Pathology Image Detail

Caption

Bone marrow - normal tissue. There is strong nuclear immunolabeling of numerous cells scattered throughout the bone marrow (antibody diluted at 1:100, tissues fixed in 4% paraformaldehyde and decalcified for 2 hours, heat-mediated antigen retrieval in citrate buffer at pH=6.0). The tissue was decalcified, which has altered its' cytologic features.

Description

Bone marrow - normal tissue. Cdkn2b [p15] immunohistochemistry

Age at Necropsy

35 days

Contributor

Mikaelian I (J:94320)

Pathologist

Mikaelian I (J:94320)

Method

IHC for p15 [Cdkn2b] [INK 4b]
Image Probes

Type: antibody

Name
anti-p15 (M-20) (sc-1429)
Target
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4) (Cdkn2b)
Supplier
Santa Cruz Biotechnology
Notes
Goat polyclonal IgG. Epitope mapping at the C-terminus of Cdkn2b [p15] [INK 4B] of mouse origin.

Model

MMHC ID
MTB:27628
Tumor Name
Bone marrow • normal tissue (control)
Treatment Type
None (spontaneous)
Tumor Synonyms
bone marrow, normal tissue
Organ Affected
Bone marrow
Frequency
not applicable
Reference
J:94320

Strain

Strain
C57BL/6J
Strain Types
inbred
Strain Synonyms
wild-type C57BL/6J
C57Bl/6J
p53+/+
C57BL/6 from Jackson Laboratory
C57BL/6
B6
C57/Bl6
C57
C57BL/6J (F129+51)
C57 black subline 6
B/6
Bl/6
C57BL/6J wild-type
WT
Black 6
C57 Black
wild type
C57BL/6J+/+
p53 wild-type (+/+)
C57BL6/J
C57BL/6J, H-2b
C57/B16
wild-type
C57BL
B6 WT
wild-type (WT)
WT-Control
WT-CR
C57/Bl 6J
C57/Bl
p21+/+p27+/+
control
Ctr
C57BL/6J (UW)
B6J
C57BL/6J inbred WT
C57 BL/6
Wild-type (WT) C57BL/6J
Strain Sex
Unspecified
Reproductive Status
reproductive status not specified
Age of Detection
35 days