Pathology Image Detail

Caption

 The pancreatic lymph node has been entirely replaced by a densely cellular neoplasm made of closely packed sheets of neoplastic lymphocytes. The pancreas is not infiltrated by neoplastic cells.

Description

 Pancreatic lymph node, lymphoma.

Age at Necropsy

 108 days

Contributor

 Mikaelian I (J:94314)

Pathologist

 Mikaelian I (J:94314)

Method

 H&E

Model
MMHC ID
MTB:18474
Tumor Name
Leukocyte - Lymphocyte • lymphoma
Treatment Type
None (spontaneous)
Tumor Synonyms
lymphoma
Organ Affected
Lymph node
Frequency
observed
Reference
J:94314

Strain
Strain
C.129S2(B6)-Trp53tm1Tyj/J
Strain Types
congenic
targeted mutation (knockout)
General Note
Homozygous mice. These mice have been fully backcrossed onto BALB/cJ. The original mutation was generated using 129S2/SvPas ES cells and was crossed to C57BL/6 before being backcrossed to BALB/cJ.
Strain Synonyms
BALB/cJ-Trp53tm1Tyj
C.129S2(B6)-Trp53tm1Tyj
C.129S2-Trp53tm1Tyj/J
p53&delta
BALB-p53?/?
p53-/-
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
108 days