Pathology Image Detail

Caption

Liver: the neoplasm is composed of 2-3 cells-thick trabeculae separated by tortuous sinusoids. Neoplastic cells are large, polygonal, with indistinct cell borders, and with a moderate amount of strongly acidophilic cytoplasm which contains numerous ill-defined optically-empty vacuoles. The nucleus is central, large, generally oval, hyperchromatic, with a coarsely clumped chromatin and 1-3 small basophilic nucleoli. Anisocytosis is moderate. Anisokaryosis is marked. Mitoses are not found.

Description

Hepatocellular adenoma, liver

Age at Necropsy

588 days

Contributor

Mikaelian I (J:94320)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:25815
Tumor Name
Liver • hepatocellular adenoma
Treatment Type
None (spontaneous)
Tumor Synonyms
liver, hepatocellular adenoma
Organ Affected
Liver
Frequency
observed
Reference
J:94320

Strain

Strain
C3H/HeJ
Strain Types
inbred
Strain Synonyms
C3H/HeJ-MTV+
C3H The Jackson Laboratory
C3H/HeJ, H-2k
C3H
C3H/He
C3H/HeJ MMTV-
C3H Heston
C3
C3H/HeJ mtv+
MTV+
Strain Sex
Male
Reproductive Status
reproductive status not specified
Age of Detection
588 days