Pathology Image Detail

Caption

Colon - normal tissue. There is strong labeling for Clara cell protein 26KD of the superficial portions of the colonic epithelium (antibody diluted at 1:800, tissue fixed in Fekete's solution, heat-mediated antigen retrieval in citrate buffer at pH=6.0).
NOTE: Possible causes for labeling of the optic nerve fibers layer suggests that the antibody for Clara cell protein 26KD is not specific or that this protein is not exclusively expressed in Clara cells. Alternatively, labeling of colonic cells may represent non-specific staining which is common for these cells and which is caused by the hydrophobic nature of their mucus droplet.

Description

Intestine - Large Intestine - Colon -Normal tissue. Clara cell protein 26KD immunohistochemistry

Age at Necropsy

35 days

Contributor

Mikaelian I (J:94320)

Pathologist

Mikaelian I (J:94320)

Method

IHC for Clara cell protein 26 KD
Image Probes

Type: antibody

Name
anti-Clara cell protein 26 KD (AB3700)
Target
Clara cell protein 26 kDa
Supplier
Chemicon
Notes
Rabbit polyclonal antibody. "Reacts with Human, Mouse, Rat. Reactivity with other species has not been confirmed."

Model

MMHC ID
MTB:27651
Tumor Name
Intestine - Large Intestine - Colon • normal tissue (control)
Treatment Type
None (spontaneous)
Tumor Synonyms
colon, normal tissue
Organ Affected
Intestine - Large Intestine - Colon
Frequency
not applicable
Reference
J:94320

Strain

Strain
C57BL/6J
Strain Types
inbred
Strain Synonyms
wild-type C57BL/6J
C57Bl/6J
p53+/+
C57BL/6 from Jackson Laboratory
C57BL/6
B6
C57/Bl6
C57
C57BL/6J (F129+51)
C57 black subline 6
B/6
Bl/6
C57BL/6J wild-type
WT
Black 6
C57 Black
wild type
C57BL/6J+/+
p53 wild-type (+/+)
C57BL6/J
C57BL/6J, H-2b
C57/B16
wild-type
C57BL
B6 WT
wild-type (WT)
WT-Control
WT-CR
C57/Bl 6J
C57/Bl
p21+/+p27+/+
control
Ctr
C57BL/6J (UW)
B6J
C57BL/6J inbred WT
C57 BL/6
Wild-type (WT) C57BL/6J
Strain Sex
Unspecified
Reproductive Status
reproductive status not specified
Age of Detection
35 days