Pathology Image Detail

Caption

Haired skin - normal tissue. There is mild to moderate diffuse cytoplasmic labeling of the suprabasal layers of the epidermis, the outer root sheath of hair follicles, and of sebaceous glands (tissue fixed in 4% paraformaldehyde, heat-mediated antigen-retrieval in citrate buffer at pH=6.0, 1:100 dilution). Moderate nuclear labeling which is detected in a moderate number of cells of the outer root sheath and of sebaceous glands may represent an artifact.

Description

Haired skin - Normal tissue. JAK2 immunohistochemistry.

Age at Necropsy

unknown

Contributor

Mikaelian I (J:94320)

Pathologist

Mikaelian I (J:94320)

Method

IHC for JAK2
Image Probes

Type: antibody

Name
anti-JAK2 (06-255)
Target
Peptide corresponding to residues 758-776 of murine JAK2
Supplier
Upstate Biotechnology (now Millipore)
Notes
Species Reactivity: human, mouse and rat. Isotype: IgG. Host: Rabbit

Model

MMHC ID
MTB:27738
Tumor Name
Skin • normal tissue (control)
Treatment Type
None (spontaneous)
Tumor Synonyms
haired skin, normal tissue
Organ Affected
Skin
Frequency
not applicable
Reference
J:94320

Strain

Strain
C57BL/6J
Strain Types
inbred
Strain Synonyms
wild-type C57BL/6J
C57Bl/6J
p53+/+
C57BL/6 from Jackson Laboratory
C57BL/6
B6
C57/Bl6
C57
C57BL/6J (F129+51)
C57 black subline 6
B/6
Bl/6
C57BL/6J wild-type
WT
Black 6
C57 Black
wild type
C57BL/6J+/+
p53 wild-type (+/+)
C57BL6/J
C57BL/6J, H-2b
C57/B16
wild-type
C57BL
B6 WT
wild-type (WT)
WT-Control
WT-CR
C57/Bl 6J
C57/Bl
p21+/+p27+/+
control
Ctr
C57BL/6J (UW)
B6J
C57BL/6J inbred WT
C57 BL/6
Wild-type (WT) C57BL/6J
Strain Sex
Unspecified
Reproductive Status
reproductive status not specified
Age of Detection
unknown