaneous) 1 0
Mesothelium foci Mesothelium Chemical/Drug 1 18.18
Mesothelium mesothelioma Mesothelium Chemical/Drug 3 86.67 - 100
Mesothelium mesothelioma Mesothelium None (spontaneous) 1 0
Mesothelium mesothelioma - malignant - sarcomatoid Mesothelium Chemical/Drug 1 18.18
Mesothelium tumor - benign Mesothelium Chemical/Drug 1 45.45
Mouth - Oral mucosa cyst Mouth - Oral mucosa None (spontaneous) 2 0
Muscle - Smooth leiomyoma Vagina None (spontaneous) 1 0
Muscle - Smooth leiomyosarcoma Intestine - Large Intestine - Cecum None (spontaneous) 2 0
Muscle - Smooth leiomyosarcoma Muscle - Smooth None (spontaneous) 3 0 - 3
Muscle - Smooth leiomyosarcoma Seminal vesicle None (spontaneous) 1 4
Muscle - Smooth leiomyosarcoma Intestine - Large Intestine - Colon None (spontaneous) 1 1
Muscle - Striated - Skeletal normal tissue (control) Muscle - Striated - Skeletal None (spontaneous) 2 not applicable
Muscle - Striated - Skeletal rhabdomyosarcoma Muscle - Striated - Skeletal None (spontaneous) 2 0
Muscle - Striated - Skeletal rhabdomyosarcoma - pleomorphic Muscle - Striated - Skeletal None (spontaneous) 1 0
Myoepithelial cell myoepithelioma Lung None (spontaneous) 2 0
Myoepithelial cell myoepithelioma Mammary gland None (spontaneous) 2 0
Nail dysplasia Nail None (spontaneous) 1 observed
Nail squamous cell carcinoma Nail None (spontaneous) 3 0 - observed
Nerve normal tissue (control) Nerve None (spontaneous) 2 not applicable
Oral cavity normal tissue (control) Oral cavity None (spontaneous) 2 not applicable
Ovary - Follicle cyst - follicular Ovary - Follicle None (spontaneous) 1 low
Ovary - Granulosa cell tumor Ovary - Granulosa cell None (spontaneous) 3 0 - 2
Ovary - Granulosa cell tumor Ovary - Granulosa cell Radiation 1 5.3
Ovary - Luteal cell tumor Ovary - Luteal cell None (spontaneous) 1 0
Ovary - Sex cord stromal cell adenoma - tubulostromal Ovary - Sex cord stromal cell None (spontaneous) 2 observed
Ovary adenoma Ovary None (spontaneous) 1 0
Ovary cyst Ovary None (spontaneous) 1 4
Ovary cyst - bursal Ovary None (spontaneous) 1 0
Ovary cystadenoma Ovary None (spontaneous) 1 0
Ovary cystadenoma Ovary Radiation 1 42
Ovary hyperplasia - epithelial Ovary None (spontaneous) 1 0
Ovary luteoma Ovary None (spontaneous) 1 observed
Ovary neoplasm Ovary None (spontaneous) 1 1
Ovary tumor Ovary None (spontaneous) 1 0
Ovary tumor Ovary Radiation 1 47
Ovary tumor Ovary Other 1 observed
Ovary tumor - tubulostromal Ovary None (spontaneous) 1 0
Oviduct hyperplasia Oviduct None (spontaneous) 2 observed
Oviduct normal tissue (control) Oviduct None (spontaneous) 2 not applicable
PNS - Nerve sheath tumor Ear None (spontaneous) 2 0
PNS - Nerve sheath tumor Skin None (spontaneous) 2 0
Pancreas - Duct adenoma Pancreas - Duct None (spontaneous) 2 0
Pancreas - Islet of Langerhans - Beta cell tumor Pancreas - Islet of Langerhans - Beta cell None (spontaneous) 1 0
Pancreas - Islet of Langerhans hyperplasia Pancreas - Islet of Langerhans None (spontaneous) 3 observed
Pancreas neoplasm Pancreas None (spontaneous) 2 0
Pancreas normal tissue (control) Pancreas None (spontaneous) 3 not applicable
Pancreas tumor Pancreas Other 1 observed
Peritoneum - Mesentery hyperplasia Peritoneum - Mesentery None (spontaneous) 1 observed
Peyer's patch normal tissue (control) Peyer's patch None (spontaneous) 1 not applicable
Pituitary gland - Pars distalis adenocarcinoma Pituitary gland - Pars distalis None (spontaneous) 1 1
Pituitary gland - Pars distalis adenoma Pituitary gland - Pars distalis None (spontaneous) 3 0 - 31
Pituitary gland - Pars distalis adenoma Pituitary gland - Pars distalis Diet 1 3.3
Pituitary gland - Pars distalis cyst - microcyst Pituitary gland - Pars distalis None (spontaneous) 2 0 - 2
Pituitary gland - Pars distalis hyperplasia - focal Pituitary gland - Pars distalis None (spontaneous) 2 0 - 12
