Pathology Image Detail

Caption

Lymph node - normal tissue. There is weak to moderate nuclear immunolabeling for cyclin A of lymphocytes located at the center of a germinative follicle as well as of a few lymphocytes scattered throughout the B area of this lymphoid follicle (antibody diluted at 1:10, tissue fixed in Fekete's solution, heat-mediated antigen retrieval in 0.1 mM EDTA at pH=7.5). There is a mild background staining.

Description

Lymph node lymphocytes - Normal tissue. Cyclin A immunohistochemistry

Age at Necropsy

35 days

Contributor

Mikaelian I (J:94320)

Pathologist

Mikaelian I (J:94320)

Method

IHC for cyclin A
Image Probes

Type: antibody

Name
anti-cyclin A (H-432) (sc-751)
Target
human cyclin A
Supplier
Santa Cruz Biotechnology
Notes
"affinity purified rabbit polyclonal antibody raised against a recombinant protein corresponding to amino acids 1-432 representing full length cyclin A of human origin."
"reacts with cyclin A (also designated cyclin A2) and cyclin A1"

Model

MMHC ID
MTB:27660
Tumor Name
Leukocyte - Lymphocyte • normal tissue (control)
Treatment Type
None (spontaneous)
Tumor Synonyms
lymph node lymphocytes, normal tissue
Organ Affected
Lymph node
Frequency
not applicable
Reference
J:94320

Strain

Strain
C57BL/6J
Strain Types
inbred
Strain Synonyms
wild-type C57BL/6J
C57Bl/6J
p53+/+
C57BL/6 from Jackson Laboratory
C57BL/6
B6
C57/Bl6
C57
C57BL/6J (F129+51)
C57 black subline 6
B/6
Bl/6
C57BL/6J wild-type
WT
Black 6
C57 Black
wild type
C57BL/6J+/+
p53 wild-type (+/+)
C57BL6/J
C57BL/6J, H-2b
C57/B16
wild-type
C57BL
B6 WT
wild-type (WT)
WT-Control
WT-CR
C57/Bl 6J
C57/Bl
p21+/+p27+/+
control
Ctr
C57BL/6J (UW)
B6J
C57BL/6J inbred WT
C57 BL/6
Wild-type (WT) C57BL/6J
Strain Sex
Unspecified
Reproductive Status
reproductive status not specified
Age of Detection
35 days