Pathology Image Detail

Caption

Vertebra: the vertebral body is replaced by a nodular, expansile, moderately to poorly cellular encapsulated neoplastic mass. This neoplasm is predominantly composed of a pale acidophilic chondromatous matrix in which a small to moderate number of oval to stellate-shaped neoplastic cells are embedded. Within this matrix and at it's periphery, neoplastic cells are clustered around trabeculae of mineralized osteoid.

Description

Osteosarcoma, chondroblastic, bone, vertebra

Age at Necropsy

224 days

Contributor

Mikaelian I (J:94320)

Pathologist

Mikaelian I (J:94320)

Method

H&E

Model

MMHC ID
MTB:25816
Tumor Name
Bone - Vertebral column - Vertebra • osteosarcoma - chondroblastic
Treatment Type
None (spontaneous)
Tumor Synonyms
osteosarcoma, chondroblastic, bone, vertebra
Organ Affected
Bone - Vertebral column - Vertebra
Frequency
observed
Reference
J:94320

Strain

Strain
C57BL/6J
Strain Types
inbred
Strain Synonyms
wild-type C57BL/6J
C57Bl/6J
p53+/+
C57BL/6 from Jackson Laboratory
C57BL/6
B6
C57/Bl6
C57
C57BL/6J (F129+51)
C57 black subline 6
B/6
Bl/6
C57BL/6J wild-type
WT
Black 6
C57 Black
wild type
C57BL/6J+/+
p53 wild-type (+/+)
C57BL6/J
C57BL/6J, H-2b
C57/B16
wild-type
C57BL
B6 WT
wild-type (WT)
WT-Control
WT-CR
C57/Bl 6J
C57/Bl
p21+/+p27+/+
control
Ctr
C57BL/6J (UW)
B6J
C57BL/6J inbred WT
C57 BL/6
Wild-type (WT) C57BL/6J
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
224 days