Pathology Image Detail

Caption

 Fig. 3C. Stomach: this is a cross section of a polypoid gastic mass. It is composed of variably ectatic gastric glands which lack atypia. The glands are separated by small bundles of smooth muscle fibers.

Description

 Hamartoma, polypoid, glandular stomach

Age at Necropsy

 280 days

Contributor

 Miyoshi H (J:76202)

Pathologist

 Mikaelian I (J:94320)

Copyright

 Reprinted by permission from the American Association for Cancer Research: Miyoshi H et al., "Gastrointestinal hamartomatous polyposis in Lkb1 heterozygous knockout mice." Cancer Res 2002 Apr 15;62(8):2261-6.

Method

 H&E

Model
MMHC ID
MTB:24824
Tumor Name
Stomach - Glandular • hamartoma
Treatment Type
None (spontaneous)
Tumor Synonyms
hamartoma, polypoid, glandular stomach
Organ Affected
Stomach - Glandular
Frequency
observed
Reference
J:76202

Strain
Strain
[not specified]-Stk11tm1Mmt/+
Strain Types
targeted mutation (knockout)
General Note
Heterozygous mice. The genetic background was not specified. It contains 129X1/SvJ (from the ES cell of origin of the targeted mutant allele).
Strain Synonyms
Lkb1 heterozygous knockout
Lkb1 (+/-)
Lkb1+/-
Lkb1+/-
Strain Sex
Female
Reproductive Status
reproductive status not specified
Age of Detection
280 days