Pathology Image Detail

Caption

Skeletal muscle - normal tissue. There is strong labeling for fast-twitch skeletal myosin of about 75% muscle fibers. This figure should be compared the picture of a sequential section labeled for slow-twitch skeletal myosin. Labeling for slow- and fast-twitch skeletal myosin was mutually exclusive.

Description

Skeletal muscle - Normal tissue. Myosin (skeletal, fast) immunohistochemistry

Age at Necropsy

unknown

Contributor

Mikaelian I (J:94320)

Pathologist

Mikaelian I (J:94320)

Method

IHC for myosin (skeletal, fast)
Image Probes

Type: antibody

Name
anti-myosin (skeletal, fast) (M4276)
Target
rabbit muscle myosin
Supplier
Sigma-Aldrich
Notes
"Localizes an epitope on the myosin heavy chain. Stains the fast (type II) and neonatal isomyosin molecules found in skeletal muscle, but does not stain cardiac muscle, smooth muscle or non-muscle myosin in cultured cells."

Model

MMHC ID
MTB:27673
Tumor Name
Muscle - Striated - Skeletal • normal tissue (control)
Treatment Type
None (spontaneous)
Tumor Synonyms
skeletal muscle, normal tissue
Organ Affected
Muscle - Striated - Skeletal
Frequency
not applicable
Reference
J:94320

Strain

Strain
C57BL/6J
Strain Types
inbred
Strain Synonyms
wild-type C57BL/6J
C57Bl/6J
p53+/+
C57BL/6 from Jackson Laboratory
C57BL/6
B6
C57/Bl6
C57
C57BL/6J (F129+51)
C57 black subline 6
B/6
Bl/6
C57BL/6J wild-type
WT
Black 6
C57 Black
wild type
C57BL/6J+/+
p53 wild-type (+/+)
C57BL6/J
C57BL/6J, H-2b
C57/B16
wild-type
C57BL
B6 WT
wild-type (WT)
WT-Control
WT-CR
C57/Bl 6J
C57/Bl
p21+/+p27+/+
control
Ctr
C57BL/6J (UW)
B6J
C57BL/6J inbred WT
C57 BL/6
Wild-type (WT) C57BL/6J
Strain Sex
Unspecified
Reproductive Status
reproductive status not specified
Age of Detection
unknown