Pathology Image Detail

Caption

Eye - Cornea - Normal tissue. There is strong cytoplasmic labeling of rafts and scattered basal cells (antibody diluted at 1:100, tissue fixed in Bouin's solution). There is also moderate background in the stroma of the cornea. Other tissues were not labeled. This pattern of labeling was interpreted as an artifact because simple epithelial did not label with this antibody and because the corneal epithelium is prone to false-positive labeling.

Description

Eye - Cornea - Normal tissue. Keratin 18, immunohistochemistry, non-specific staining

Age at Necropsy

35 days

Contributor

Mikaelian I (J:94320)

Pathologist

Mikaelian I (J:94320)

Method

IHC for keratin 18
Image Probes

Type: antibody

Name
anti-keratin 18 (MAB1600)
Target
human keratin 18
Supplier
Chemicon
Notes
Mouse IgG1 monocolonal antibody.

Model

MMHC ID
MTB:27643
Tumor Name
Eye - Cornea • normal tissue (control)
Treatment Type
None (spontaneous)
Tumor Synonyms
cornea, normal tissue
Organ Affected
Eye - Cornea
Frequency
not applicable
Reference
J:94320

Strain

Strain
C57BL/6J
Strain Types
inbred
Strain Synonyms
wild-type C57BL/6J
C57Bl/6J
p53+/+
C57BL/6 from Jackson Laboratory
C57BL/6
B6
C57/Bl6
C57
C57BL/6J (F129+51)
C57 black subline 6
B/6
Bl/6
C57BL/6J wild-type
WT
Black 6
C57 Black
wild type
C57BL/6J+/+
p53 wild-type (+/+)
C57BL6/J
C57BL/6J, H-2b
C57/B16
wild-type
C57BL
B6 WT
wild-type (WT)
WT-Control
WT-CR
C57/Bl 6J
C57/Bl
p21+/+p27+/+
control
Ctr
C57BL/6J (UW)
B6J
C57BL/6J inbred WT
C57 BL/6
Wild-type (WT) C57BL/6J
Strain Sex
Unspecified
Reproductive Status
reproductive status not specified
Age of Detection
35 days