Pathology Image Detail

Caption

Pancreas and duodenum - normal tissue. There is moderate diffuse labeling of acinar cells of the exocrine pancreas and mild labeling of enterocytes at the tip of intestinal vili for filaggrin (tissues fixed in Bouin's solution, 1:5,000 dilution).

Description

Pancreas - Normal tissue. Filaggrin immunohistochemistry

Age at Necropsy

unknown

Contributor

Mikaelian I (J:94320)

Pathologist

Mikaelian I (J:94320)

Method

IHC for filaggrin
Image Probes

Type: antibody

Name
anti-filaggrin (PRB-417P)
Target
filaggrin, residues 24-39
Supplier
Covance
Notes
Monospecific polyclonal rabbit antibody raised against a peptide corresponding to residues 24-39 in the partial sequence of filaggrin, DSQVHSGVQVEGRRGH. This antibody was subsequently purified using peptide affinity chromatography.

Model

MMHC ID
MTB:27733
Tumor Name
Pancreas • normal tissue (control)
Treatment Type
None (spontaneous)
Tumor Synonyms
pancreas, normal tissue
Organ Affected
Pancreas
Frequency
not applicable
Reference
J:94320

Strain

Strain
C57BL/6J
Strain Types
inbred
Strain Synonyms
wild-type C57BL/6J
C57Bl/6J
p53+/+
C57BL/6 from Jackson Laboratory
C57BL/6
B6
C57/Bl6
C57
C57BL/6J (F129+51)
C57 black subline 6
B/6
Bl/6
C57BL/6J wild-type
WT
Black 6
C57 Black
wild type
C57BL/6J+/+
p53 wild-type (+/+)
C57BL6/J
C57BL/6J, H-2b
C57/B16
wild-type
C57BL
B6 WT
wild-type (WT)
WT-Control
WT-CR
C57/Bl 6J
C57/Bl
p21+/+p27+/+
control
Ctr
C57BL/6J (UW)
B6J
C57BL/6J inbred WT
C57 BL/6
Wild-type (WT) C57BL/6J
Strain Sex
Unspecified
Reproductive Status
reproductive status not specified
Age of Detection
unknown