Pathology Image Detail
Caption |
This is a 40x image. |
Description |
rhabdomyosarcoma |
Age at Necropsy |
536 days |
Notes |
This is a rhabdomyosarcoma in a 536 day old female mouse. This strain of mice develop rhabdomyosarcoma as they age in relatively high frequency. Note the pleomorphism of the cell population. Cross striations can be found in some of the better differentiated cells, which are best visualized using special stains. Straited muscle actin immunohistochemistry is further confirmation of the diagnosis. Rhabdomyosarcoma is in the spinal cord. The rhabdomyosarcoma invaded into and through the vertebral bodies, into the spinal canal, and compressed the spinal cord. |
Contributor |
Sundberg J (J:122261) |
Pathologist |
Sundberg J (J:122261) |
Copyright |
This image was submitted by JP Sundberg, the Jackson Laboratory. This image is from Sher RB, PLOS ONE 2011; Vol 6, Issue 8, e23498, an open-access article distributed under the terms of the Creative Commons Attribution License. |
Model |
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Strain |
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