Pathology Image Detail

Caption

Haired skin - normal tissue. This figure illustrates immunolabeling for keratin 1 (1:12,000 dilution) in a section of the skin fixed in neutral buffered formalin. There is moderate labeling of stratum spinosum. There is also moderate lymphocytic mural folliculitis, which is diagnosis for alopecia areata.

Description

Haired skin - Normal tissue. Keratin 1 immunohistochemistry.

Age at Necropsy

unknown

Contributor

Mikaelian I (J:94320)

Pathologist

Mikaelian I (J:94320)

Method

IHC for keratin 1
Image Probes

Type: antibody

Name
anti-keratin 1 (PRB-165P)
Target
mouse keratin 1, C-terminus
Supplier
Biolegend, formerlyCovance
Notes
Monospecific polyclonal rabbit antibody raised against a peptide sequence derived from the C-terminus of the mouse keratin 1 protein, VKTVSTYSRGTK.

Model

MMHC ID
MTB:27738
Tumor Name
Skin • normal tissue (control)
Treatment Type
None (spontaneous)
Tumor Synonyms
haired skin, normal tissue
Organ Affected
Skin
Frequency
not applicable
Reference
J:94320

Strain

Strain
C57BL/6J
Strain Types
inbred
Strain Synonyms
wild-type C57BL/6J
C57Bl/6J
p53+/+
C57BL/6 from Jackson Laboratory
C57BL/6
B6
C57/Bl6
C57
C57BL/6J (F129+51)
C57 black subline 6
B/6
Bl/6
C57BL/6J wild-type
WT
Black 6
C57 Black
wild type
C57BL/6J+/+
p53 wild-type (+/+)
C57BL6/J
C57BL/6J, H-2b
C57/B16
wild-type
C57BL
B6 WT
wild-type (WT)
WT-Control
WT-CR
C57/Bl 6J
C57/Bl
p21+/+p27+/+
control
Ctr
C57BL/6J (UW)
B6J
C57BL/6J inbred WT
C57 BL/6
Wild-type (WT) C57BL/6J
Strain Sex
Unspecified
Reproductive Status
reproductive status not specified
Age of Detection
unknown