Pathology Image Detail

Caption

CNS - Brain - Choroid plexus - normal tissue. Central nervous system, gray matter: there is moderate labeling of all endothelial cells for integrin beta 1 (1:50 dilution, tissues fixed in IHC Zinc fixative, heat-mediated epitope retrieval in citrate buffer at pH=6.0). There is marked vacuolation of the neuropile, which is an artifact that commonly develops in tissues placed in 70% alcohol after fixation and prior to embedding.

Description

Brain, choroid plexus - Normal tissue. Beta 1 integrin immunohistochemistry.

Age at Necropsy

unknown

Contributor

Mikaelian I (J:94320)

Pathologist

Mikaelian I (J:94320)

Method

IHC for integrin beta 1 (CD29)
Image Probes

Type: antibody

Name
anti-integrin beta 1 (MAB1997)
Target
mouse integrin beta 1
Supplier
Chemicon
Notes
Rat antibody raised against mouse integrin beta 1 (CD29) protein

Model

MMHC ID
MTB:27632
Tumor Name
CNS - Brain - Choroid plexus • normal tissue (control)
Treatment Type
None (spontaneous)
Tumor Synonyms
choroid plexus, normal tissue
Organ Affected
CNS - Brain - Choroid plexus
Frequency
not applicable
Reference
J:94320

Strain

Strain
C57BL/6J
Strain Types
inbred
Strain Synonyms
wild-type C57BL/6J
C57Bl/6J
p53+/+
C57BL/6 from Jackson Laboratory
C57BL/6
B6
C57/Bl6
C57
C57BL/6J (F129+51)
C57 black subline 6
B/6
Bl/6
C57BL/6J wild-type
WT
Black 6
C57 Black
wild type
C57BL/6J+/+
p53 wild-type (+/+)
C57BL6/J
C57BL/6J, H-2b
C57/B16
wild-type
C57BL
B6 WT
wild-type (WT)
WT-Control
WT-CR
C57/Bl 6J
C57/Bl
p21+/+p27+/+
control
Ctr
C57BL/6J (UW)
B6J
C57BL/6J inbred WT
C57 BL/6
Wild-type (WT) C57BL/6J
Strain Sex
Unspecified
Reproductive Status
reproductive status not specified
Age of Detection
unknown