Pathology Image Detail

Caption

Kidney - normal tissue. There is moderate labeling of the cytoplasm of all cells of all proximal tubules and of the nucleus of most of these cells (tissues fixed in Fekete's fixative, heat-mediated antigen retrieval in citrate buffer at pH=6.0, 1:100 dilution). This labeling is interpreted as an artifact. Cytoplasmic labeling of proximal renal tubules may be the result of endogenous biotin.

Description

Kidney - Normal tissue. Cyclin B1 immunohistochemistry, artifact

Age at Necropsy

unknown

Contributor

Mikaelian I (J:94320)

Pathologist

Mikaelian I (J:94320)

Method

IHC for cyclin B1
Image Probes

Type: antibody

Name
anti-cyclin B1 (100-401-152)
Target
human cyclin B1
Supplier
Rockland, Inc.
Notes
"This product was prepared from monospecific antiserum by delipidation and defibrination. Antiserum will specifically react with a 62 kDa Cyclin B 1protein from human, rat and mouse tissue. No reaction was observed against other related cyclins."

Model

MMHC ID
MTB:27726
Tumor Name
Kidney • normal tissue (control)
Treatment Type
None (spontaneous)
Tumor Synonyms
kidney, normal tissue
Organ Affected
Kidney
Frequency
not applicable
Reference
J:94320

Strain

Strain
C57BL/6J
Strain Types
inbred
Strain Synonyms
wild-type C57BL/6J
C57Bl/6J
p53+/+
C57BL/6 from Jackson Laboratory
C57BL/6
B6
C57/Bl6
C57
C57BL/6J (F129+51)
C57 black subline 6
B/6
Bl/6
C57BL/6J wild-type
WT
Black 6
C57 Black
wild type
C57BL/6J+/+
p53 wild-type (+/+)
C57BL6/J
C57BL/6J, H-2b
C57/B16
wild-type
C57BL
B6 WT
wild-type (WT)
WT-Control
WT-CR
C57/Bl 6J
C57/Bl
p21+/+p27+/+
control
Ctr
C57BL/6J (UW)
B6J
C57BL/6J inbred WT
C57 BL/6
Wild-type (WT) C57BL/6J
Strain Sex
Unspecified
Reproductive Status
reproductive status not specified
Age of Detection
unknown