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PDX Model Details
Stage / Grade:
AJCC IV /
and TM00302 originated from the same patient.
Race / Ethnicity:
White / Not Hispanic or Latino
(aka NSG or NOD Scid gamma)
Core needle biopsy
Tumor Mutation Burden
Sample from passage P1 has a TMB score of 8.08
TMB Range:0.81-305.22 (across all JAX PDX models)
TMB > 22 is considered high.
Variant Summary currently not available.
Hatched bars indicate genes with expression levels determined to be mildly affected by alignment calculations.
High degree of concordance between morphologic features of patient tumor compared to P0 tumor. P3 is a carcinoma but has lost adenocarcinoma differentiation.
Dr. Regina Gandour-Edwards, University of California, Davis
Patient tumor for PDX model TM00302. Sheets of pleomorphic carcinoma cells with vacuolated cytoplasm.
P0 tumor #130 for PDX model TM00302. Sheets of pleomorphic carcinoma cells with vacuolated cytoplasm.
P2 tumor F130 ID014 from model TM00302 stained for H&E. This is a 4x image.
P2 tumor F130 ID014 from model TM00302 stained for H&E. This is a 20x image.
P3 tumor F130 ID16 from model TM00302 stained for AE1AE3.