Pathology Image Detail

Caption	Mammary gland, adenocarcinoma. Neoplastic cells at the periphery of large lobules in an area with a comedo pattern strongly label for alpha smooth muscle actin. A few neoplastic cells scattered throughout neoplastic lobules show moderate labeling.
Description	Mammary gland, adenocarcinoma.
Age at Necropsy	173 days
Contributor	Mikaelian I (J:94310)
Pathologist	Mikaelian I (J:94310)
Method	IHC for alpha smooth muscle actin

Image Probes
Type: antibody	Name anti-alpha smooth muscle actin (A2547) Target alpha-smooth muscle actin, N-terminus Supplier Sigma-Aldrich Notes Monoclonal anti-Alpha Smooth Muscle Actin antibody produced in mouse (raised against N-terminal synthetic decapeptide of alpha-smooth muscle actin). The antibody (also known as anti-a-Sm-1) is specific for the single isoform of alpha-smooth muscle actin.

Strain Synonyms: C3H/HeJ-MTV⁺; C3H The Jackson Laboratory; C3H/HeJ, H-2^k; C3H; C3H/He; C3H/HeJ MMTV^-; C3H Heston; C3; C3H/HeJ mtv+; MTV⁺