Pituitary gland - Pars distalis tumor Pituitary gland - Pars distalis None (spontaneous) 3 0 - 83
Pituitary gland - Pars intermedia adenoma Pituitary gland - Pars intermedia None (spontaneous) 3 0 - observed
Pituitary gland - Pars intermedia hyperplasia Pituitary gland - Pars intermedia None (spontaneous) 2 0 - 4
Pituitary gland adenoma Pituitary gland None (spontaneous) 2 0 - 6
Pituitary gland carcinoma Pituitary gland None (spontaneous) 2 0 - 2
Pituitary gland cyst - microcyst Pituitary gland None (spontaneous) 2 2
Pituitary gland hyperplasia Pituitary gland None (spontaneous) 1 observed
Pituitary gland hyperplasia - focal Pituitary gland None (spontaneous) 2 0
Pituitary gland neoplasm Pituitary gland None (spontaneous) 4 0 - 7
Pituitary gland tumor Pituitary gland None (spontaneous) 9 0 - 61
Pituitary gland tumor Pituitary gland Hormone 1 very low
Placenta normal tissue (control) Placenta None (spontaneous) 3 not applicable
Preputial/Clitoral gland (sex not specified) normal tissue (control) Preputial/Clitoral gland (sex not specified) None (spontaneous) 3 not applicable
Prostate gland - Anterior lobe adenocarcinoma Prostate gland - Anterior lobe None (spontaneous) 1 0
Prostate gland normal tissue (control) Prostate gland None (spontaneous) 1 not applicable
Prostate gland prostatic intraepithelial neoplasia (PIN) Prostate gland None (spontaneous) 1 observed
Salivary gland - Parotid hyperplasia Salivary gland - Parotid None (spontaneous) 1 observed
Salivary gland normal tissue (control) Salivary gland None (spontaneous) 3 not applicable
Seminal vesicle normal tissue (control) Seminal vesicle None (spontaneous) 1 not applicable
Skin - Dorsal region adenoma - sebaceous Skin - Dorsal region None (spontaneous) 1 observed
Skin - Dorsal region papilloma Skin - Dorsal region None (spontaneous) 1 observed
Skin - Dorsal region tumor Skin - Dorsal region Virus 1 0
Skin - Epidermis - Basal cell carcinoma Skin - Epidermis - Basal cell None (spontaneous) 2 0
Skin - Epidermis cyst - inclusion Skin - Epidermis None (spontaneous) 2 0
Skin - Epidermis hamartoma Skin - Epidermis None (spontaneous) 1 observed
Skin - Epidermis hyperplasia Skin - Epidermis None (spontaneous) 1 observed
Skin - Facial region tumor Skin - Facial region Virus 1 0
Skin - Hair follicle hyperplasia Skin - Hair follicle None (spontaneous) 1 observed
Skin - Tail tumor Skin - Tail Virus 1 0
Skin - Vibrissa squamous cell carcinoma in situ Skin - Vibrissa None (spontaneous) 2 0
Skin gland - Sweat gland hyperplasia Ear - Outer ear - Ear canal None (spontaneous) 2 0
Skin hyperplasia Skin None (spontaneous) 5 observed
Skin hyperplasia - epithelial Ear None (spontaneous) 2 0
Skin hyperplasia - epithelial Eye - Eyelid None (spontaneous) 2 0
Skin lesion Skin Chemical/Drug 1 observed
Skin lesion Skin Virus 1 0
Skin normal tissue (control) Skin None (spontaneous) 5 not applicable
Skin papilloma Skin Chemical/Drug 1 very high
Skin squamous cell carcinoma Skin None (spontaneous) 2 observed - 1
Skin tumor Skin Chemical/Drug 1 42
Skin tumor Skin None (spontaneous) 2 0 - 11
Spleen normal tissue (control) Spleen None (spontaneous) 2 not applicable
Spleen tumor Spleen None (spontaneous) 2 0 - 6.0
Spleen tumor Spleen Diet 4 0 - 10
Spleen tumor - round cell Spleen None (spontaneous) 1 0
Spleen tumor - round cell Spleen Diet 1 0
Stomach - Epithelium hyperplasia - squamous Stomach - Epithelium None (spontaneous) 1 observed
Stomach - Glandular adenoma Stomach - Glandular None (spontaneous) 2 0 - low
Stomach - Glandular cyst Stomach - Glandular None (spontaneous) 2 0
Stomach - Glandular cyst - glandular Stomach - Glandular None (spontaneous) 2 0
Stomach - Glandular hyperplasia Stomach - Glandular None (spontaneous) 2 0 - low
Stomach - Glandular hyperplasia - adenomatous Stomach - Glandular None (spontaneous) 2 0 - low
