Pathology Image Detail

Caption

 Mammary gland, adenocarcinoma. This is a high magnification picture of an area of a mammary adenocarcinoma which displays acinar and solid patterns concurrently. Immunolabeling is restricted to the areas of acinar differentiation and generally is restricted to the apical cellular membrane of neoplastic cells. In addition, the cytoplasm of a few neoplastic cells is intensely labeled for MMTV nucleoid protein p27.

Description

 Mammary gland, adenocarcinoma.

Age at Necropsy

 186 days

Contributor

 Mikaelian I (J:94310)

Pathologist

 Mikaelian I (J:94310)

Method

 IHC for MMTV nucleoid protein p27
Image Probes

Type: antibody
Name
anti-MMTV nucleoid protein p27
Target
MMTV nucleoid protein p27
Supplier
Tatyana Golovkina, The Jackson Laboratory
Notes
Antibody: mouse monoclonal anti-MMTV nucleoid protein p27 (Tatyana Golovkina, Clone Blue 7-1)

Model
MMHC ID
MTB:18036
Tumor Name
Mammary gland • adenocarcinoma
Treatment Type
None (spontaneous)
Tumor Synonyms
mammary adenocarcinoma
Organ Affected
Mammary gland
Frequency
observed
Reference
J:94310

Strain
Strain
C3H/HeJ
Strain Types
inbred
Strain Synonyms
C3H/HeJ-MTV+
C3H The Jackson Laboratory
C3H/HeJ, H-2k
C3H
C3H/He
C3H/HeJ MMTV-
C3H Heston
C3
C3H/HeJ mtv+
MTV+
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
186 days