Pathology Image Detail

Caption

Mammary gland, adenocarcinoma, with squamous metaplasia.
Pan-cadherin expression is absent throughout the neoplasm except in an area of squamous metaplasia.

Description

Mammary gland, adenocarcinoma, with squamous metaplasia.

Age at Necropsy

210 days

Contributor

Mikaelian I (J:94310)

Pathologist

Mikaelian I (J:94310)

Method

IHC for pan-cadherin
Image Probes

Type: antibody

Name
anti-pancadherin (C3678)
Target
chicken N-cadherin, N-terminus
Supplier
Sigma-Aldrich
Notes
Polyclonal rabbit antiserum raised against a synthetic peptide corresponding to the C-terminal amino acids of chicken N-Cadherin with an extra N-terminal lysine residue (24 amino acids).

Model

MMHC ID
MTB:18035
Tumor Name
Mammary gland • adenocarcinoma
Treatment Type
None (spontaneous)
Tumor Synonyms
mammary adenocarcinoma
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94310

Strain

Strain
C3H/HeJ
Strain Types
inbred
Strain Synonyms
C3H/HeJ-MTV+
C3H The Jackson Laboratory
C3H/HeJ, H-2k
C3H
C3H/He
C3H/HeJ MMTV-
C3H Heston
C3
C3H/HeJ mtv+
MTV+
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
210 days