Stomach - Glandular normal tissue (control) Stomach - Glandular None (spontaneous) 1 not applicable
Stomach - Glandular polyp Stomach - Glandular None (spontaneous) 2 0
Stomach adenocarcinoma Stomach None (spontaneous) 1 0
Stomach adenoma Stomach None (spontaneous) 1 0
Stomach normal tissue (control) Stomach None (spontaneous) 2 not applicable
Stomach squamous cell papilloma Stomach None (spontaneous) 1 3
Testis - Germ cell normal tissue (control) Testis - Germ cell None (spontaneous) 1 not applicable
Testis - Leydig cell (Interstitial cell) adenoma Testis - Leydig cell (Interstitial cell) None (spontaneous) 1 4
Testis - Leydig cell (Interstitial cell) cyst Testis - Leydig cell (Interstitial cell) None (spontaneous) 1 0
Testis - Leydig cell (Interstitial cell) hyperplasia Testis - Leydig cell (Interstitial cell) None (spontaneous) 1 0
Testis - Leydig cell (Interstitial cell) normal tissue (control) Testis - Leydig cell (Interstitial cell) None (spontaneous) 1 not applicable
Testis - Leydig cell (Interstitial cell) tumor Testis - Leydig cell (Interstitial cell) None (spontaneous) 1 0
Testis normal tissue (control) Testis None (spontaneous) 1 not applicable
Thymus normal tissue (control) Thymus None (spontaneous) 3 not applicable
Thyroid gland - Follicular cell cyst Thyroid gland - Follicular cell None (spontaneous) 3 observed
Thyroid gland - Follicular cell hyperplasia Thyroid gland - Follicular cell None (spontaneous) 1 observed
Thyroid gland adenoma Thyroid gland None (spontaneous) 2 observed
Thyroid gland hyperplasia - cystic Thyroid gland None (spontaneous) 4 0 - low
Thyroid gland neoplasm Thyroid gland None (spontaneous) 2 0
Tongue normal tissue (control) Tongue None (spontaneous) 5 not applicable
Tooth dysplasia Tooth None (spontaneous) 3 observed
Trachea normal tissue (control) Trachea None (spontaneous) 3 not applicable
Ureter - Transitional cell hyperplasia Ureter - Transitional cell None (spontaneous) 2 0
Ureter hyperplasia Ureter None (spontaneous) 1 observed
Ureter hyperplasia Muscle - Smooth None (spontaneous) 2 0
Ureter polyp Ureter None (spontaneous) 2 0 - very low
Urinary bladder - Transitional cell atypia Urinary bladder - Transitional cell None (spontaneous) 2 0
Urinary bladder - Transitional cell normal tissue (control) Urinary bladder - Transitional cell None (spontaneous) 1 not applicable
Urinary bladder normal tissue (control) Urinary bladder None (spontaneous) 3 not applicable
Urinary bladder papilloma Urinary bladder None (spontaneous) 2 0
Uterus - Endometrium hyperplasia - cystic Uterus - Endometrium None (spontaneous) 4 observed - moderate
Uterus - Endometrium normal tissue (control) Uterus - Endometrium None (spontaneous) 2 not applicable
Uterus adenoma Uterus None (spontaneous) 1 0
Uterus fibropapilloma Uterus None (spontaneous) 1 0
Uterus neoplasm Uterus None (spontaneous) 1 4
Uterus normal tissue (control) Uterus None (spontaneous) 3 not applicable
Vagina normal tissue (control) Vagina None (spontaneous) 1 not applicable
Vagina papilloma Vagina None (spontaneous) 1 0
Vulva squamous cell carcinoma Vulva None (spontaneous) 1 0
(Unspecified organ) neoplasm (Unspecified organ) None (spontaneous) 4 35 - 50
(Unspecified organ) reticulum cell sarcoma (Unspecified organ) None (spontaneous) 1 9
(Unspecified organ) tumor (Unspecified organ) None (spontaneous) 7 0 - low
(Unspecified organ) tumor (Unspecified organ) Chemical/Drug 1 2.4
(Unspecified organ) tumor (Unspecified organ) Radiation 2 36 - 58
(Unspecified organ) tumor (Unspecified organ) Other 1 observed
Other Database Links
Additional information about these mice:
Mouse Phenome Database (MPD) http://phenome.jax.org/db/q?rtn=strains/details&strainid=7
Festing's List of Inbred Strains http://www.informatics.jax.org/external/festing/mouse/docs/C57BL.shtml
JAX Mice http://jaxmice.jax.org/strain/000664.html