Pathology Image Detail

Caption	Oral mucosa (tongue) - normal tissue. There is strong labeling for keratins 5/8 of suprabasal cells of the inter-papillary mucosa (antibody diluted at 1:500, tissue fixed in Fekete's solution, enzymatic digestion in trypsin). Keratin 5 is a marker of basal cells while keratin 8 is a marker of simple epithelia. Hence labeling in this case is interpreted as the result of a cross-reaction of the antibody with undetermined proteins.
Description	Tongue - Normal tissue. Keratins 5 and 8 immunohistochemistry, non-specific labeling
Age at Necropsy	35 days
Contributor	Mikaelian I (J:94320)
Pathologist	Mikaelian I (J:94320)
Method	IHC for keratin 5 and 8

Image Probes
Type: antibody	Name anti-keratin 5 and 8 (MAB1629) Target human keratin 5 and 8 Supplier Chemicon Notes Specificity: Human keratins 5 (58 kD) and 8 (52.5 kD). MAB1629 cross-reacts with many mammalian species. Negative on chicken and Xenopus.

Strain Synonyms: wild-type C57BL/6J; C57Bl/6J; p53+/+; C57BL/6 from Jackson Laboratory; C57BL/6; B6; C57/Bl6; C57; C57BL/6J (F₁₂₉₊₅₁); C57 black subline 6; B/6; Bl/6; C57BL/6J wild-type; WT; Black 6; C57 Black; wild type; C57BL/6J^+/+; p53 wild-type (+/+); C57BL6/J; C57BL/6J, H-2^b; C57/B16; wild-type; C57BL; B6 WT; wild-type (WT); WT-Control; WT-CR; C57/Bl 6J; C57/Bl; p21+/+p27+/+; control; Ctr; C57BL/6J (UW); B6J; C57BL/6J inbred WT; C57 BL/6; Wild-type (WT) C57BL/6J