Pathology Image Detail

Caption	Mammary gland, adenocarcinoma. Neoplastic cells at the periphery of neoplastic lobules intensely label for alpha smooth muscle actin, which indicates myoepithelial differentiation. This picture is taken from an area where the neoplasm had a solid to comedo-type pattern.
Description	Mammary gland, adenocarcinoma.
Age at Necropsy	173 days
Contributor	Mikaelian I (J:94310)
Pathologist	Mikaelian I (J:94310)
Method	IHC for alpha smooth muscle actin

Image Probes
Type: antibody	Name anti-alpha smooth muscle actin (A2547) Target alpha-smooth muscle actin, N-terminus Supplier Sigma-Aldrich Notes Monoclonal anti-Alpha Smooth Muscle Actin antibody produced in mouse (raised against N-terminal synthetic decapeptide of alpha-smooth muscle actin). The antibody (also known as anti-a-Sm-1) is specific for the single isoform of alpha-smooth muscle actin.

Strain Synonyms: C3H/HeJ-MTV⁺; C3H The Jackson Laboratory; C3H/HeJ, H-2^k; C3H; C3H/He; C3H/HeJ MMTV^-; C3H Heston; C3; C3H/HeJ mtv+; MTV⁺